Gynecological Antiinfectives and Antiseptics

Name
Gynecological Antiinfectives and Antiseptics
Accession Number
DBCAT002247
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
Ascorbic acidA vitamin used to correct vitamin C deficiency and to increase the intestinal absorption of iron.
OxiconazoleA topical antifungal used to treat a variety of dermatophyte infections.
TerconazoleAn antifungal drug used in the treatment of vulvovaginal candidiasis.
SulfisoxazoleA sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.
Gentian violet cationAn antiseptic violet dye used to prevent various infections, including fungal and bacterial infections.
BendroflumethiazideA diuretic used to suppress lactation and to treat hypertension and edema.
MetolazoneA thiazide-like diuretic used to treat hypertension.
BenzthiazideFor the treatment of high blood pressure and management of edema.
OxytetracyclineA tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
FurazolidoneA drug for the treatment of infectious diarrhea.
ButoconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
NystatinA polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
SulfametopyrazineAn antibiotic used in the treatment or prevention of bacterial infections and malaria.
HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
ChlorothiazideA thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
SulfamethoxazoleAn oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.
ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
DiclofenamideA carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.
CandicidinUsed in the topical treatment of vulvovaginal candidiasis.
SertaconazoleA topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients.
DarunavirA HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
SulfacytineUsed orally in the treatment of acute urinary tract infections.
SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
SulfamethazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
Acetic acidAn antimicrobial agent used to treat susceptible infections of the external auditory canal.
DequaliniumA quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat, as well as vaginal candidiasis.
Lactic acidAn emollient and keratolytic used agent in various cosmetic products and used as an additive in various pharmaceutical products for its antibacterial properties.
Silver sulfadiazineA topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.
SimeprevirA direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
SulfaphenazoleFor the treatment bacterial infections.
MafenideAn antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.
IsoconazoleAn imidazole antifungal used for superficial skin and vaginal infections.
HexetidineAn topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa.
DiiodohydroxyquinolineUsed in the treatment of amoebiasis.
ChlorquinaldolChlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment...
AzanidazoleNot Annotated
FlutrimazoleA topical antifungal used to treat pityriasis capitis and seborrheic dermatitis.
PolicresulenNot Annotated
CarfecillinNot Annotated
ClodantoinNot Annotated
SulfatolamideNot Annotated
PentamycinNot Annotated
ProtiofateNot Annotated
MepartricinA medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.
OmoconazoleNot Annotated
NifuratelA nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infections.
Copper usnateNot Annotated
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
SulfanilamideA sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
SulfadiazineA sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
ChloramphenicolA broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
SulfamethizoleA sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
CyclothiazideCyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either...
SulfacetamideA sulfonamide used to treat inflammatory ocular conditions and acne vulgaris.
Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
NatamycinA macrolide antifungal used to treat fungal infections of the eye.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
SulfapyridineA sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum.
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
TrichlormethiazideUsed in the treatment of oedema (including that associated with heart failure) and hypertension.
KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
CiclopiroxA broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.
ClindamycinA lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
SulfamerazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
InosineA nutritional supplement touted to improve athletic performance and a drug used in vitro as a red blood cell rejuvenator for a unit of red blood cells that will be used in a clinical setting.
ClioquinolAn antifungal cream used to treat a variety of fungal infections.
SulfathiazoleSulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
SulfadimethoxineFor use in the treatment of infections.
Povidone-iodineA topical antiseptic agent used for the treatment and prevention of infection in wounds.
SulfameterLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
OxyquinolineA medication used in combination with other medications to restore vaginal pH.
OctenidineAn antiseptic agent used topically, on mucous membranes, and prior to surgery.
OrnidazoleA nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis.
AcetarsolAn anti infective used to treat a wide variety of infections in the body.
HachimycinNot Annotated
PropenidazoleNot Annotated
FenticonazoleAn imidazole antifungal used to treat a variety of topical fungal infections.
BroxyquinolineNot Annotated
Acetyl sulfisoxazoleAcute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the...
TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
QuinethazoneUsed to treat hypertension.
GlymidineGlycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.
PiretanideA loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin.
AcetazolamideA carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
CyclopenthiazideCyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients...
