- Accession Number
Hydrocarbon rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.
Drug Drug Description Phylloquinone A fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. Sennosides A laxative used to treat constipation. Menadione The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. Atovaquone An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. Mitoxantrone A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis. Nanaomycin D Not Available Duroquinone Not Available Geldanamycin Not Available Flaviolin Not Available Dibromothymoquinone At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. At higher concentrations, it acts as an electron acceptor, intercepting electrons either... Lawsone Not Available Dantron A drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx. Banoxantrone For the treatment of various forms of cancer. Mitoquinone Investigated for use/treatment in hepatitis (viral, C) and parkinson's disease. Tanespimycin Investigated for use/treatment in leukemia (myeloid) and solid tumors. Retaspimycin Investigated for use/treatment in gastric cancer, lung cancer, and multiple myeloma. Porfiromycin Investigated for use/treatment in head and neck cancer. Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. BW-A 58C BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy metabolite in man in vivo and also in human... 2,3-Dimethyl-1,4-naphthoquinone Not Available Emodin Emodin has been investigated for the treatment of Polycystic Kidney. Quinalizarin Not Available Ubiquinone Q1 Not Available Ubiquinone Q2 Not Available Idebenone An analogue of ubiquinone used for the treatment of visual impairment in adolescent and adult patients with Leber’s Hereditary Optic Neuropathy (LHON). Ubidecarenone A cofactor found in various dietary supplements. Triethoxycaprylylsilane Not Annotated Ubiquinol Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human... Vatiquinone Vatiquinone has been investigated for the treatment and prevention of Retinopathy, Rett Syndrome, Genetic Disease, Noise-induced Hearing Loss, and Methylmalonic Aciduria and Homocystinuria,Cblc Type. Lapachone Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell. Diacerein An slow-onset anthraquinone IL-1 inhibitor used in the treatment of degenerative joint diseases like osteoarthritis. Menatetrenone A form of vitamin K2 which is used in the treatment of osteoporosis to stimulate osteogenesis. Napabucasin Napabucasin has been investigated for the treatment of Colorectal Carcinoma. Antroquinonol Antroquinonol has been used in trials studying the treatment of Hyperlipidemias, Non-small Cell Lung Cancer, and Non-small Cell Lung Cancer Stage IV. Alvespimycin Investigated for use as an antineoplastic agent for solid tumors, advanced solid tumours or acute myeloid leukaemia. TU-100 TU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease, Rectal Sensation, and Gastric Emptying, among others. Apaziquone Apaziquone has been investigated for the treatment of Bladder Cancer and Bladder Neoplasms. IPI-493 IPI-493 has been used in trials studying the treatment of Advanced Malignancies. Menaquinone 7 Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children). Rhein No approved indication. Iprazochrome Not Annotated Carboquone Not Annotated Naftazone A naphthoquinone derivative indicated in the treatment of varicose veins, hemorrhoids, and superficial thrombophlebitis. Menaquinone 6 Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2). Menaquinone Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists). Alloin Not Annotated Ochromycinone Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis). 2,3-dichloro-5,6-dicyanobenzoquinone Not Annotated Senna leaf A stimulant laxative indicated in the treatment of occasional constipation. Menadione bisulfite Not Annotated Thymoquinone Thymoquinone is a natural compound with widespread protective effects, including anti-oxidative, anti-inflammatory, immunomodulatory, anti-cancer, and anti-microbial. Plumbagin Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways. Sepantronium Sepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and causes broad-range apoptosis. Diaziquone Not Annotated Visometin cation Not Annotated
- Drugs & Drug Targets