EGFR Positive Non-small Cell Lung Cancer (DBCOND0058575)

Identifiers

Synonyms
EGFR Mutation Positive Non Small Cell Lung Cancer / EGFR-mutant Non-small Cell Lung Cancer / Non-Small Cell Lung Cancer With EGFR Mutation / EGFR Mutation Positive Non-small Cell Lung Cancer / EGFR-Mutated Non-Small-Cell Lung Carcinoma / EGFR Mutated Non-small Cell Lung Cancer Patients / Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor / EGFR positive non-small cell lung cancer / Non-small cell lung cancer, positive for epidermal growth factor receptor expression (disorder) / Non-small cell lung cancer with mutation in epidermal growth factor receptor (disorder)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01838577
Genetics of EGFR (Epidermal Growth Factor Receptor) Mutation StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02906163
First Line Bio-immunotherapy With Thymosin Alpha 1 in Patients With Sensitizing EGFR Mutation Positive Non Small Cell Lung Cancer Who Are Taking Standard of Care Therapytreatment1 / 2unknown_status
NCT06208033
SMET12 and Toripalimab Combined Chemotherapy in Patients With EGFR Positive Advanced Non-small Cell Lung Cancer (NSCLC)treatment0not_yet_recruiting
NCT04105153
Real-world Analysis of Workup at Disease Progression and Implementation of Osimertinib for EGFR+ NSCLCNo drug interventionsNot AvailableNot Availablecompleted
NCT04643847
A Phase II Trial of Upfront Radiotherapy Plus Almonertinib for Epidermal Growth Factor Receptor(EGFR)-Mutant Non-small-cell Lung Cancer(NSCLC) Patients With Brain Metastasestreatment2unknown_status
NCT02729298
First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumorstreatment1completed
NCT05998993
Study to Evaluate SBRT for EGFR Mutant NSCLC Patients Receiving Osimertinib (CULTRO)No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02194556
Sequential and Maintenance Icotinib Plus Chemotherapy Versus Icotinib Maintenance After Chemotherapy in Advanced NSCLCtreatment4unknown_status
NCT05132985
Neoadjuvant Icotinib With Chemotherapy for Epidermal Growth Factor Receptor(EGFR)-Mutated Resectable Lung Adenocarcinomatreatment2not_yet_recruiting
NCT04640870
The Molecular Epidemiology of Epidermal Growth Factor Receptor (EGFR) Mutations in Patients With Advanced EGFR Mutation-positive Non-small Cell Lung Cancer Treated With AfatinibNot AvailableNot Availablecompleted
NCT03126799
A Study of Tarceva vs. Avastin+Tarceva for Advanced NSCLC With EGFR m(+)treatment2unknown_status
NCT05338619
A Study of Lazertinib as Consolidation Therapy in Patients With Locally Advanced, Unresectable, EGFR-Mutant Non-Small Cell Lung Cancer (Stage III) Following Chemoradiation Therapytreatment2recruiting
NCT06557096
CSF CTC-Capture-Guided EGFR-TKI and Bevacizumab Combination Therapy in EGFR-Mutant Advanced NSCLCtreatment0not_yet_recruiting
NCT02788058
A Study of Hypofractionated Radiotherapy for Limited Metastatic NSCLC Harboring Sensitizing EGFR Mutations After First Line TKI Therapytreatment2unknown_status
NCT04989322
Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLCtreatment2recruiting
NCT05573373
Pamiparib (BGB-290) Was Used in EGFR-TkIs Resistant Non-small Cell Lung Cancertreatment1recruiting
NCT04862780
(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLCtreatment1 / 2active_not_recruiting
NCT02125240
Icotinib Versus Placebo as Adjuvant Therapy in EGFR-mutant Lung Adenocarcinomatreatment3unknown_status
NCT04464967
Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancerstreatment1 / 2withdrawn
NCT05110950
Endobronchial Ultrasound Needle Aspiration With and Without SuctionNo drug interventionsdiagnosticNot Availableunknown_status
NCT03349203
Icotinib as Neoadjuvant and Adjuvant Therapy in EGFR-mutant Stage IIIB or Oligometastasis Non-small Cell Lung Cancertreatment2unknown_status
NCT05256290
Phase 1/2 Study of BDTX-1535 in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR MutationsNo drug interventionstreatment1 / 2recruiting
NCT05962021
Neoadjuvant Toripalimab for Non-squamous NSCLC With EGFR Mutationtreatment2not_yet_recruiting
NCT06352502