PhthalylsulfathiazoleA sulfonamide antibacterial indicated in the treatment of gastrointestinal infections.
DapivirineDapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures.
MeticraneMeticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure .
BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
VemurafenibA kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
MethazolamideA carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma.
DorzolamideA carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
BrinzolamideA carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
MitapivatA pyruvate kinase activator used to treat hemolytic anemia in adults with pyruvate kinase (PK) deficiency.
AcetohexamideUsed in the management of diabetes mellitus type 2 (adult-onset).
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
ChlorpropamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
TolazamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
GliclazideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
TolbutamideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
UdenafilA PDE5 inhibitor used to treat erectile dysfunction.
SulthiameA carbonic anhydrase inhibitor used primarily in benign focal epilepsies of childhood that may be useful as an adjunct therapy in a variety of other refractory epilepsies.
FedratinibFedratinib is indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis.[L8090,L47016]
Drugs & Drug Targets
DrugTargetType
Ascorbic acidProlyl 4-hydroxylase subunit alpha-1target
Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 1target
Ascorbic acidHyaluronate lyasetarget
Ascorbic acidDNAtarget
Ascorbic acidXylose isomerasetarget
Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 2target
Ascorbic acidPhytanoyl-CoA dioxygenase, peroxisomaltarget
Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 3target
Ascorbic acidGamma-butyrobetaine dioxygenasetarget
Ascorbic acidDopamine beta-hydroxylasetarget
Ascorbic acidPeptidyl-glycine alpha-amidating monooxygenasetarget
Ascorbic acidProlyl 3-hydroxylase 1target
Ascorbic acid2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2target
Ascorbic acidAlpha-ketoglutarate-dependent dioxygenase alkB homolog 2target
Ascorbic acidProlyl 3-hydroxylase 2target
Ascorbic acidProlyl 3-hydroxylase 3target
Ascorbic acid2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1target
Ascorbic acidEgl nine homolog 2target
Ascorbic acidAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3target
Ascorbic acidLysine-specific demethylase 5Dtarget
Ascorbic acidEgl nine homolog 1target
Ascorbic acidEgl nine homolog 3target
Ascorbic acidTrimethyllysine dioxygenase, mitochondrialtarget
Ascorbic acidTransmembrane prolyl 4-hydroxylasetarget
Ascorbic acidSolute carrier family 23 member 1transporter
Ascorbic acidSolute carrier family 23 member 2transporter
Ascorbic acidSolute carrier family 2, facilitated glucose transporter member 1transporter
Ascorbic acidSolute carrier family 2, facilitated glucose transporter member 3transporter
Ascorbic acidSolute carrier family 2, facilitated glucose transporter member 4transporter
Ascorbic acidSerum albumincarrier
Ascorbic acidThioredoxin reductase 1, cytoplasmicenzyme
OxiconazoleCytochrome P450 51target
OxiconazoleLanosterol synthasetarget
OxiconazoleCytochrome P450 3A4enzyme
OxiconazoleCytochrome P450 2C19enzyme
OxiconazoleNuclear receptor subfamily 1 group I member 2target
TerconazoleCytochrome P450 51target
SulfisoxazoleDihydropteroate synthasetarget
SulfisoxazoleCytochrome P450 2C9enzyme
Gentian violet cationDNAtarget
Gentian violet cationSolute carrier family 22 member 1transporter
BendroflumethiazideSolute carrier family 12 member 3target
BendroflumethiazideCarbonic anhydrase 1target
