Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins

Name
Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins
Accession Number
DBCAT002098
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
SermorelinFor the treatment of dwarfism, prevention of HIV-induced weight loss
Salmon calcitoninA synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
DesmopressinA synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia.
GlucagonA form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures.
CetrorelixA synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy.
SomatotropinA recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.
PegvisomantA growth hormone receptor antagonist used to treat acromegaly.
OctreotideA peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.
LiothyronineA thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism.
CarbimazoleA drug used for the reduction of thyroid function.
LevothyroxineA synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.
PropylthiouracilA thiourea antithyroid agent used to treat hyperthyroidism.
GonadorelinA synthetic GnRH used to test the function of gonadotropes and the pituitary.
NafarelinA gonadotropin releasing hormone agonist used to treat central precocious puberty.
FludrocortisoneA mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.
MethimazoleA thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
ParicalcitolA vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
TrilostaneUsed in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
MecaserminA recombinant insulin-like growth factor-1 used for the long-term treatment of growth failure in pediatric patients with primary IGF-1 deficiency or with growth hormone gene deletion due to the development of neutralizing antibodies to GH.
CarbetocinAn oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth.
TetracosactideA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
ParamethasoneFor the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
TerlipressinA drug used to treat bleeding caused by esophageal varices.
AldosteroneA hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
VapreotideFor the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
Parathyroid hormoneAn analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism.
TeriparatideA recombinant parathyroid hormone used for the treatment of osteoporosis.
DoxercalciferolA synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis.
PasireotideA somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate.
Human calcitoninHuman calcitonin is indicated for the treatment of Paget's disease in the cases where the use of salmon calcitonin may provoke the generation of high-titer of antibodies. Paget's disease is...
GanirelixA GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges.
LanreotideA somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly.
DibromotyrosineNot Available
TesamorelinA growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy.
SomatremA recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age.
SomatostatinA natural peptide hormone used to treat acute bleeding from esophageal varices, gastrointestinal ulcers, and gastritis; prevent pancreatic complications after surgery; and restrict secretions of the upper intestine, pancreas, and biliary tract.
MeprednisoneNot Annotated
Potassium perchlorateNo current FDA- or EMA-approved therapeutic indications.
DeflazacortA corticosteroid used to treat Duchenne muscular dystrophy.
CortivazolCortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).
Calcitonin porcineCalcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. Human calcitonin...
PrednylidenePrednylidene is an experimental systemic glucocorticoid.
OrnipressinNot Annotated
MethylthiouracilNot Annotated
ElcatoninNot Annotated
DemoxytocinNot Annotated
BenzylthiouracilNot Annotated
CloprednolA glucocorticoid indicated in the treatment of arthritis and asthma.
Thyrotropin alfaA recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue.
OxytocinA recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
RimexoloneA glucocorticoid used to treat inflammation of the eye.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
FluocortoloneA glucocorticoid used topically for localized skin reactions and also orally for systemic use.
LypressinNot Annotated
TiratricolA metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.
EtelcalcetideA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in patients with chronic kidney disease who require hemodialysis.
CortisoneA naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to...
Mecasermin rinfabateMecasermin rinfabate was approved for treatment of severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) ....
OsilodrostatAn oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
ElagolixA gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis.
DesoxycortoneNot Annotated
CalcifediolAn active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients.
NorethisteroneA synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis.
EstradiolAn estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
AbaloparatideA parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in patients with a high risk of fracture.
RelugolixAn oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.
SomatrogonA long-acting recombinant human growth hormone used as the long-term treatment of pediatric patients who have growth failure due to growth hormone deficiency.
SomapacitanA human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency.
LinzagolixA selective gonadotropin-releasing hormone (GnRH) receptor antagonist used for the symptomatic treatment of uterine fibroids.
LevoketoconazoleOne of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing's syndrome.
DasiglucagonA glucagon analog used to treat severe hypoglycemia in pediatric and adult patients with diabetes.
