delayed chemotherapy-induced nausea and vomiting (DBCOND0024029)
Identifiers
- Synonyms
- Delayed Nausea and Vomiting caused by Chemotherapy / Delayed chemotherapy induced nausea and vomiting / Delayed chemotherapy induced naused and vomiting / Delayed Chemotherapy-Induced Nausea and Vomiting
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Netupitant An antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy.- Substance-P receptortarget
- Cytochrome P450 3A43enzyme
- Cytochrome P450 2C9enzyme
- Cytochrome P450 2D6enzyme
- Cytochrome P450 3A4enzyme
- ATP-dependent translocase ABCB1transporter
Palonosetron A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.- 5-hydroxytryptamine receptor 3Atarget
- Cytochrome P450 2D6enzyme
- Cytochrome P450 3A4enzyme
- Cytochrome P450 1A2enzyme
Rolapitant A neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy.- Substance-P receptortarget
- Cytochrome P450 2D6enzyme
- Cytochrome P450 3A4enzyme
- Broad substrate specificity ATP-binding cassette transporter ABCG2transporter
- ATP-dependent translocase ABCB1transporter
- Clinical Trials
- Not Available