- Accession Number
Hydrocarbon rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.
Drug Drug Description Menadione The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. Phylloquinone A fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. Atovaquone An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. Mitoxantrone A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis. Nanaomycin D Not Available Duroquinone Not Available Geldanamycin Not Available Dibromothymoquinone At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. At higher concentrations, it acts as an electron acceptor, intercepting electrons either... Lawsone Not Available Dantron Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity. Banoxantrone For the treatment of various forms of cancer. Mitoquinone Investigated for use/treatment in hepatitis (viral, C) and parkinson's disease. Tanespimycin Investigated for use/treatment in leukemia (myeloid) and solid tumors. Retaspimycin Investigated for use/treatment in gastric cancer, lung cancer, and multiple myeloma. Porfiromycin Investigated for use/treatment in head and neck cancer. Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. BW-A 58C BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy metabolite in man in vivo and also in human... 2,3-Dimethyl-1,4-naphthoquinone Not Available Ubiquinone Q2 Not Available Idebenone An analogue of ubiquinone used for the treatment of visual impairment in adolescent and adult patients with Leber’s Hereditary Optic Neuropathy (LHON). Ubidecarenone A cofactor found in various dietary supplements. Triethoxycaprylylsilane Not Annotated Ubiquinol Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human... Sennosides A laxative used to treat constipation. Vatiquinone Vatiquinone has been investigated for the treatment and prevention of Retinopathy, Rett Syndrome, Genetic Disease, Noise-induced Hearing Loss, and Methylmalonic Aciduria and Homocystinuria,Cblc Type. Diacerein An slow-onset anthraquinone IL-1 inhibitor used in the treatment of degenerative joint diseases like osteoarthritis. Menatetrenone A form of vitamin K2 which is used in the treatment of osteoporosis to stimulate osteogenesis. Antroquinonol Antroquinonol has been used in trials studying the treatment of Hyperlipidemias, Non-small Cell Lung Cancer, and Non-small Cell Lung Cancer Stage IV. Alvespimycin Investigated for use as an antineoplastic agent for solid tumors, advanced solid tumours or acute myeloid leukaemia. TU-100 TU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease, Rectal Sensation, and Gastric Emptying, among others. Apaziquone Apaziquone has been investigated for the treatment of Bladder Cancer and Bladder Neoplasms. IPI-493 IPI-493 has been used in trials studying the treatment of Advanced Malignancies. Menaquinone 7 Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children). Rhein No approved indication. Iprazochrome Not Annotated Carboquone Not Annotated Naftazone A naphthoquinone derivative indicated in the treatment of varicose veins, hemorrhoids, and superficial thrombophlebitis. Menadiol diphosphate Not Annotated Emodin Emodin has been investigated for the treatment of Polycystic Kidney. Lapachone Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell. Menaquinone 6 Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2). Menaquinone Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists). Napabucasin Napabucasin has been investigated for the treatment of Colorectal Carcinoma. Alloin Not Annotated Frangula purshiana bark Not Annotated Flaviolin Not Available Quinalizarin Not Available Ubiquinone Q1 Not Available Ochromycinone Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis). 2,3-dichloro-5,6-dicyanobenzoquinone Not Annotated Menadione bisulfite Not Annotated Thymoquinone Thymoquinone is a natural compound with widespread protective effects, including anti-oxidative, anti-inflammatory, immunomodulatory, anti-cancer, and anti-microbial.
- Drugs & Drug Targets