Bacterial Vaginosis (BV) (DBCOND0071525)

Identifiers

Synonyms
Vaginosis, Bacterial / Bacterial Vaginosis / Vaginosis bacterial / Bacterial vaginosis (disorder) / Vaginitis bacterial / Vaginosis bacterial NOS / Vaginitis bacterial NOS / Non-specific vaginitis

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Clindamycin
A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
Clotrimazole
A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
Dequalinium
A quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat, as well as vaginal candidiasis.
Ketoconazole
A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
Lidocaine
A local anesthetic used in a wide variety of superficial and invasive procedures.
Metronidazole
A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
Secnidazole
A nitroimidazole antibiotic used to treat bacterial vaginosis.
Tinidazole
A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02197182
LUXSOL(TM) Topical Cream for the Treatment of Symptomatic Bacterial Vaginosis; A Proof of Concept Studytreatment0terminated
NCT01322971
Efficacy Study of Preconception Treatment of an Asymptomatic Bacterial Infection in an Infertility PopulationtreatmentNot Availableterminated
NCT01055106
Dose Ranging Study of Metronidazole Vaginal Gel in the Treatment of Bacterial Vaginosistreatment2completed
NCT02641717
Validity of Patient-Collected Wet MountsNo drug interventionsdiagnosticNot Availablecompleted
NCT00153517
Maternal Effects of Bacterial Vaginosis (BV) Treatment in Pregnancytreatment2completed
NCT05649735
EFFICACY AND SAFETY OF OVA AND LAVAGE MEDICAL DEVICES IN THE TREATMENT OF NON-SPECIFIC VULVOVAGINITISNo drug interventionstreatmentNot Availablecompleted
NCT02139839
Exploratory Study to Evaluate the Effects of the Probiotics L. Rhamnosus GR-1 and L. Reuteri RC-14No drug interventionstreatment0completed
NCT02392026
Safety and Tolerability of Metronidazole Gel 1.3%treatment4completed
NCT02272231
Pathogenesis of Bacterial Vaginosis in Women Who Have Sex With WomenNo drug interventionsNot AvailableNot Availablecompleted
NCT02687789
Safety, Tolerability and Efficacy of Vaginal Suppository WO3191 in the Post-treatment of Bacterial VaginosisNo drug interventionspreventionNot Availablecompleted
NCT03943823
Postmenopausal Pessary Users: Estrogen Versus Trimosantreatment4terminated
NCT02558179
Diagnosing Bacterial Vaginosis/Vaginitis (BV) Using the Gynecologene Test MethodNo drug interventionsNot AvailableNot Availableunknown_status
NCT00484653
Identification and Impact of Vaginal Flora Anomalies Among Pregnant WomanNo drug interventionsdiagnosticNot Availablecompleted
NCT04171947
Vaginal Ovule With Flavonoid Tea Extract for the Correction of Imbalance in the Vaginal EnvironmentNo drug interventionstreatmentNot Availablecompleted
NCT02860845
Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infectionstreatment4completed
NCT03500107
Use of Blue Light Emitting Diode in the Treatment of Women With Bacterial Vaginosis: a Clinical TrialNo drug interventionstreatmentNot Availablerecruiting
NCT00491270
Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm DeliveryNo drug interventionsdiagnostic3unknown_status
NCT03134924
Vaginal Practices in Human Immunodeficiency Virus (HIV) Positive Women in Zambia, a Bio-Behavioral Intervention "WASH-2"No drug interventionspreventionNot Availablecompleted
NCT01153958
Colposeptine for the Treatment of Bacterial Vaginosistreatment4terminated
NCT01448291
Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkerstreatment4unknown_status
NCT02314429
Trial Evaluating the Safety of a Lactate Releasing Vaginal Ring for the Prophylaxis of Bacterial VaginosisNo drug interventionsNot Available1completed
NCT01293643
A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077)treatment3completed
NCT04989543
Study of the Composition and Bacterial Diversity of the Vaginal Microbiota in Healthy Versus Pathological Conditions (Bacterial Vaginosis) Using a Targeted Metagenomic Approach (RNA 16s)No drug interventionsdiagnosticNot Availablecompleted
NCT02042287
Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosistreatment4completed
NCT00334633
Treatment of Bacterial Vaginosis (BV) With Tinidazoletreatment4completed
NCT00682851
A Validation Study of Genzyme Diagnostics OSOM Trichomonas Rapid Test and BVBlue TestNo drug interventionsNot AvailableNot Availablecompleted
NCT00741845
Prevention of Persistence of Bacterial Vaginosistreatment3terminated
NCT02418845
A Phase 3 Study of SYM-1219 Treatment of Women and Post-Menarchal Adolescent Girls With Bacterial Vaginosistreatment3completed
NCT02709005
Safety and Efficacy of 5% Monolaurin Vaginal Gel Administered Intravaginally for the Treatment of Bacterial Vaginosistreatment2completed
NCT03762083
Clinical Performance of a Vaginal Pessary (pHyph) in Bacterial VaginosisNo drug interventionstreatmentNot Availablecompleted
NCT05587283
Safety, Tolerability, and Acceptability Study of Intravaginal Administration of LABTHERA-001 Capsules in Healthy Womenother1recruiting
NCT04771728
A Prospective, Randomized Controlled Study of the Probiotics as Adjuvant Treatment for Bacterial Vaginosistreatment4recruiting
NCT05963711
The Genital Microbiome of Male Partners of Women With Recurrent BV Undergoing Vaginal Microbiome TransplantationNo drug interventionsdiagnosticNot Availablerecruiting
NCT01841411
Role of N-Acetylcysteine in Treatment of Bacterial Vaginosistreatment4unknown_status
NCT05666778
Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIsNo drug interventionsprevention2active_not_recruiting
NCT03769688
Safety and Efficacy of Vaginal Microbiota Transplant (VMT) in Women With Bacterial Vaginosis (BV)basic_science1withdrawn
NCT01558388
Probiotic Versus Placebo as Adjuvant for Bacterial Vaginosis Treatment During Pregnancytreatment4unknown_status
NCT03045809
Women's Improvement of Sexual Health (WISH) Demonstration ProjectNo drug interventionsNot AvailableNot Availablecompleted
NCT01258556
The Impact of Probiotic Bacteria on the Efficacy of Anti-retroviral Therapy and Recurrence of Bacterial VaginosisNo drug interventionstreatment2 / 3completed
NCT02185456
Validation of a Novel Diagnostic, Prognostic Assay for Bacterial Vaginosisdiagnostic0unknown_status
NCT00889356
Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasistreatment3unknown_status
NCT01577537
A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosistreatment3completed
NCT01347632
Study of How Bacterial Vaginosis and Its Treatment Affects Cervical and Vaginal TissuepreventionNot Availablecompleted
NCT02042352
PNA FISH, PCR and Gram Staining for Detection of Bacterial Vaginosis - a Comparative Clinical Study in a Danish IVF SettingNo drug interventionsNot AvailableNot Availablecompleted
NCT03303859
Bacterial Vaginosis Carriage in Early Pregnancy and Preterm Delivery in Martinique, F.W.INo drug interventionsNot AvailableNot Availablecompleted
NCT05652959
Real-world Performance and Safety of Cerviron® in the Treatment of VaginitisNo drug interventionsNot AvailableNot Availablecompleted
NCT06438575
Point of Care Diagnosis of Vaginal InfectionsNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT03839875
Evaluation of Efficacy and Safety of Gynomax® XL OvuleNo drug interventionstreatment4completed
NCT01762670
GoldenCareTM for the Treatment of Bacterial Vaginosistreatment1 / 2terminated
NCT02203942
Comparing NAAT Testing to Standard Methods for the Diagnosis of VaginitisNo drug interventionsNot AvailableNot Availablecompleted
NCT06123299
A Randomised, Partly-blinded Investigation to Evaluate the Clinical Performance and Safety of pHyph in Adult Women With Bacterial Vaginosis Compared With an Untreated Control GroupNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00324818
Treatment of Bacterial Vaginosistreatment4completed
NCT02527941
Effect of Bacterial Vaginosis on HIV Susceptibility and Female Genital Immunologybasic_science1completed
NCT00229216
Treatment of Bacterial Vaginosis With Oral Tinidazoletreatment3completed
NCT01160796
Lcr35® for Bacterial Vaginosis PreventionNo drug interventionsprevention3completed
NCT02348463
Treatment of Bacterial Vaginosis in Early Pregnancy in Skaraborg and the Effect on Spontaneous Preterm DeliveryNot AvailableNot Availablecompleted
NCT06154239
Screening With Tampons: Evaluating Diagnostic Accuracy and HPV and Assessing Participant ViewsNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT01245322
Treatment of Bacterial Vaginosis Combined With Human LactobacilliNo drug interventionstreatment4completed
NCT06349122
Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birthtreatment4not_yet_recruiting
NCT04640922
Clinical Performance and Safety of the Gedea Pessary in Adult Women With Bacterial VaginosisNo drug interventionstreatmentNot Availablecompleted
NCT05278130
Serial Screening and Treatment of Bacterial Vaginosis TrialNo drug interventionsdiagnosticNot Availablerecruiting
NCT01089348
A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosistreatment2 / 3unknown_status
NCT04370548
DARE-BV1 in the Treatment of Bacterial Vaginosis (DARE-BVFREE)No drug interventionstreatment3completed
NCT00536848
The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patientstreatment2 / 3unknown_status
NCT01471457
Trial of Trimosan Gel Effect on Pessary-associated Bacterial Vaginosisprevention2 / 3completed
NCT06516757
A Single Group Study to Evaluate the Effects of a Boric Acid Suppository on Vaginal Health.No drug interventionssupportive_careNot Availablecompleted
NCT04638257
Role of Oral Lactobacilli on Vaginal Flora of Pregnant WomenNo drug interventionstreatment1completed
NCT03187457
PreFem: "What Happens to the Vaginal Microbiota When a BV Infection is Treated With Metronidazole?"No drug interventionsscreeningNot Availablecompleted
NCT06472765
Vaginal Ecosystem and Network in the United States StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02459665
Rwanda Vaginal Microbiota Restoration StudypreventionNot Availablecompleted
NCT00303082
Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidityprevention3terminated
NCT00313131
Study of the Management of Vaginal Discharge in West African Using Single Dose Treatmentstreatment3completed
NCT01335373
Observational Program Neo-Penotran® ForteNot AvailableNot Availablecompleted
NCT02866227
TOL-463 Phase 2 Study for VaginitisNo drug interventionstreatment2completed
NCT03601429
Dietary Supplementation of Lactogyn in Women With Bacterial VaginosisNo drug interventionspreventionNot Availablecompleted
NCT02210689
A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Womentreatment3completed
NCT03116789
Analysis of Ameliorative Effects of Oral Probiotics on Bacterial VaginosisNo drug interventionssupportive_careNot Availablecompleted
NCT01829204
Prospective Data Bank Creation to Study Vaginal ConditionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00667368
Bacterial Vaginosis Home Screening to Prevent STDstreatment3completed
NCT00070746
Perinatal Infections in PakistanNo drug interventionsNot AvailableNot Availablecompleted
NCT02946346
Kinetics and Ecology of Human Papillomavirus Genital Infections in Young WomenNo drug interventionsbasic_scienceNot Availableterminated
NCT01125410
Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosistreatment3completed
NCT00545181
Recurrent Bacterial Vaginosis and Vaginal Acidifying Gel TrialtreatmentNot Availablecompleted
NCT01230814
Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Womenprevention2completed
NCT05354050
Pharmacokinetic Study of DARE-BV1No drug interventionstreatment1completed
NCT00217308
Effect of Probiotic Lactobacilli on Vaginal Flora of Pregnant Women at High Risk for Preterm DeliveryNo drug interventionstreatment1withdrawn
NCT03099408
Oral Metronidazole With Lactobacillus Vaginal Suppositories to Prevent Recurrence of Bacterial Vaginosistreatment4completed
NCT02744638
Effect of a Yoghurt Containing Four Probiotic Lactobacillus Strains on Bacterial Vaginosissupportive_careNot Availablecompleted
NCT01577238
A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosistreatment3completed
NCT06486103
A Clinical Study to Determine the Safety and Efficacy of an Oral Probiotic Supplementation to Improve Bacterial Vaginosis in FemalesNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02905890
The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosisprevention4completed
NCT05340790
First in Human Study in Healthy Volunteers of Antimicrobial Peptide PL-18 Vaginal SuppositoriesNo drug interventionstreatment1recruiting
NCT06469164
A First-in-human Safety Trial of BNT331 Administered as Single Ascending Doses in Healthy Women and as Multiple Ascending Doses in Women Diagnosed With Bacterial VaginosisNo drug interventionstreatment1recruiting
NCT00140764
Intravaginal Treatment of Disturbances of Vaginal Flora Among HIV Infected and Uninfected Women in MalawiNo drug interventionstreatment3completed
NCT05211921
Single Arm Study of Multi-Gyn ActiGel Plus for Treatment of Bacterial VaginosisNo drug interventionstreatmentNot Availablecompleted
NCT00682721
Valacyclovir Suppression to Improve the Stability of Vaginal Flora Among HSV-2 Seropositive WomenpreventionNot Availablewithdrawn
NCT02295579
Will Lactobacillus Increase Cure Rate After Treatment of Bacterial Vaginosis and Chronic Vulvovaginal CandidaNo drug interventionsNot AvailableNot Availablecompleted
NCT00556179
Lactoserum (Dermacyd Femina®) and Prevention of Recurrence of Bacterial VaginosisNo drug interventionsprevention4completed
NCT00318253
The Effects of Cranberry Juice on Bacterial AdhesionNo drug interventionspreventionNot Availablecompleted
NCT03091777
Study Evaluating the Equivalence of GDC-229 and Metronidazole Vaginal Gel 0.75% in the Treatment of Bacterial Vaginosistreatment3completed
NCT06056947
Evaluation of Efficacy and Safety of Two New Formulations Compared to Gynomax® XL OvuleNo drug interventionstreatment3completed
NCT05386147
Flourish HEC to Prevent Recurrence of BVNo drug interventionspreventionNot Availablecompleted
NCT03930745
Suppression Of Bacterial Vaginosis (BV) [SUBVert]No drug interventionstreatment2completed
NCT02186145
Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infectionstreatment3unknown_status
NCT04219605
Evaluation of a Rapid Microscopic Diagnostic System for Different Vaginitis ConditionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01152528
Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm DeliveryNo drug interventionsdiagnostic3unknown_status
NCT00752193
Safety and Efficacy of a Vaginally Administered Probiotic Lactobacilli Delivery System.No drug interventionssupportive_careNot Availablecompleted
NCT00124878
Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the CommunityNo drug interventionsprevention3unknown_status
NCT02236156
Efficacy and Safety Study of SPL7013 Gel to Prevent the Recurrence of Bacterial Vaginosis (BV)prevention3completed
NCT01421615
Effect of Different Courses of Lactobacilli Treatment on Bacterial Vaginosis and Pregnancy OutcomesNo drug interventionstreatment1unknown_status
NCT00799500
Bacterial Vaginosis in Pregnancy: Detection by Weekly Vaginal pH TestingNo drug interventionspreventionNot Availablecompleted
NCT00464542
Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Studytreatment4completed
NCT01621399
Safety and Efficacy Study to Treat Bacterial VaginosisNo drug interventionstreatment3completed
NCT02147899
A Phase 2 Study of SYM-1219 to Treat Bacterial Vaginosistreatment2completed
NCT06131749
Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South AfricaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02863536
A Study of the New Medical Device Polybactum®No drug interventionspreventionNot Availablecompleted
NCT05753813
Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiomebasic_science0recruiting
NCT03894813
Probiotics as Adjuvant Treatment for Bacterial Vaginosistreatment4completed
NCT01993524
Supplementation of Standard Antibiotic Therapy With Oral Probiotics for Bacterial VaginosisNo drug interventionssupportive_careNot Availablecompleted
NCT01020396
Bioequivalence of Metronidazole Gel, 0.75% in the Treatment of Bacterial Vaginosisother1 / 2completed
NCT00802386
Bacterial Vaginosis Screening at IUD InsertionNo drug interventionsNot AvailableNot Availablecompleted
NCT00635622
Safety and Efficacy Study of Lactobacillus Administered Vaginally in Women With Bacterial VaginosisNot Available2completed
NCT05701722
Effect of Flourish HEC Vaginal Care System on BV Recurrence and the Vaginal MicrobiomeNo drug interventionspreventionNot Availablecompleted
NCT01800825
Clindamycin to Reduce Preterm Birth in a Low Resource Settingprevention4completed
NCT01201057
Dose Ranging Study of SPL7013 Gel for Treatment of Bacterial Vaginosis (BV)treatment2completed
NCT02452866
Open-Label Study to Evaluate Safety of A Single Dose of SYM-1219treatment3completed
NCT03357666
Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosistreatment2unknown_status
NCT06263465
Precision Vaginal Microbiome Transplantation in Women With Bacterial VaginosisNo drug interventionsotherNot Availablerecruiting
NCT06135974
Vaginal lIve Biotherapeutic RANdomized Trialtreatment0recruiting
NCT00542074
Bacterial Vaginosis; A Randomized Trial to Reduce RecurrenceNo drug interventionspreventionNot Availablecompleted
NCT00537576
Safety Study of Lactobacillus Administered Vaginally to Healthy Womenother1completed
NCT05788991
Comparison of Dequalinium Chloride (Fluomizin) vs Oral Metronidazole for the Treatment of Bacterial Vaginosistreatment4terminated
NCT00720291
Inflammation and Treatment of Bacterial Vaginosis Near TermtreatmentNot Availablecompleted
NCT01450462
Vitamin D and Sexual HealthNo drug interventionstreatmentNot Availablecompleted
NCT00207480
Brief, Behavioral Intervention to Reduce Douching Among Adolescent and Young WomenNo drug interventionseducational_counseling_training1suspended
NCT05060029
A Pilot Study to Evaluate the Efficacy and Safety of Lactobacillus Species Suppositories on Vaginal Health and pHtreatment4unknown_status
NCT02445989
Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunityprevention4completed
NCT03080740
The Efficacy and Safety Study of Clindamycin Palmitate Hydrochloride Dispersible Tablet Treatment of Bacterial Vaginosistreatment4unknown_status
NCT05434104
The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Studyhealth_services_researchNot Availablenot_yet_recruiting
NCT02432404
Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunityprevention4completed
NCT02376972
Efficacy and Safety Study of Rifaximin Vaginal Tablets in Bacterial Vaginosistreatment2terminated
NCT05022212
Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisitionprevention2completed
NCT05590195
Effect of PreforPro® on Urinary and Vaginal HealthNo drug interventionstreatment3not_yet_recruiting
NCT00510614
Tinidazole for Recurrent Bacterial Vaginosis: A Pilot Studyprevention0completed
NCT00799214
BASIC (Boric Acid, Alternate Solution for Intravaginal Colonization) Studytreatment2 / 3completed
NCT02150655
Study of the Microbiota, Metabolome, and Environmental Toxins in Relation to Reproductive Health in Rwandan Womenbasic_science0completed
NCT02237950
Efficacy and Safety Study of SPL7013 Gel to Prevent the Recurrence of Bacterial Vaginosis (BV)prevention3completed
NCT03734523
Clinical Trial to Survey Results of Flourish Vaginal Care System for Recurrent Bacterial VaginosisNo drug interventionsNot AvailableNot Availablecompleted
NCT02766023
LACTIN-V Study for Recurrent Bacterial Vaginosisprevention2completed
NCT06458543
Optimization of Bacterial Vaginosis Treatment in Women of Reproductive Agetreatment4recruiting
NCT06450990
Efficacy, Safety, and Dose-response of a Live Biotherapeutic Product in Women With Acute Vaginal InfectionNo drug interventionstreatment1 / 2not_yet_recruiting
NCT05796921
Lacticaseibacillus Rhamnosus CA15 (DSM 33960) Strain as a New Driver in Restoring the Normal Vaginal MicrobiotaNo drug interventionstreatmentNot Availablerecruiting
NCT02173184
Safety and Efficacy Study of Gynevac Lactobacillus Vaccine in the Treatment of Bacterial VaginosisNo drug interventionstreatment3unknown_status