Sepsis, Neonatal (DBCOND0160617)

Identifiers

Synonyms
Neonatal Sepsis / Sepsis neonatal / Neonatal septicemia / Neonatal septicaemia / Sepsis of the newborn (disorder) / Sepsis neonatorum / Bacterial sepsis of newborn, unspecified / Bacterial sepsis of newborn (disorder) / Bacterial sepsis of newborn

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Amikacin
An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06145841
Metagenomic Next-Generation Sequencing Guides Anti-Infection StrategiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT06018792
Molecular Culture for the Diagnosis of Pediatric SepsisNo drug interventionsNot AvailableNot Availablerecruiting
NCT06414174
Comparison Between Split Septum and Mechanical Valve Needleless Connector in Preterm BabiesNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT06633770
Role of Presepsin as a Novel Biomarker in Diagnosis of Neonatal SepsisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05856227
Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Agetreatment3recruiting
NCT06592586
A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant WomenNo drug interventionsprevention2 / 3not_yet_recruiting
NCT01290003
Role of Antibiotics in Preventing Infection in Babies Born Through Meconium Stained LiquorpreventionNot Availablecompleted
NCT03721302
NeoAMR Observational Study in Neonatal SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT00942084
A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo)treatment1completed
NCT05730387
Smart Discharges for Mom & BabyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05156333
Probiotics and GBS Colonization in PregnancyNo drug interventionspreventionNot Availablesuspended
NCT05569551
Umbilical Cord Care in Term Neonates: The Role of Wondaleaf Adhesive Pouch (WLAP)No drug interventionssupportive_careNot Availablecompleted
NCT04528251
Comparison of the Effectiveness of Two Different Antibiotic Regimens of the Treatment of Pregnant Women With Preterm Rupture of MembranesNo drug interventionsNot AvailableNot Availableunknown_status
NCT04800445
Salivary C- Reactive Protein, Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for Neonatal SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05490498
Study of the Breast Milk Microbiota and Its Influence on the Development of Early and Late Neonatal Bacterial Sepsis Under Three Months of Age.No drug interventionsotherNot Availablerecruiting
NCT06411405
Using Machine Learning to Model Early-onset Neonatal Sepsis Risk in Uganda and ZimbabweNo drug interventionsNot AvailableNot Availablerecruiting
NCT03590483
Outcomes in Spontaneous and ART Twin PregnanciesNo drug interventionsNot AvailableNot Availablecompleted
NCT05692128
Frequency and Severity of Thrombocytopenia in Neonatal SepsisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01539356
Hepcidin Levels in Preterm InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT04039152
Clinical Impact of an Antibiotic Stewardship Program in a Neonatal Intensive Care UnitNo drug interventionsNot AvailableNot Availablecompleted
NCT05226949
Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT04110418
Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm Neonatetreatment2unknown_status
NCT00947518
Safety of Skin Cleansing With Chlorhexidine in Preterm Low Birth Weight InfantspreventionNot Availablecompleted
NCT03291496
Microfluidic Assessment of Clinical Outcomes in Preterm NewbornsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02473796
Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCTNo drug interventionshealth_services_researchNot Availablecompleted
NCT04455022
The Volume of Blood Submitted for Culture in Neonates - a Multicentre Quality Improvement Initiative.No drug interventionsNot AvailableNot Availableunknown_status
NCT03403530
Efficacy of IgM Rich Immunoglobulin With Antibiotics for Bacterial Sepsis in Very Low Birth Weight Preterm Neonatestreatment4completed
NCT03308526
Prevailing Microorganisms Causing Neonatal Sepsis in Neonatal Intensive Care Unit (Prospective Study)Prevailing Microorganisms Causing Neonatal Sepsis in Neonatal Intensive Care Unit (Prospective Study)No drug interventionsNot AvailableNot Availableunknown_status
NCT04742582
Potential Protective Effect of a Formula Supplemented With Fermented Matrices on the Risk of Developing Neonatal SepsisNo drug interventionspreventionNot Availableunknown_status
NCT04474327
Role of Montelukast in Modulation of Response to Sepsis in Preterm Infantstreatment1completed
NCT05089760
Microbiology, Antimicrobial Resistance and Outcomes of Neonatal Sepsis in ChinaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03871491
Azithromycin-Prevention in Labor Use Study (A-PLUS)prevention3active_not_recruiting
NCT03403062
Prognostic Value of Red Cell Distribution Width (RDW) in Neonatal SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01027429
Simplified Antibiotic Therapy for Sepsis in Young Infantstreatment3completed
NCT01821989
Oral Lactoferrin Supplementation for Prevention of Sepsis in Preterm NeonateNo drug interventionsprevention0unknown_status
NCT01005589
CD64 Measurement in Neonatal Infection and Necrotising EnterocolitisNo drug interventionsNot AvailableNot Availablecompleted
NCT03310840
A Study on Ventilator-associated Pneumonia as a Risk for Nosocomial Infection in Mechanically Ventilated Neonates In NICU of Assiut University Children Hospital (Nicu Eta)No drug interventionsNot AvailableNot Availablecompleted
NCT00866567
Defects in Opsonophagocytosis in Premature InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT03513146
Oropharyngeal Administration of Mother's Milk in Preterm Infants and Neonatal InfectionNo drug interventionspreventionNot Availablecompleted
NCT02468310
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in GhanaNo drug interventionshealth_services_researchNot Availablecompleted
NCT01479114
