Halothane is a general inhalation anesthetic used for the induction and maintenance of general anesthesia. A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement.
- Mechanism
- Curator reviewed
Halothane causes general anaethesia due to its actions on multiple ion channels, which ultimately depresses nerve conduction, breathing, cardiac contractility. Its immobilizing effects have been attributed to its binding to potassium channels in cholinergic neurons. Halothane's effect are also likely due to binding to NMDA and calcium channels, causing hyperpolarization.
- Primary indication
- For the induction and maintenance of general anesthesiaCurator reviewed · 2 structured indications
- Formula / weight
- C2HBrClF3 · 197.382 g/mol (avg)
- First approval
- Canada, 2005 · United States, 1975
- Also known as
- Bromochlorotrifluoroethane
Resolves to
BCQZXOMGPXTTIC-UHFFFAOYSA-NSMILES[H]C(Cl)(Br)C(F)(F)FWhat you can answer from here — as of September 21, 2026
Which drugs share a target with Halothane, and which of those have an active Phase 3 trial?
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