LonapegsomatropinA human growth hormone indicated in the treatment of growth failure due to inadequate endogenous growth hormone secretion.
EvocalcetEvocalcet has been used in trials studying the treatment of Hyperparathyroidism and Secondary Hyperparathyroidism.
VamoroloneA synthetic glucocorticoid used as an anti-inflammatory and immunosuppressant in the management of Duchenne muscular dystrophy (DMD).
PalopegteriparatideA parathyroid hormone analog used to treat hyperparathyroidism in adults.
Drugs & Drug Targets
DrugTargetType
SermorelinGrowth hormone-releasing hormone receptortarget
Salmon calcitoninCalcitonin receptortarget
DesmopressinVasopressin V1a receptortarget
DesmopressinVasopressin V1b receptortarget
DesmopressinVasopressin V2 receptortarget
DesmopressinProstaglandin G/H synthase 1enzyme
DesmopressinProstaglandin G/H synthase 2enzyme
DesmopressinOxytocin receptortarget
GlucagonGlucagon receptortarget
GlucagonGlucagon-like peptide 2 receptortarget
GlucagonGlucagon-like peptide 1 receptortarget
CetrorelixLutropin-choriogonadotropic hormone receptortarget
CetrorelixGonadotropin-releasing hormone receptortarget
SomatotropinGrowth hormone receptortarget
SomatotropinProlactin receptortarget
SomatotropinCytochrome P450 1A2enzyme
SomatotropinCytochrome P450 2C19enzyme
SomatotropinATP-dependent translocase ABCB1transporter
PegvisomantGrowth hormone receptortarget
PegvisomantSterol 26-hydroxylase, mitochondrialenzyme
PegvisomantGlutamine synthetaseenzyme
PegvisomantCytochrome P450 3A4enzyme
PegvisomantCholinesteraseenzyme
PegvisomantCytochrome P450 4A11enzyme
OctreotideMyeloperoxidaseenzyme
OctreotideCytochrome P450 3A4enzyme
OctreotideSomatostatin receptortarget
OctreotideAlbumincarrier
OctreotideATP-dependent translocase ABCB1transporter
OctreotideATP-binding cassette sub-family C member 2transporter
OctreotideSomatostatin receptor type 2target
LiothyronineThyroid hormone receptor betatarget
LiothyronineThyroid hormone receptor alphatarget
LiothyronineThyroxine-binding globulincarrier
LiothyronineTransthyretincarrier
LiothyronineAlbumincarrier
LiothyronineATP-dependent translocase ABCB1transporter
LiothyronineOrganic anion transporter 3transporter
LiothyronineMonocarboxylate transporter 10transporter
LiothyronineSolute carrier organic anion transporter family member 4A1transporter
LiothyronineSolute carrier organic anion transporter family member 1C1transporter
LiothyronineSolute carrier organic anion transporter family member 1A2transporter
LiothyronineHepatic sodium/bile acid cotransportertransporter
LiothyronineSolute carrier organic anion transporter family member 4C1transporter
LiothyronineSolute carrier organic anion transporter family member 1B3transporter
LiothyronineSolute carrier organic anion transporter family member 1B1transporter
LiothyronineLarge neutral amino acids transporter small subunit 1transporter
LiothyronineProliferating cell nuclear antigentarget
LiothyronineUDP-glucuronosyltransferase 1A1enzyme
CarbimazoleThyroid peroxidasetarget
CarbimazoleAromataseenzyme
LevothyroxineThyroid hormone receptor alphatarget
LevothyroxineThyroid hormone receptor betatarget
LevothyroxineCytochrome P450 2C8enzyme
LevothyroxineTransthyretincarrier
LevothyroxineAlbumincarrier
LevothyroxineThyroxine-binding globulincarrier
LevothyroxineATP-dependent translocase ABCB1transporter
LevothyroxineMonocarboxylate transporter 8transporter
LevothyroxineSolute carrier organic anion transporter family member 1C1transporter