BendroflumethiazideCarbonic anhydrase 2target
BendroflumethiazideCarbonic anhydrase 4target
BendroflumethiazideCalcium-activated potassium channel subunit alpha-1target
BendroflumethiazideThiopurine S-methyltransferaseenzyme
MetolazoneSolute carrier family 12 member 3target
BenzthiazideSolute carrier family 12 member 3target
BenzthiazideCarbonic anhydrase 1target
BenzthiazideCarbonic anhydrase 2target
BenzthiazideCarbonic anhydrase 4target
BenzthiazideCarbonic anhydrase 9target
BenzthiazideCarbonic anhydrase 12target
BenzthiazideCarbonic anhydrasetarget
Oxytetracycline30S ribosomal protein S4target
Oxytetracycline30S ribosomal protein S9target
Oxytetracycline16S ribosomal RNAtarget
OxytetracyclineSolute carrier family 22 member 6transporter
OxytetracyclineSolute carrier family 22 member 8transporter
OxytetracyclineSolute carrier family 22 member 11transporter
OxytetracyclineSolute carrier family 22 member 7transporter
OxytetracyclineSerum albumincarrier
FurazolidoneDNAtarget
FurazolidoneAmine oxidase [flavin-containing] Benzyme
FurazolidoneAmine oxidase [flavin-containing] Aenzyme
ButoconazoleErgosteroltarget
NystatinErgosteroltarget
NystatinSolute carrier organic anion transporter family member 1B1transporter
NystatinSolute carrier organic anion transporter family member 1B3transporter
SulfametopyrazineDihydropteroate synthetasetarget
HydroflumethiazideSolute carrier family 12 member 1target
HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 4target
HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 2target
HydroflumethiazideCarbonic anhydrase 1target
HydroflumethiazideCarbonic anhydrase 9target
HydroflumethiazideCarbonic anhydrase 12target
HydroflumethiazideSerum albumincarrier
HydroflumethiazideSolute carrier family 22 member 6transporter
HydroflumethiazideSolute carrier family 22 member 8transporter
HydroflumethiazideCarbonic anhydrase 7target
ChlorothiazideSolute carrier family 12 member 3target
ChlorothiazideCarbonic anhydrase 1target
ChlorothiazideCarbonic anhydrase 2target
ChlorothiazideSolute carrier family 22 member 6transporter
SulfamethoxazoleCytochrome P450 2C9enzyme
SulfamethoxazoleSerum albumincarrier
SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
SulfamethoxazoleDihydropteroate synthasetarget
SulfamethoxazoleCytochrome P450 3A4enzyme
SulfamethoxazoleBile salt export pumptransporter
ProbenecidSolute carrier family 22 member 8target
ProbenecidSolute carrier family 22 member 11target
ProbenecidSerum albumincarrier
ProbenecidSolute carrier family 22 member 2transporter
ProbenecidSolute carrier family 22 member 1transporter
ProbenecidCanalicular multispecific organic anion transporter 2transporter
ProbenecidMultidrug resistance-associated protein 4transporter
ProbenecidMultidrug resistance-associated protein 5transporter
ProbenecidMonocarboxylate transporter 2transporter
ProbenecidSolute carrier family 22 member 5transporter
ProbenecidMultidrug resistance-associated protein 6transporter
ProbenecidMultidrug resistance-associated protein 1transporter
ProbenecidSolute carrier organic anion transporter family member 1A2transporter
ProbenecidMonocarboxylate transporter 1transporter
ProbenecidSodium/bile acid cotransportertransporter
ProbenecidSolute carrier family 22 member 6transporter
ProbenecidSolute carrier family 22 member 10transporter
ProbenecidSolute carrier family 22 member 8transporter
ProbenecidCanalicular multispecific organic anion transporter 1transporter
ProbenecidATP-binding cassette sub-family C member 11transporter
ProbenecidSolute carrier family 22 member 11transporter
ProbenecidSolute carrier organic anion transporter family member 1C1transporter
ProbenecidSolute carrier family 22 member 7transporter
