- Anesthetics, General
- Accession Number
Agents that induce various degrees of analgesia; depression of consciousness, circulation, and respiration; relaxation of skeletal muscle; reduction of reflex activity; and amnesia. There are two types of general anesthetics, inhalation and intravenous. With either type, the arterial concentration of drug required to induce anesthesia varies with the condition of the patient, the desired depth of anesthesia, and the concomitant use of other drugs. (From AMA Drug Evaluations Annual, 1994, p.173)
- ATC Classification
Drug Drug Description Enflurane A halogenated inhalational anesthetic agent used for the induction and maintenance of anesthesia and for analgesia during labor and delivery. Etomidate A short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. Sufentanil An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain. Isoflurane An inhaled general anesthetic used in surgery. Alfentanil An opioid agonist used to induce and maintain anesthesia, as well as an analgesic. Propofol A medication used in general anesthesia and for sedation. Remifentanil An opioid analgesic used in anesthesia. Halothane A general inhalation anesthetic used for the induction and maintenance of general anesthesia. Desflurane A general inhalation anesthetic for inpatient and outpatient surgery in adults. Ketamine A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. Sevoflurane A inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures. Nitrous oxide An inhalatory gas used as an adjunct to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in certain neonates with hypoxic respiratory failure. Propanidid An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918) Trichloroethylene Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. It has been sold under a variety of... Xenon Not Annotated Diethyl ether Not Annotated Sodium oxybate A central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy. Methohexital An anesthetic used to induce deep sedation. Thiopental A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. Fentanyl An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. Diazepam A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. Methoxyflurane For use in the induction and maintenance of general anesthesia Thiamylal Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state. gamma-Hydroxybutyric acid Used as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance. Urethane Urethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963. Tiletamine This drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt... Anileridine An opioid analgesic used to treat moderate to severe pain. Alfaxalone Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use... Chloroform Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on... Enibomal Not Annotated Phenoperidine Not Annotated Vinyl ether Not Annotated Tetracaine A local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. Hexobarbital For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful... Fospropofol A sedative-hypnotic agent indicated for monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures. Dexmedetomidine An alpha-2 agonist used for sedation during various procedures. Clonidine An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. Esketamine A NMDA receptor antagonist used for treatment-resistant depression.
- Drugs & Drug Targets