LevothyroxineSolute carrier organic anion transporter family member 1A2transporter
LevothyroxineSolute carrier organic anion transporter family member 1B1transporter
LevothyroxineSolute carrier organic anion transporter family member 4A1transporter
LevothyroxineLarge neutral amino acids transporter small subunit 1transporter
LevothyroxineUDP-glucuronosyltransferase 1A1enzyme
LevothyroxineSolute carrier organic anion transporter family member 2B1transporter
LevothyroxineIntegrin alpha-Vtarget
LevothyroxineIntegrin beta-3target
LevothyroxineATP-dependent translocase ABCB1enzyme
PropylthiouracilThyroid peroxidasetarget
PropylthiouracilMyeloperoxidaseenzyme
PropylthiouracilDopamine beta-hydroxylaseenzyme
PropylthiouracilCytochrome P450 1A1enzyme
PropylthiouracilType I iodothyronine deiodinasetarget
GonadorelinGonadotropin-releasing hormone receptortarget
GonadorelinPutative gonadotropin-releasing hormone II receptortarget
NafarelinGonadotropin-releasing hormone receptortarget
NafarelinPutative gonadotropin-releasing hormone II receptortarget
FludrocortisoneMineralocorticoid receptortarget
FludrocortisoneGlucocorticoid receptortarget
FludrocortisoneCytochrome P450 3A4enzyme
Fludrocortisone11-beta-hydroxysteroid dehydrogenase type 2enzyme
Fludrocortisone11-beta-hydroxysteroid dehydrogenase 1enzyme
FludrocortisoneAlbumincarrier
FludrocortisoneCorticosteroid-binding globulincarrier
FludrocortisoneAndrogen receptortarget
MethimazoleThyroid peroxidasetarget
MethimazoleCytochrome P450 1A2enzyme
MethimazoleCytochrome P450 2A6enzyme
MethimazoleCytochrome P450 2B6enzyme
MethimazoleCytochrome P450 2C19enzyme
MethimazoleCytochrome P450 2C9enzyme
MethimazoleCytochrome P450 2D6enzyme
MethimazoleCytochrome P450 2E1enzyme
MethimazoleCytochrome P450 3A4enzyme
MethimazoleFlavin-containing monooxygenase 3enzyme
ParicalcitolVitamin D3 receptortarget
Paricalcitol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
ParicalcitolCytochrome P450 3A4enzyme
ParicalcitolUDP-glucuronosyltransferase 1A4enzyme
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneATP-dependent translocase ABCB1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneAlbumincarrier
CinacalcetExtracellular calcium-sensing receptortarget
CinacalcetCytochrome P450 3A4enzyme
CinacalcetCytochrome P450 2D6enzyme
CinacalcetCytochrome P450 1A2enzyme
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2target
TrilostaneEstrogen receptor betatarget
TrilostaneEstrogen receptortarget
MecaserminInsulin-like growth factor 1 receptortarget
MecaserminInsulin-like growth factor-binding protein 3target
MecaserminInsulin receptortarget
MecaserminCation-independent mannose-6-phosphate receptortarget
MecaserminInsulin-like growth factor-binding protein 3carrier
MecaserminInsulin-like growth factor-binding protein complex acid labile subunitcarrier
MecaserminInsulin-like growth factor-binding protein 1carrier
MecaserminInsulin-like growth factor-binding protein 2carrier
MecaserminInsulin-like growth factor-binding protein 4carrier
MecaserminInsulin-like growth factor-binding protein 5carrier
MecaserminInsulin-like growth factor-binding protein 6carrier
CarbetocinOxytocin receptortarget
TetracosactideAdrenocorticotropic hormone receptortarget
CorticotropinAdrenocorticotropic hormone receptortarget
CorticotropinCorticoliberintarget
Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CorticotropinCytochrome P450 3A4enzyme
ParamethasoneCorticosteroid-binding globulincarrier
ParamethasoneGlucocorticoid receptortarget