ProbenecidSolute carrier family 22 member 6target
ProbenecidPannexin-1target
ProbenecidCytochrome P450 2C8enzyme
ProbenecidCytochrome P450 3A4enzyme
ProbenecidSolute carrier family 22 member 12transporter
ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
ProbenecidTaste receptor type 2 member 16target
ProbenecidUDP-glucuronosyltransferase 1-1enzyme
ProbenecidCytochrome P450 2C9enzyme
EconazoleCytochrome P450 19A1enzyme
EconazoleCytochrome P450 2E1enzyme
EconazoleCytochrome P450 3A4enzyme
EconazoleCytochrome P450 51target
EconazoleNuclear receptor subfamily 1 group I member 2target
DiclofenamideCarbonic anhydrase 1target
DiclofenamideCarbonic anhydrase 4target
DiclofenamideCarbonic anhydrase 2target
DiclofenamideCarbonic anhydrase 7target
DiclofenamideCarbonic anhydrase 3target
CandicidinErgosteroltarget
CandicidinCytochrome P450 3A4enzyme
SertaconazoleCytochrome P450 51target
DarunavirHuman immunodeficiency virus type 1 proteasetarget
DarunavirCytochrome P450 3A4enzyme
DarunavirSolute carrier organic anion transporter family member 1B1transporter
DarunavirP-glycoprotein 1transporter
DarunavirSerum albumincarrier
DarunavirAlpha-1-acid glycoprotein 1carrier
DarunavirCytochrome P450 2D6enzyme
SulfacytineDihydropteroate synthasetarget
SulfadoxineDihydropteroate synthetasetarget
SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
PolythiazideSolute carrier family 12 member 3target
PolythiazideSolute carrier family 22 member 6transporter
PolythiazideSolute carrier family 22 member 8transporter
PolythiazideSerum albumincarrier
SulfamethazineDihydropteroate synthasetarget
SulfamethazineSerum albumincarrier
SulfamethazineArylamine N-acetyltransferaseenzyme
Acetic acidSolute carrier organic anion transporter family member 2B1transporter
Acetic acidMonocarboxylate transporter 1transporter
DequaliniumE3 ubiquitin-protein ligase XIAPtarget
DequaliniumcGMP-gated cation channel alpha-1target
DequaliniumCalcium-activated potassium channel subunit alpha-1target
DequaliniumHTH-type transcriptional regulator QacRtarget
DequaliniumResponse regulator RamRtarget
DequaliniumAcriflavine resistance protein Btransporter
DequaliniumCalmodulintarget
DequaliniumSmall conductance calcium-activated potassium channel protein 3target
DequaliniumProtein kinase Ctarget
DequaliniumAlpha-synucleintarget
DequaliniumL-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligasetarget
Lactic acidBifunctional protein PutAtarget
Lactic acidNimA-related proteintarget
Lactic acidMonocarboxylate transporter 2transporter
Lactic acidSolute carrier organic anion transporter family member 2B1transporter
Lactic acidMonocarboxylate transporter 1transporter
Lactic acidMonocarboxylate transporter 10transporter
Lactic acidSolute carrier organic anion transporter family member 2A1transporter
Lactic acidMonocarboxylate transporter 4transporter
Silver sulfadiazineDNAtarget
SimeprevirNS3 proteasetarget
SimeprevirSerum albumincarrier
SimeprevirCytochrome P450 1A2enzyme
SimeprevirP-glycoprotein 1transporter
SimeprevirSolute carrier organic anion transporter family member 1B1transporter
SimeprevirSolute carrier organic anion transporter family member 1B3transporter
SimeprevirCytochrome P450 3A4enzyme
SimeprevirCanalicular multispecific organic anion transporter 1transporter
SimeprevirATP-binding cassette sub-family G member 2transporter
SimeprevirSolute carrier organic anion transporter family member 2B1transporter
SimeprevirSodium/bile acid cotransportertransporter
SimeprevirBile salt export pumptransporter
SimeprevirNS3/4A proteintarget
SulfaphenazoleCytochrome P450 2C9enzyme
SulfaphenazoleCytochrome P450 2B6enzyme
SulfaphenazoleCytochrome P450 2C8enzyme
SulfaphenazoleCytochrome P450 2D6enzyme
SulfaphenazoleDihydropteroate synthasetarget
