Dry Eye Syndrome (DES)

Also known as: Dry Eye Syndrome / Dry Eye Disease / Dry Eye Disease (DED) / Dry Eye Syndromes / Tear film insufficiency, NOS / (Dry eye syndrome) or (tear film insufficiency) or (gritty eye) / Tear film insufficiency (disorder) / Dry eye / Dry eyes (finding) / Eyes dry / Dry eye NOS / Dryness of eyes / Dry eye (finding) / Dry eyes / Eye dryness

DrugDrug NameDrug Description
DB11105BenzalkoniumAn antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products.
DB15649CarbomerNot Annotated
DB15919DiquafosolA medication indicated to treat dry eyes associated with keratoconjunctival disorders.
DB00840Hydroxypropyl celluloseA cellulose ether used to treat dry eyes.
DB11611LifitegrastA medication used to treat dry eye disease.
DB14596Loteprednol etabonateA corticosteroid used to treat allergic conjunctivitis as well as inflammation and pain after ocular surgery.
DB11228MethylcelluloseA compound used as a bulk forming laxative and is not an approved medication.
DB09287Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
DrugDrug NamePhaseStatusCount
DB00083Botulinum toxin type A1Completed1
DB15649Carbomer1Active Not Recruiting1
DB09301Chondroitin sulfate1Active Not Recruiting1
DB09301Chondroitin sulfate1Completed1
DB00091Cyclosporine1Completed1
DB15919Diquafosol1Completed1
DB08818Hyaluronic acid1Active Not Recruiting1
DB08818Hyaluronic acid1Completed1
DB11075Hypromellose1Active Not Recruiting1
DB12373Isunakinra1Completed1
DB01183Naloxone1Recruiting1
DB12320Palovarotene1Completed1
DB11077Polyethylene glycol 4001Completed2
DB01839Propylene glycol1Completed2
DB11656Rebamipide1Completed1
DB12058Recoflavone1Completed1
DB11253Xanthan gum1Completed1
DB11059Carboxymethylcellulose1 / 2Recruiting1
DB00091Cyclosporine1 / 2Completed1
DB09462Glycerin1 / 2Recruiting1
DB08818Hyaluronic acid1 / 2Recruiting1
DB11075Hypromellose1 / 2Recruiting1
DB11062Octisalate1 / 2Completed1
DB09535Octocrylene1 / 2Completed1
DB08895Tofacitinib1 / 2Completed1
DB09321Zinc oxide1 / 2Completed1
DB06151Acetylcysteine2Completed1
DB00443Betamethasone2Recruiting2
DB12792Boscalid2Completed1
DB05041Brivudine2Completed1
DB00963Bromfenac2Completed1
DB15649Carbomer2Recruiting1
DB13926Cenegermin2Completed2
DB00091Cyclosporine2Completed3
DB00091Cyclosporine2Recruiting1
DB00091Cyclosporine2Terminated2
DB01234Dexamethasone2Completed1
DB06781Difluprednate2Completed1
DB00975Dipyridamole2Unknown Status1
DB15919Diquafosol2Completed2
DB05265Ecabet2Completed2
DB08818Hyaluronic acid2Completed2
DB11075Hypromellose2Recruiting1
DB11611Lifitegrast2Recruiting1
DB14596Loteprednol etabonate2Completed1
DB12041Mapracorat2Completed1
DB01024Mycophenolic acid2Recruiting1
DB00704Naltrexone2Completed1
DB12620Nerve Growth Factor2Completed1
DB11062Octisalate2Completed3
DB11062Octisalate2Unknown Status1
DB09535Octocrylene2Completed3
DB09535Octocrylene2Unknown Status1
DB12017Ozagrel2Completed4
DB00085Pancrelipase2Active Not Recruiting1
DB11077Polyethylene glycol 4002Completed1
DB01839Propylene glycol2Completed1
DB11656Rebamipide2Completed3
DB12058Recoflavone2Completed1
DB16688Reproxalap2Completed2
DB09154Sodium citrate2Completed1
DB12003Thymosin beta-42Completed1
DB08895Tofacitinib2Completed1
DB09321Zinc oxide2Completed3
DB09321Zinc oxide2Unknown Status1
DB00091Cyclosporine2 / 3Completed1
DB05265Ecabet2 / 3Completed1
DB09567Olive oil2 / 3Completed1
DB11133Omega-3 fatty acids2 / 3Completed1
DB16688Reproxalap2 / 3Recruiting1
DB12003Thymosin beta-42 / 3Completed1
DB11693Voclosporin2 / 3Completed1
DB00963Bromfenac3Completed1
DB11059Carboxymethylcellulose3Completed6
DB00091Cyclosporine3Active Not Recruiting1
DB00091Cyclosporine3Completed10
DB15919Diquafosol3Completed6
DB00736Esomeprazole3Completed1
DB16169Fonadelpar3Completed1
DB09462Glycerin3Completed3
DB08818Hyaluronic acid3Completed3
DB08818Hyaluronic acid3Not Yet Recruiting1