ParamethasoneCytochrome P450 3A4enzyme
ParamethasoneCytochrome P450 3A5enzyme
ParamethasoneCorticosteroid-binding globulintarget
TerlipressinVasopressin V1a receptortarget
TerlipressinVasopressin V2 receptortarget
TerlipressinVasopressin V1b receptortarget
AldosteroneMineralocorticoid receptortarget
AldosteroneATP-dependent translocase ABCB1transporter
AldosteroneOrganic cation/carnitine transporter 2transporter
AldosteroneSolute carrier organic anion transporter family member 1A2transporter
AldosteroneCytochrome P450 11B1, mitochondrialenzyme
AldosteroneCytochrome P450 11B2, mitochondrialenzyme
AldosteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
AldosteroneGlucocorticoid receptortarget
AldosteroneCytochrome P450 3A4enzyme
AldosteroneSolute carrier family 12 member 1target
VapreotideSubstance-P receptortarget
VapreotideSomatostatin receptor type 2target
VapreotideSomatostatin receptor type 5target
VapreotideCytochrome P450 3A4enzyme
Parathyroid hormoneParathyroid hormone/parathyroid hormone-related peptide receptortarget
Parathyroid hormoneParathyroid hormone 2 receptortarget
TeriparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
TeriparatideParathyroid hormonetarget
DoxercalciferolSterol 26-hydroxylase, mitochondrialenzyme
DoxercalciferolVitamin D3 receptortarget
PasireotideSomatostatin receptor type 1target
PasireotideSomatostatin receptor type 2target
PasireotideSomatostatin receptor type 3target
PasireotideSomatostatin receptor type 5target
PasireotideCytochrome P450 3A4enzyme
Human calcitoninAlpha-actinin-1target
Human calcitoninAlpha-N-acetylglucosaminidaseenzyme
Human calcitoninAminopeptidase Nenzyme
Human calcitoninPhosphoglucomutase-1enzyme
GanirelixGonadotropin-releasing hormone receptortarget
LanreotideSomatostatin receptor type 2target
LanreotideSomatostatin receptor type 5target
LanreotideCytochrome P450 3A4enzyme
DibromotyrosineErythropoietin receptortarget
TesamorelinGrowth hormone-releasing hormone receptortarget
SomatremGrowth hormone receptortarget
SomatremInsulin-like growth factor 1 receptortarget
SomatostatinSomatostatin receptor type 1target
SomatostatinSomatostatin receptor type 2target
SomatostatinSomatostatin receptor type 3target
SomatostatinSomatostatin receptor type 4target
SomatostatinSomatostatin receptor type 5target
SomatostatinATP-dependent translocase ABCB1transporter
SomatostatinCytochrome P450 3A4enzyme
SomatostatinMu-type opioid receptortarget
SomatostatinDelta-type opioid receptortarget
MeprednisoneAlbumincarrier
MeprednisoneCytochrome P450 3A4enzyme
MeprednisoneCytochrome P450 3A5enzyme
MeprednisoneGlucocorticoid receptortarget
Potassium perchlorateSodium/iodide cotransportertarget
Potassium perchlorateAlbumincarrier
DeflazacortCytochrome P450 3A4enzyme
DeflazacortGlucocorticoid receptortarget
DeflazacortCytochrome P450 3A5enzyme
CortivazolGlucocorticoid receptortarget
CortivazolCytochrome P450 3A4enzyme
CortivazolCytochrome P450 3A5enzyme
PrednylideneCytochrome P450 3A4enzyme
PrednylideneCytochrome P450 3A5enzyme
CloprednolCytochrome P450 3A4enzyme
CloprednolCytochrome P450 3A5enzyme
Thyrotropin alfaThyrotropin receptortarget
OxytocinOxytocin receptortarget
OxytocinProlyl endopeptidaseenzyme
OxytocinOxytocin-neurophysin 1carrier
OxytocinLeucyl-cystinyl aminopeptidaseenzyme
OxytocinAdvanced glycosylation end product-specific receptortransporter
OxytocinVasopressin V1a receptortarget
OxytocinVasopressin V1b receptortarget
OxytocinVasopressin V2 receptortarget