Effect of Recombinant Human Granulocyte Colony- Stimulating Factor on CD11b in Septic Neonatestreatment4completed
NCT00861055
Neonatal Sepsis and GBS Carriage StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02061150
Neonatal Sepsis Workup for High Risk Newborns - Evaluation of Need and Ways to PreventNo drug interventionsNot AvailableNot Availableunknown_status
NCT03354650
Epidemiology of Neonatal Sepsis in Neonatal Intensive Care Unit in Assiut University Children HospitalNo drug interventionsNot AvailableNot Availableunknown_status
NCT05022043
Serum Presepsin as Early Predictor for Neonatal Early-onset SepsisNo drug interventionsdiagnosticNot Availablecompleted
NCT05343403
Parental Participation on the Neonatal Ward - the neoPARTNER StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02281890
Neurodevelopmental Outcomes After Suspected or Proven Sepsis: Secondary Analysis of INIS Trial DatabaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03008421
Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late PregnancyNo drug interventionstreatmentNot Availablecompleted
NCT02797353
Strengthening Maternal Neonatal and Child Health Services in a Rural District of PakistanNo drug interventionshealth_services_researchNot Availablecompleted
NCT06113653
Outcomes and Predictors of Mortality Among Preterm Infants With Neonatal SepsisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05742477
Treatment Outcome With Antibiotic Use and Its Resistance Pattern Among Patient With Neonatal SepsisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03453177
Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsistreatment2completed
NCT03280147
7 Days Versus 14 Days of Antibiotics for Neonatal SepsisNo drug interventionstreatment3completed
NCT03199547
Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Deathprevention3completed
NCT03278847
Optimising Newborn Nutrition During Therapeutic Hypothermia.No drug interventionsNot AvailableNot Availablecompleted
NCT03880305
White Blood Cells and Platelets Indices as a Prognostic Factor in Neonatal SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT04094597
Safety and Efficacy of Oral Bovine Lactoferrinprevention0completed
NCT02486783
Infection, Sepsis and Meningitis in Surinamese NeonatesNo drug interventionsNot AvailableNot Availablecompleted
NCT01177111
Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in NepalNo drug interventionsprevention3completed
NCT03896893
Neonatal Bacterial Colonization StudyNo drug interventionspreventionNot Availableunknown_status
NCT01120678
Improved Detection of Neonatal Sepsis Using a Targeted Biomarker AssayNo drug interventionsNot AvailableNot Availablecompleted
NCT03578978
A Panel of Biomarkers in Diagnosing Late-onset Neonatal Sepsis and Necrotizing Enterocolitis in Sibu HospitalNo drug interventionsNot AvailableNot Availableunknown_status
NCT03795285
The Role of Neutrophil CD64 and Soluble Triggering Receptor Expressed on Myeloid Cells 1 in Neonatal SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05127070
Evaluating the NeoTree in Malawi and ZimbabweNo drug interventionsNot AvailableNot Availableunknown_status
NCT00800449
Distribution of Haptoglobin Phenotype in Septic and Non Septic Pre-term Neonates (PTSH)No drug interventionsNot AvailableNot Availablecompleted
NCT05416918
Clinical Value of Metagenomic Sequencing in Neonatal SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT03431558
Bovine Lactoferrin and Neonatal Survival in Low Birth Weight Babies.No drug interventionsprevention3unknown_status
NCT03755635
Neonatal Sepsis at Neonatal Intensive Care Units in GhanaNo drug interventionspreventionNot Availablecompleted
NCT05585957
THE VALUE OF INTERLEUKIN 6 AS A DIAGNOSTIC MARKER IN NEONATAL SEPSISNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT05114057
Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKINo drug interventionsscreeningNot Availablenot_yet_recruiting
NCT02954926
Intravenous Immunoglobulin in Prevention of Preterm Neonatal SepsisNo drug interventionsprevention3completed
NCT01350765
Naushero Feroze Neonatal Survival ProjectNo drug interventionshealth_services_researchNot Availablecompleted
NCT01294865
Soluble Urokinase Plasminogen Activator Receptor (suPAR) in Late-onset Neonatal SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05985174
Role of Neutrophil CD64 and Monocyte HLA-DR Markers in the Dignosis of Neonatal SepsisNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT03247920
Reduction of Intravenous Antibiotics In Neonatestreatment4completed
NCT01214473
Probiotics for Prevention Neonatal InfectionNo drug interventionspreventionNot Availableterminated
NCT02147327
Effects of Cord Blood 25-hydroxy-vitamin D Level on Early Neonatal MorbiditiesNo drug interventionsNot AvailableNot Availablecompleted
NCT03295162
Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsissupportive_care1 / 2completed
NCT02959229
Early Versus Late Lactoferrin in Prevention of Neonatal Sepsisprevention4completed
NCT03498989
Effect of Early Feeding of Breast MilkNo drug interventionspreventionNot Availableunknown_status
NCT02386592
Prevention of Nosocomial Bacteremia Among Zambian NeonatespreventionNot Availablecompleted
NCT01723501
Chlorhexidine Skin Application for Prevention of Infection in Infants Weighing <1500 g at Birthprevention2 / 3withdrawn
NCT06306001
Intravenous Methylene Blue for Treating Refractory Neonatal Septic Shocktreatment2 / 3not_yet_recruiting
NCT04172012
Use of Probiotics to Reduce Infections, Death and ESBL Colonisationprevention3active_not_recruiting
NCT01676610
Infant Pulse Oximetry in Pakistan StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06002295
A Comparative Analysis of 4% Chlorhexidine Versus Methylated Spirit as Prophylaxis of Omphalitis and Sepsis in Newbornstreatment2completed
NCT03746743
Severity Index of Neonatal Septicemia Using Score for Neonatal Acute Physiology (SNAP) IINo drug interventionsNot AvailableNot Availablecompleted