Anesthetics, General

Name
Anesthetics, General
Accession Number
DBCAT000563
Description

Agents that induce various degrees of analgesia; depression of consciousness, circulation, and respiration; relaxation of skeletal muscle; reduction of reflex activity; and amnesia. There are two types of general anesthetics, inhalation and intravenous. With either type, the arterial concentration of drug required to induce anesthesia varies with the condition of the patient, the desired depth of anesthesia, and the concomitant use of other drugs. (From AMA Drug Evaluations Annual, 1994, p.173)

Drugs
DrugDrug Description
AlfaxaloneAlfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use...
AlfentanilAn opioid agonist used to induce and maintain anesthesia, as well as an analgesic.
AnileridineAn opioid analgesic used to treat moderate to severe pain.
ChloraloseChloralose is a small molecule drug. Chloralose has a monoisotopic molecular weight of 307.96 Da.
ChloroformChloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on...
CipepofolAn alkylphenol GABA-A positive allosteric modulator used for induction of general anesthesia in adults undergoing surgery.
ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
DesfluraneA general inhalation anesthetic for inpatient and outpatient surgery in adults.
DexmedetomidineAn alpha-2 agonist used for sedation during various procedures.
DiazepamA long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
Diethyl etherNot Annotated
EnfluraneA halogenated inhalational anesthetic agent used for the induction and maintenance of anesthesia and for analgesia during labor and delivery.
EnibomalNot Annotated
EsketamineA NMDA receptor antagonist used for treatment-resistant depression.
EtomidateA short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures.
FentanylAn opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management.
FospropofolA sedative-­hypnotic agent indicated for monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures.
gamma-Hydroxybutyric acidGamma-hydroxybutyric acid is a central nervous system depressant indicated for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients aged 7 years and older with narcolepsy, as well...
HalothaneA general inhalation anesthetic used for the induction and maintenance of general anesthesia.
HexobarbitalFor the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful...
IsofluraneAn inhaled general anesthetic used in surgery.
KetamineA rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
MethohexitalAn anesthetic used to induce deep sedation.
MethoxyfluraneFor use in the induction and maintenance of general anesthesia
Nitrous oxideAn inhalatory gas used as an adjunct to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in certain neonates with hypoxic respiratory failure.
PhenoperidineNot Annotated
PropanididAn intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)
PropofolA medication used in general anesthesia and for sedation.
Propofol HemisuccinateNot Annotated
RemifentanilAn opioid analgesic used in anesthesia.
SevofluraneA inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures.
Sodium oxybateA central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy.
SufentanilAn opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain.
TetracaineA local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures.
ThiamylalUsed for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
ThiopentalA barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
TiletamineThis drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt...
TrichloroethyleneTrichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. It has been sold under a variety of...
UrethaneUrethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963.
Vinyl etherNot Annotated
XenonNot Annotated