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneATP-dependent translocase ABCB1transporter
BetamethasoneAromataseenzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneAlbumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
TriamcinoloneCorticosteroid-binding globulincarrier
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneAlbumincarrier
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneATP-dependent translocase ABCB1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneAlbumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
Prednisone11-beta-hydroxysteroid dehydrogenase 1enzyme
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneATP-dependent translocase ABCB1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneOrganic anion transporter 3transporter
HydrocortisoneAldo-keto reductase family 1 member D1enzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
Hydrocortisone11-beta-hydroxysteroid dehydrogenase type 2enzyme
Hydrocortisone11-beta-hydroxysteroid dehydrogenase 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
PrednisoloneCorticosteroid-binding globulincarrier
PrednisoloneCytochrome P450 3A4enzyme
PrednisoloneGlucocorticoid receptortarget
PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
PrednisoloneATP-dependent translocase ABCB1transporter
PrednisoloneAlbumincarrier
RimexoloneCorticosteroid-binding globulincarrier
RimexoloneGlucocorticoid receptortarget
RimexoloneCytochrome P450 3A4enzyme
RimexoloneCytochrome P450 3A5enzyme
RimexoloneSteroid hormone receptor ERR1target
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneATP-dependent translocase ABCB1transporter
DexamethasoneATP-binding cassette sub-family C member 2transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneAlbumincarrier
Dexamethasone11-beta-hydroxysteroid dehydrogenase type 2enzyme
Dexamethasone11-beta-hydroxysteroid dehydrogenase 1enzyme
DexamethasoneOrganic anion transporter 3transporter
FluocortoloneCytochrome P450 3A4enzyme
FluocortoloneCytochrome P450 3A5enzyme
LypressinVasopressin V1a receptortarget
LypressinVasopressin V2 receptortarget
LypressinVasopressin V1b receptortarget
LypressinATP-binding cassette sub-family C member 2transporter
TiratricolThyroid hormone receptor betatarget
TiratricolHepatic sodium/bile acid cotransportertransporter
TiratricolThyroid hormone receptor alphatarget
EtelcalcetideExtracellular calcium-sensing receptortarget
CortisoneCytochrome P450 3A4enzyme
CortisoneCytochrome P450 3A5enzyme
Mecasermin rinfabateInsulin-like growth factor 1 receptortarget
Mecasermin rinfabateInsulin receptortarget
Mecasermin rinfabateCation-independent mannose-6-phosphate receptortarget
OsilodrostatCytochrome P450 11B1, mitochondrialtarget
OsilodrostatCytochrome P450 11B2, mitochondrialtarget
OsilodrostatCytochrome P450 3A4enzyme
OsilodrostatCytochrome P450 2B6enzyme
OsilodrostatCytochrome P450 2D6enzyme
OsilodrostatUDP-glucuronosyltransferase 1A4enzyme
OsilodrostatUDP-glucuronosyltransferase 2B7enzyme
OsilodrostatUDP-glucuronosyltransferase 2B10enzyme
OsilodrostatCytochrome P450 3A5enzyme
OsilodrostatCytochrome P450 1A2enzyme
OsilodrostatCytochrome P450 2C19enzyme
OsilodrostatCytochrome P450 2E1enzyme
OsilodrostatSolute carrier organic anion transporter family member 1B1transporter
OsilodrostatSolute carrier family 22 member 1transporter
OsilodrostatSolute carrier family 22 member 2transporter
OsilodrostatSolute carrier family 22 member 6transporter
OsilodrostatOrganic anion transporter 3transporter