MafenideCarbonic anhydrase 6target
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
ClotrimazoleErgosteroltarget
SulfanilamideDihydropteroate synthasetarget
SulfadiazineCytochrome P450 2C9enzyme
SulfadiazineDihydropteroate synthetasetarget
SulfadiazineCytochrome P450 2C8enzyme
SulfadiazineCytochrome P450 3A4enzyme
ChloramphenicolComplement decay-accelerating factortarget
ChloramphenicolDr hemagglutinin structural subunittarget
ChloramphenicolCytochrome P450 2C19enzyme
ChloramphenicolCytochrome P450 3A4enzyme
ChloramphenicolCytochrome P450 3A5enzyme
ChloramphenicolCytochrome P450 3A7enzyme
ChloramphenicolSolute carrier family 22 member 6transporter
Chloramphenicol50S ribosomal protein L16target
ChloramphenicolChloramphenicol acetyltransferase 3enzyme
ChloramphenicolChloramphenicol acetyltransferaseenzyme
ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
SulfamethizoleDihydropteroate synthasetarget
SulfamethizoleSerum albumincarrier
SulfamethizoleCytochrome P450 2C9enzyme
CyclothiazideSodium/potassium-transporting ATPase subunit gammatarget
CyclothiazideCarbonic anhydrase 1target
CyclothiazideCarbonic anhydrase 2target
CyclothiazideSolute carrier family 22 member 6transporter
CyclothiazideSecreted frizzled-related protein 4target
CyclothiazideCarbonic anhydrasetarget
SulfacetamideDihydropteroate synthasetarget
SulfacetamideDihydropteroate synthase type-1target
SulfacetamideFolic acid synthesis protein FOL1target
Amphotericin BErgosteroltarget
NatamycinErgosteroltarget
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideSodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 22 member 8transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
SulfapyridineDihydropteroate synthase type-1target
SulfapyridineCytochrome P450 2C9enzyme
MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
MetronidazoleCytochrome P450 2C9enzyme
MetronidazoleCytochrome P450 3A4enzyme
MetronidazoleCytochrome P450 2C8enzyme
MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
MetronidazoleAnaerobic bacterial DNAtarget
MetronidazoleProtozoal DNAtarget
MetronidazoleP-glycoprotein 1transporter
MetronidazoleCytochrome P450 2A6enzyme
MetronidazoleCytochrome P450 3A5enzyme
MetronidazoleCytochrome P450 3A7enzyme
HydrochlorothiazideSolute carrier family 12 member 3target
HydrochlorothiazideSolute carrier family 22 member 6transporter
HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
HydrochlorothiazideSerum albumincarrier
HydrochlorothiazideSolute carrier family 22 member 11transporter
HydrochlorothiazideMultidrug resistance-associated protein 4transporter
HydrochlorothiazideSolute carrier family 22 member 8transporter
TioconazoleLanosterol 14-alpha demethylasetarget
TioconazoleCytochrome P450 19A1enzyme
TioconazoleCytochrome P450 2C19enzyme
TioconazoleCytochrome P450 2E1enzyme
TioconazoleCytochrome P450 3A4enzyme
TioconazoleCytochrome P450 51target
TrichlormethiazideSolute carrier family 12 member 3target
TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1target
TrichlormethiazideCarbonic anhydrase 4target
TrichlormethiazideCarbonic anhydrase 2target
TrichlormethiazideCarbonic anhydrase 1target
TrichlormethiazideThiopurine S-methyltransferaseenzyme
KetoconazoleCytochrome P450 3A4enzyme
KetoconazoleCytochrome P450 2C9enzyme
KetoconazoleCytochrome P450 2C19enzyme
KetoconazoleCytochrome P450 3A5enzyme
KetoconazoleCytochrome P450 1A2enzyme
KetoconazoleCytochrome P450 2C8enzyme
KetoconazoleCytochrome P450 1A1enzyme
KetoconazoleCytochrome P450 2D6enzyme
KetoconazoleBile salt export pumptransporter
KetoconazoleP-glycoprotein 1transporter
KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
KetoconazoleCytochrome P450 1B1enzyme
KetoconazoleCytochrome P450 2A6enzyme