An Observational Study of Furmonertinib for EGFR Mutation-positive NSCLC Patients With Brain MetastasisNot AvailableNot Availablerecruiting
NCT04001777
A Study of APG-1252 Plus Osimertinib(AZD9291) in EGFR TKI Resistant NSCLC Patientstreatment1recruiting
NCT05263947
Bevacizumab Combined With Double Dose Icotinib in Patients With EGFR Exon 21-L858R Mutationtreatment2recruiting
NCT04027647
Phase 2 Study of Dacomitinib in NSCLCtreatment2active_not_recruiting
NCT06287593
The Feasibility of Dynamic Liquid Biopsy Monitoring During Neoadjuvant Treatment for EGFR-mutated NSCLCNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04504071
Dacomitinib in Lung Cancer With Uncommon EGFR Mutationstreatment2unknown_status
NCT03749213
Icotinib as Neoadjuvant Therapy in EGFR-mutant Stage ⅢA-N2 Non-small Cell Lung Cancertreatment2recruiting
NCT01665417
Icotinib as First-line and Maintenance Treatment in EGFR Mutated Patients With Lung Adenocarcinomatreatment4unknown_status
NCT05089916
Radiation During Osimertinib Treatment: a Safety and Efficacy Cohort Studytreatment2recruiting
NCT06109558
The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLCtreatment1 / 2recruiting
NCT04900935
Patient-centered, Optimal Integration of Survivorship and Palliative CareNo drug interventionssupportive_careNot Availablerecruiting
NCT02103257
Sequential Icotinib Plus Chemotherapy Versus Icotinib Alone as First-line Treatment in Stage IIIB/IV Lung Adenocarcinomatreatment4unknown_status
NCT05037331
Osimertinib for Advanced EGFR-positive NSCLC PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05033691
A Study to Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone, in Patients With EGFR Mutated NSCLC and Asymptomatic Brain MetastasesNo drug interventionstreatmentNot Availablerecruiting
NCT06207292
Stereotactic Ablative Radiotherapy in Synchronous and Metachronous Oligo-Metastatic Non Small Cell Lung CancerNo drug interventionstreatmentNot Availablerecruiting
NCT04965701
First Line Osimertinib in the Real World: an Inter-regional Prospective StudyNot AvailableNot Availablecompleted
NCT03382795
Retreatment With Epidermal Growth Factor Receptor(EGFR) Tyrosine Kinase Inhibitor in EGFR Mutation Positive PatientsNo drug interventionstreatment2unknown_status
NCT05165355
Adjuvant Targeted-therapy for Patients With Resected High-risk EGFR-mutant Stage IB-IIA Non-small Cell Lung CarcinomaNo drug interventionstreatment2recruiting
NCT05153408
(HARMONY) Study of BLU-701 in EGFR-mutant NSCLCtreatment1terminated
NCT03904823
A Study of Famitinib in Combination With HS-10296 in Patients With EGFR-mutant NSCLCtreatment2unknown_status
NCT03333343
Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLCtreatment1active_not_recruiting
NCT04824079
Keynatinib in Treated Patients With NSCLC and Brain MetastasesNo drug interventionstreatment2recruiting
NCT04770688
Advanced Lung Tumor Treated by Osimertinib Plus Anlotinibtreatment1 / 2completed
NCT06306456
A Phase Ib/II Clinical Study of GH21 Capsules Combined With Osimertinib Mesylate Tablets in Patients With NSCLCtreatment1 / 2recruiting
NCT05852990
Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLCtreatment3recruiting
NCT01776684
Evaluation of EGFR TKI Resistance Mechanism Using Plasma DNA AnalysisdiagnosticNot Availableunknown_status
NCT04538378
Olaparib (LYNPARZA) Plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas That Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine Tumorstreatment2recruiting
NCT01795352
Retrospective Study in a NSCLC M+ pNo drug interventionsNot AvailableNot Availablecompleted
NCT04141644
Safety and Efficacy of Combination Osimertinib and Ipilimumab in Patients w EGFR Mutated NSCLCtreatment1active_not_recruiting
NCT04216121
LAT for Oligoprogressive NSCLC Treated With First-line OSImertinibNo drug interventionsNot AvailableNot Availablerecruiting
NCT06102928
A Clinical Study of the Combination of Anlotinib and Aumolertinib in the First-line Treatment of Advanced NSCLC With EGFR 21L858R MutationtreatmentNot Availablerecruiting
NCT04619004
HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung CancerNo drug interventionstreatment2active_not_recruiting