OsilodrostatMultidrug and toxin extrusion protein 1transporter
OsilodrostatUDP-glucuronosyltransferase 1A1enzyme
ElagolixGonadotropin-releasing hormone receptortarget
ElagolixCytochrome P450 3A Subfamilyenzyme
ElagolixCytochrome P450 2D6enzyme
ElagolixCytochrome P450 2C8enzyme
ElagolixATP-dependent translocase ABCB1transporter
ElagolixSolute carrier organic anion transporter family member 1B1transporter
ElagolixUDP-glucuronosyltransferases (UGTs)enzyme
Calcifediol25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
CalcifediolVitamin D3 receptortarget
Calcifediol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
NorethisteroneProgesterone receptortarget
NorethisteroneATP-dependent translocase ABCB1transporter
NorethisteroneCytochrome P450 2C19enzyme
NorethisteroneAlbumincarrier
NorethisteroneSex hormone-binding globulincarrier
NorethisteroneAldo-keto reductase family 1 member C4enzyme
Norethisterone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Norethisterone3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
NorethisteroneAldo-keto reductase family 1 member D1enzyme
NorethisteroneCytochrome P450 3A4enzyme
NorethisteroneCytochrome P450 1A2enzyme
NorethisteroneCytochrome P450 2A6enzyme
NorethisteroneGlucocorticoid receptortarget
NorethisteroneAndrogen receptortarget
EstradiolEstrogen receptortarget
EstradiolNuclear receptor subfamily 1 group I member 2target
EstradiolSex hormone-binding globulincarrier
EstradiolEstrogen receptor betatarget
EstradiolCytochrome P450 1A2enzyme
EstradiolUDP-glucuronosyltransferase 1A1enzyme
EstradiolAlbumincarrier
EstradiolFatty acid-binding protein, intestinalcarrier
EstradiolCytochrome P450 3A4enzyme
EstradiolCytochrome P450 3A5enzyme
EstradiolCytochrome P450 3A7enzyme
EstradiolSolute carrier family 22 member 2transporter
EstradiolSolute carrier family 22 member 3transporter
EstradiolATP-binding cassette sub-family C member 10transporter
EstradiolSolute carrier family 22 member 11transporter
EstradiolBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
EstradiolSolute carrier organic anion transporter family member 1B1transporter
EstradiolATP-dependent translocase ABCB1transporter
EstradiolCytochrome P450 1A1enzyme
EstradiolCytochrome P450 1B1enzyme
EstradiolCytochrome P450 2C19enzyme
EstradiolCytochrome P450 2C8enzyme
EstradiolCytochrome P450 2C9enzyme
EstradiolOrganic anion transporter 3transporter
EstradiolSolute carrier organic anion transporter family member 1B3transporter
EstradiolSolute carrier organic anion transporter family member 1C1transporter
EstradiolNeuronal acetylcholine receptor subunit alpha-4target
EstradiolG-protein coupled estrogen receptor 1target
EstradiolATP synthase subunit atarget
EstradiolBeclin-1target
EstradiolUDP-glucuronosyltransferase 2B15enzyme
EstradiolCatechol O-methyltransferaseenzyme
EstradiolUDP-glucuronosyltransferases (UGTs)enzyme
EstradiolAromataseenzyme
KetoconazoleCytochrome P450 3A4enzyme
KetoconazoleCytochrome P450 2C9enzyme
KetoconazoleCytochrome P450 2C19enzyme
KetoconazoleCytochrome P450 3A5enzyme
KetoconazoleCytochrome P450 1A2enzyme
KetoconazoleCytochrome P450 2C8enzyme
KetoconazoleCytochrome P450 1A1enzyme
KetoconazoleCytochrome P450 2D6enzyme
KetoconazoleBile salt export pumptransporter
KetoconazoleATP-dependent translocase ABCB1transporter
KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
KetoconazoleCytochrome P450 1B1enzyme
KetoconazoleCytochrome P450 2A6enzyme
KetoconazoleCytochrome P450 2B6enzyme