KetoconazoleCytochrome P450 2B6enzyme
KetoconazoleLanosterol 14-alpha demethylasetarget
KetoconazoleAndrogen receptortarget
KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
KetoconazoleSteroid 21-hydroxylasetarget
KetoconazolePotassium voltage-gated channel subfamily H member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 3target
KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
KetoconazoleCytochrome P450 4F12enzyme
KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
KetoconazoleSerum albumincarrier
KetoconazoleSex hormone-binding globulincarrier
KetoconazoleCytochrome P450 19A1enzyme
KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
CiclopiroxSodium/potassium-transporting ATPase subunit alpha-1target
ClindamycinCytochrome P450 3A4enzyme
ClindamycinCytochrome P450 3A5enzyme
ClindamycinAlpha-1-acid glycoprotein 1carrier
ClindamycinP-glycoprotein 1transporter
Clindamycin50S ribosomal protein L1target
SulfamerazineDihydropteroate synthasetarget
SulfamerazineSerum albumincarrier
InosinePurine nucleoside phosphorylasetarget
InosineIAG-nucleoside hydrolasetarget
InosinePurine nucleoside phosphorylase DeoD-typetarget
InosineXanthine dehydrogenase/oxidaseenzyme
InosineSolute carrier family 28 member 3transporter
SulfathiazoleDihydropteroate synthetasetarget
SulfathiazoleCytochrome P450 19A1enzyme
SulfadimethoxineCytochrome P450 2C9enzyme
SulfadimethoxineSerum albumincarrier
SulfameterDihydropteroate synthasetarget
Acetyl sulfisoxazoleDihydropteroate synthasetarget
Acetyl sulfisoxazoleCytochrome P450 2C9enzyme
TinidazoleCytochrome P450 3A4enzyme
TinidazoleDNAtarget
TinidazoleBile salt export pumptransporter
QuinethazoneCarbonic anhydrase 1target
QuinethazoneCarbonic anhydrase 2target
QuinethazoneSolute carrier family 12 member 1target
QuinethazoneSolute carrier family 12 member 2target
QuinethazoneSolute carrier family 12 member 3target
GlymidineATP-sensitive inward rectifier potassium channel 1target
GlymidineATP-binding cassette sub-family C member 8target
PiretanideSolute carrier family 12 member 1target
AcetazolamideCarbonic anhydrase 1target
AcetazolamideAquaporin-1target
AcetazolamideCarbonic anhydrase 14target
AcetazolamideSolute carrier family 22 member 6transporter
AcetazolamideCarbonic anhydrase 2target
AcetazolamideCarbonic anhydrase 3target
AcetazolamideCarbonic anhydrase 4target
AcetazolamideCytochrome P450 3A4enzyme
AcetazolamideCarbonic anhydrase 7target
AcetazolamideCarbonic anhydrase 12target
DapivirineGag-Pol polyproteintarget
BosentanEndothelin B receptortarget
BosentanEndothelin-1 receptortarget
BosentanCytochrome P450 3A4enzyme
BosentanCytochrome P450 2C9enzyme
BosentanBile salt export pumptransporter
TamsulosinAlpha-1A adrenergic receptortarget
TamsulosinAlpha-1D adrenergic receptortarget
TamsulosinAlpha-1B adrenergic receptortarget
TamsulosinAlpha-1-acid glycoprotein 1carrier
TamsulosinCytochrome P450 2D6enzyme
TamsulosinCytochrome P450 3A4enzyme
VemurafenibSerum albumincarrier
VemurafenibAlpha-1-acid glycoprotein 1carrier
VemurafenibCytochrome P450 1A2enzyme
VemurafenibCytochrome P450 2D6enzyme
VemurafenibCytochrome P450 3A4enzyme
VemurafenibSerine/threonine-protein kinase B-raftarget
VemurafenibMultidrug resistance-associated protein 1transporter
VemurafenibATP-binding cassette sub-family G member 2transporter
VemurafenibCytochrome P450 2C9enzyme
VemurafenibCytochrome P450 2C8enzyme
VemurafenibCytochrome P450 2B6enzyme
VemurafenibP-glycoprotein 1transporter
MethazolamideCarbonic anhydrase 1target
MethazolamideSolute carrier family 22 member 6transporter
MethazolamideCarbonic anhydrase 4target
MethazolamideCarbonic anhydrase 2target
MethazolamideCarbonic anhydrase 7target
MethazolamideCarbonic anhydrase 3target
DorzolamideCarbonic anhydrase 2target
DorzolamideCarbonic anhydrase 1target
DorzolamideCarbonic anhydrase 4target
DorzolamideCytochrome P450 2C9enzyme
DorzolamideCarbonic anhydrase 3target
DorzolamideCytochrome P450 2B1enzyme
DorzolamideCytochrome P450 2E1enzyme
DorzolamideCytochrome P450 3A2enzyme
BrinzolamideCarbonic anhydrase 1target
BrinzolamideCarbonic anhydrase 2target
BrinzolamideCytochrome P450 3A4enzyme
BrinzolamideCarbonic anhydrase 5A, mitochondrialtarget
BrinzolamideCarbonic anhydrase 4target
BrinzolamideCarbonic anhydrase 3target
BrinzolamideCytochrome P450 2A6enzyme
BrinzolamideCytochrome P450 2B6enzyme
BrinzolamideCytochrome P450 2C8enzyme
BrinzolamideCytochrome P450 2C9enzyme
MitapivatCytochrome P450 3A4enzyme
MitapivatCytochrome P450 2B6enzyme
MitapivatCytochrome P450 2C8enzyme
MitapivatCytochrome P450 2C9enzyme
MitapivatCytochrome P450 2C19enzyme
MitapivatUDP-glucuronosyltransferase 1-1enzyme
MitapivatP-glycoprotein 1transporter
MitapivatCytochrome P450 1A2enzyme
MitapivatPyruvate kinase PKLRtarget
MitapivatCytochrome P450 19A1target
AcetohexamideATP-sensitive inward rectifier potassium channel 1target
AcetohexamideCarbonyl reductase [NADPH] 1enzyme
AcetohexamideSerum albumincarrier
AcetohexamideCytochrome P450 2C9enzyme
ValdecoxibProstaglandin G/H synthase 2target
ValdecoxibCytochrome P450 2C9enzyme
ValdecoxibCytochrome P450 3A4enzyme
ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
ValdecoxibCarbonic anhydrase 2target
ValdecoxibCarbonic anhydrase 3target
ChlorpropamideATP-binding cassette sub-family C member 8target
ChlorpropamideSolute carrier family 15 member 1transporter
ChlorpropamideSolute carrier family 15 member 2transporter
ChlorpropamideSolute carrier family 22 member 6transporter
ChlorpropamideCytochrome P450 2C9enzyme
ChlorpropamideCytochrome P450 2C19enzyme
ChlorpropamideProstaglandin G/H synthase 1enzyme
TolazamideSulfonylurea receptor 1, Kir6.2target
TolazamideCytochrome P450 2C9enzyme
GliclazideATP-binding cassette sub-family C member 8target
GliclazideSerum albumincarrier
GliclazideVascular endothelial growth factor Atarget
GliclazideCytochrome P450 2C9enzyme
GliclazideCytochrome P450 2C19enzyme
TolbutamideATP-sensitive inward rectifier potassium channel 1target
TolbutamideCytochrome P450 2C19enzyme
TolbutamideCytochrome P450 2C9enzyme
TolbutamideCytochrome P450 2C8enzyme
TolbutamideATP-binding cassette sub-family C member 8target
TolbutamideSolute carrier family 15 member 1transporter
TolbutamideSolute carrier organic anion transporter family member 1A2transporter
TolbutamideSolute carrier family 15 member 2transporter
TolbutamideSolute carrier family 22 member 6transporter
TolbutamideSolute carrier organic anion transporter family member 2B1transporter
TolbutamideCytochrome P450 2C18enzyme
TolbutamideSerum albumincarrier
UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
UdenafilCytochrome P450 3A4enzyme
UdenafilCytochrome P450 3A5enzyme
SulthiameCarbonic anhydrase 2target
FedratinibP-glycoprotein 1transporter
FedratinibATP-binding cassette sub-family G member 2transporter
FedratinibSolute carrier organic anion transporter family member 1B1transporter
FedratinibSolute carrier organic anion transporter family member 1B3transporter
FedratinibPOU domain, class 2, transcription factor 2transporter
FedratinibMultidrug and toxin extrusion protein 1transporter
FedratinibMultidrug and toxin extrusion protein 2transporter
FedratinibCytochrome P450 3A4enzyme
FedratinibCytochrome P450 2C19enzyme
FedratinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
FedratinibTyrosine-protein kinase JAK2target
FedratinibReceptor-type tyrosine-protein kinase FLT3target
FedratinibTyrosine-protein kinase JAK1target
FedratinibCytochrome P450 2D6enzyme