DB08818Hyaluronic acid3Unknown Status1
DB11075Hypromellose3Completed1
DB12373Isunakinra3Completed1
DB11611Lifitegrast3Completed4
DB14596Loteprednol etabonate3Completed2
DB00959Methylprednisolone3Completed1
DB11062Octisalate3Completed1
DB09535Octocrylene3Completed1
DB11077Polyethylene glycol 4003Completed4
DB11077Polyethylene glycol 4003Not Yet Recruiting1
DB01839Propylene glycol3Completed2
DB11078Propylene glycol3Completed2
DB01839Propylene glycol3Not Yet Recruiting1
DB11656Rebamipide3Completed3
DB16688Reproxalap3Recruiting1
DB12441Tavilermide3Completed1
DB12003Thymosin beta-43Active Not Recruiting1
DB12003Thymosin beta-43Completed1
DB01273Varenicline3Completed1
DB09321Zinc oxide3Completed1
DB00207Azithromycin4Completed1
DB00207Azithromycin4Recruiting1
DB00963Bromfenac4Completed1
DB11059Carboxymethylcellulose4Completed12
DB09301Chondroitin sulfate4Completed1
DB01285Corticotropin4Completed1
DB00091Cyclosporine4Completed7
DB00091Cyclosporine4Not Yet Recruiting2
DB00091Cyclosporine4Recruiting2
DB00091Cyclosporine4Unknown Status1
DB00091Cyclosporine4Withdrawn1
DB01234Dexamethasone4Completed2
DB01234Dexamethasone4Not Yet Recruiting1
DB01234Dexamethasone4Recruiting4
DB15919Diquafosol4Not Yet Recruiting1
DB00254Doxycycline4Recruiting1
DB00324Fluorometholone4Recruiting1
DB04077Glycerin4Completed1
DB09462Glycerin4Completed5
DB08818Hyaluronic acid4Active Not Recruiting1
DB08818Hyaluronic acid4Completed5
DB08818Hyaluronic acid4Not Yet Recruiting1
DB08818Hyaluronic acid4Unknown Status1
DB11075Hypromellose4Completed1
DB00465Ketorolac4Completed1
DB00654Latanoprost4Completed1
DB01137Levofloxacin4Completed1
DB11611Lifitegrast4Recruiting1
DB11611Lifitegrast4Withdrawn1
DB14596Loteprednol etabonate4Completed2
DB14596Loteprednol etabonate4Withdrawn1
DB11057Mineral oil4Completed2
DB11062Octisalate4Completed2
DB09535Octocrylene4Completed2
DB09567Olive oil4Completed1
DB11058Petrolatum4Completed2
DB11077Polyethylene glycol 4004Completed6
DB11063Polysorbate 804Completed1
DB11061Povidone4Completed1
DB00860Prednisolone4Completed1
DB15566Prednisolone acetate4Completed1
DB15566Prednisolone acetate4Recruiting1
DB01839Propylene glycol4Completed4
DB11078Propylene glycol4Completed2
DB11656Rebamipide4Completed1
DB00864Tacrolimus4Completed1
DB00864Tacrolimus4Recruiting1
DB00287Travoprost4Completed1
DB09321Zinc oxide4Completed2
DB11059CarboxymethylcelluloseNot AvailableCompleted4
DB00091CyclosporineNot AvailableCompleted3
DB00091CyclosporineNot AvailableUnknown Status1
DB01234DexamethasoneNot AvailableCompleted1
DB01234DexamethasoneNot AvailableUnknown Status1
DB09255DextranNot AvailableNot Yet Recruiting1
DB01075DiphenhydramineNot AvailableCompleted1
DB15919DiquafosolNot AvailableCompleted1
DB00254DoxycyclineNot AvailableWithdrawn1
DB09462GlycerinNot AvailableCompleted4
DB08818Hyaluronic acidNot AvailableCompleted1
DB08818Hyaluronic acidNot AvailableNot Yet Recruiting1
DB00741HydrocortisoneNot AvailableCompleted1
DB11075HypromelloseNot AvailableNot Yet Recruiting1
DB14596Loteprednol etabonateNot AvailableUnknown Status1
DB11057Mineral oilNot AvailableUnknown Status1
DB11133Omega-3 fatty acidsNot AvailableActive Not Recruiting1
DB09539Omega-3-acid ethyl estersNot AvailableActive Not Recruiting1
DB09539Omega-3-acid ethyl estersNot AvailableCompleted1
DB11058PetrolatumNot AvailableUnknown Status1
DB11077Polyethylene glycol 400Not AvailableCompleted7
DB11077Polyethylene glycol 400Not AvailableNot Yet Recruiting1
DB11063Polysorbate 80Not AvailableCompleted2
DB11060Polyvinyl alcoholNot AvailableCompleted1
DB01839Propylene glycolNot AvailableCompleted1
DB11078Propylene glycolNot AvailableCompleted6
DB01839Propylene glycolNot AvailableNot Yet Recruiting1
DB00759TetracyclineNot AvailableWithdrawn1
DB00684TobramycinNot AvailableUnknown Status1
DB00162Vitamin ANot AvailableNot Yet Recruiting1
DB00163Vitamin ENot AvailableNot Yet Recruiting1