KetoconazoleLanosterol 14-alpha demethylasetarget
KetoconazoleAndrogen receptortarget
KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
KetoconazoleSteroid 21-hydroxylasetarget
KetoconazolePotassium voltage-gated channel subfamily H member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 3target
KetoconazoleUDP-glucuronosyltransferase 1A1enzyme
KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
KetoconazoleCytochrome P450 4F12enzyme
KetoconazoleCytochrome P450 4F2enzyme
KetoconazoleAlbumincarrier
KetoconazoleSex hormone-binding globulincarrier
KetoconazoleAromataseenzyme
KetoconazoleUDP-glucuronosyltransferase 1A7enzyme
KetoconazoleLanosterol 14-alpha demethylasetarget
AbaloparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
RelugolixAlbumincarrier
RelugolixAlpha-1-acid glycoprotein 1carrier
RelugolixATP-dependent translocase ABCB1transporter
RelugolixBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
RelugolixCytochrome P450 3A Subfamilyenzyme
RelugolixCytochrome P450 2C8enzyme
RelugolixCytochrome P450 2B6enzyme
RelugolixGonadotropin-releasing hormone receptortarget
SomatrogonGrowth hormone receptortarget
Somapacitan11-beta-hydroxysteroid dehydrogenase 1enzyme
SomapacitanCytochrome P450 2C12, female-specificenzyme
SomapacitanCytochrome P450 1A2enzyme
SomapacitanCytochrome P450 2C19enzyme
SomapacitanAlbumincarrier
SomapacitanGrowth hormone receptortarget
LinzagolixCytochrome P450 2C8enzyme
LinzagolixGonadotropin-releasing hormone receptortarget
LinzagolixAlbumincarrier
LinzagolixCytochrome P450 2C9enzyme
LinzagolixCytochrome P450 3A4enzyme
LinzagolixSolute carrier organic anion transporter family member 1B1transporter
LinzagolixSolute carrier organic anion transporter family member 1B3transporter
LinzagolixOrganic anion transporter 3transporter
LinzagolixBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
LinzagolixSolute carrier family 22 member 6transporter
LevoketoconazoleCytochrome P450 11B1, mitochondrialtarget
LevoketoconazoleLanosterol 14-alpha demethylasetarget
LevoketoconazoleCytochrome P450 3A4enzyme
LevoketoconazoleCytochrome P450 3A5enzyme
LevoketoconazoleSteroid 21-hydroxylaseenzyme
LevoketoconazoleATP-dependent translocase ABCB1transporter
LevoketoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
LevoketoconazoleCytochrome P450 11B2, mitochondrialtarget
LevoketoconazoleCholesterol side-chain cleavage enzyme, mitochondrialtarget
LevoketoconazoleSolute carrier family 22 member 2transporter
LevoketoconazoleMultidrug and toxin extrusion protein 1transporter
LevoketoconazoleCytochrome P450 2B6enzyme
LevoketoconazoleCytochrome P450 2C8enzyme
LevoketoconazoleCytochrome P450 1A2enzyme
LevoketoconazoleCytochrome P450 7A1enzyme
LevoketoconazoleAromataseenzyme
DasiglucagonGlucagon receptortarget
Lonapegsomatropin11-beta-hydroxysteroid dehydrogenase 1enzyme
LonapegsomatropinGrowth hormone receptortarget
LonapegsomatropinProlactin receptortarget
LonapegsomatropinCytochrome P450 1A2enzyme
LonapegsomatropinCytochrome P450 2C19enzyme
LonapegsomatropinATP-dependent translocase ABCB1transporter
VamoroloneGlucocorticoid receptortarget
VamoroloneCytochrome P450 3A4enzyme
VamoroloneCytochrome P450 3A5enzyme
VamoroloneCytochrome P450 2C8enzyme
VamoroloneUDP-glucuronosyltransferase 1A3enzyme
VamoroloneUDP-glucuronosyltransferase 2B7enzyme
VamoroloneUDP-glucuronosyltransferase 2B17enzyme
VamoroloneMineralocorticoid receptortarget
PalopegteriparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget