Respiratory Tract Infections (RTI)

Also known as: Respiratory Infections / Respiratory Infection / Infections, Respiratory Tract / Respiratory Tract Infection / Infections, Respiratory / Respiratory Tract Infections / Infection, Respiratory Tract / Respiratory tract infections NEC / Recurrent Upper and Lower Respiratory Tract Infections (RTIs) / Infection respiratory / Respiratory tract infection (disorder) / Respiratory tract infection NOS / RTI / Respiratory (infection NOS) or (other diseases of NEC) / Unspecified respiratory tract infection / Respiratory tract infection (& [acute lower] or [lower])

DrugDrug NameDrug Description
DB00415AmpicillinA penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
DB01139CefapirinA first generation cephalosporin indicated in the treatment of susceptible bacterial infections.
DB01333CefradineA first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues.
DB00567CephalexinA first generation cephalosporin used to treat certain susceptible bacterial infections.
DB00618DemeclocyclineA tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
DB09357DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
DB00254DoxycyclineA tetracycline antibiotic used to treat a wide variety of bacterial infections.
DB05057ErdosteineA mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD).
DB00199ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
DB01321JosamycinA macrolide antibiotic used for the treatment of various susceptible bacterial infections.
DB01017MinocyclineA tetracycline analog used to treat a wide variety of infections in the body.
DB08813NadroparinA low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction.
DB09320Procaine benzylpenicillinA local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection.
DB00778RoxithromycinAn antibiotic used to treat a variety of susceptible bacterial infections.
DB01001SalbutamolA beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
DrugDrug NameTargetType
DB00415AmpicillinSerum albumincarrier
DB00415AmpicillinSolute carrier family 22 member 5transporter
DB00415AmpicillinSolute carrier family 15 member 1transporter
DB00415AmpicillinSolute carrier family 15 member 2transporter
DB00415AmpicillinPenicillin-binding protein 2atarget
DB00415AmpicillinPenicillin-binding protein 1btarget
DB00415AmpicillinPenicillin-binding protein 3target
DB00415AmpicillinPenicillin-binding protein 1Atarget
DB00415AmpicillinPenicillin-binding protein 2Btarget
DB00415AmpicillinMonocarboxylate transporter 1transporter
DB00415AmpicillinSolute carrier family 15 member 1target
DB00415AmpicillinSolute carrier family 15 member 2target
DB00415AmpicillinAngiopoietin-1 receptortarget
DB01139CefapirinPenicillin-binding protein 1Atarget
DB01333CefradineSolute carrier family 22 member 5transporter
DB01333CefradineSolute carrier family 15 member 1transporter
DB01333CefradineSolute carrier family 15 member 2transporter
DB01333CefradineSolute carrier family 22 member 6transporter
DB01333CefradinePenicillin-binding protein 1Atarget
DB01333CefradineCytochrome P450 3A4enzyme
DB01333CefradineMultidrug and toxin extrusion protein 1transporter
DB00567CephalexinSerum albumincarrier
DB00567CephalexinSolute carrier family 22 member 5transporter
DB00567CephalexinSolute carrier family 15 member 1transporter
DB00567CephalexinSolute carrier family 15 member 2transporter
DB00567CephalexinSolute carrier family 22 member 6transporter
DB00567CephalexinSolute carrier family 22 member 8transporter
DB00567CephalexinMultidrug and toxin extrusion protein 1transporter
DB00567CephalexinPenicillin-binding protein 3target
DB00567CephalexinPenicillin-binding protein 2atarget
DB00567CephalexinPenicillin-binding protein 1btarget
DB00567CephalexinPenicillin-binding protein 1Atarget
DB00567CephalexinPenicillin-binding protein 2Btarget
DB00618Demeclocycline30S ribosomal proteintarget
DB00618DemeclocyclineVasopressin V2 receptortarget
DB00254Doxycycline16S ribosomal RNAtarget
DB00254DoxycyclineSolute carrier family 22 member 6transporter
DB00254DoxycyclineCytochrome P450 3A4enzyme
DB00254DoxycyclineATP-binding cassette sub-family B member 5transporter
DB05057ErdosteineAdenosine deaminaseenzyme
DB00199Erythromycin23S ribosomal RNAtarget
DB00199ErythromycinCytochrome P450 3A4enzyme
DB00199ErythromycinCytochrome P450 3A7enzyme
DB00199ErythromycinP-glycoprotein 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1B1transporter
DB00199ErythromycinMotilin receptortarget
DB00199ErythromycinPotassium voltage-gated channel subfamily H member 2target
DB00199ErythromycinCytochrome P450 3A5enzyme
DB00199ErythromycinSolute carrier organic anion transporter family member 1B3transporter
DB00199ErythromycinBile salt export pumptransporter
DB00199ErythromycinCanalicular multispecific organic anion transporter 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1A2transporter
DB01321Josamycin50S ribosomal protein L4target
DB01017Minocycline30S ribosomal protein S4target
DB01017Minocycline30S ribosomal protein S9target
DB01017Minocycline16S ribosomal RNAtarget
DB01017MinocyclineInterleukin-1 betatarget
DB01017MinocyclineArachidonate 5-lipoxygenasetarget
DB01017MinocyclineMatrix metalloproteinase-9target
DB01017MinocyclineVascular endothelial growth factor Atarget
DB01017MinocyclineCaspase-1target
DB01017MinocyclineCaspase-3target
DB01017MinocyclineCytochrome ctarget
DB01017MinocyclineSolute carrier family 22 member 6transporter
DB01017MinocyclineSolute carrier family 22 member 7transporter
DB01017MinocyclineOuter membrane protein Ftransporter
DB01017MinocyclineOuter membrane porin Ctransporter
DB01017MinocyclineMitogen-activated Protein Kinasestarget
DB01017MinocyclineNitric oxide synthase, inducibletarget
DB08813NadroparinProto-oncogene c-Fostarget
DB08813NadroparinMyc proto-oncogene proteintarget
DB08813NadroparinP-selectintarget
DB08813NadroparinAntithrombin-IIItarget
DB00778Roxithromycin50S ribosomal protein L10target
DB00778RoxithromycinP-glycoprotein 1target
DB00778RoxithromycinCytochrome P450 3A4enzyme
DB00778RoxithromycinCytochrome P450 2B6enzyme
DB01001SalbutamolBeta-2 adrenergic receptortarget
DB01001SalbutamolBeta-1 adrenergic receptortarget
DB01001SalbutamolCytochrome P450 3A4enzyme
DB01001SalbutamolBeta-3 adrenergic receptortarget
DrugDrug NamePhaseStatusCount
DB00798Gentamicin0Completed1
DB00512Vancomycin0Completed1
DB00316Acetaminophen1Completed1
DB06151Acetylcysteine1Completed1
DB00062Albumin human1Completed1
DB01060Amoxicillin1Completed2
DB00567Cephalexin1Completed3
DB00878Chlorhexidine1Completed1
DB00766Clavulanic acid1Completed2
DB11922Danirixin1Completed1
DB00514Dextromethorphan1Completed1
DB12134Gepotidacin1Completed5
DB14242Honey1Completed1
DB00218Moxifloxacin1Completed1
DB00388Phenylephrine1Completed1
DB00852Pseudoephedrine1Completed1
DB00207Azithromycin1 / 2Terminated1
DB16402BNT-162A11 / 2Recruiting1
DB15695BNT162b1 SARS-CoV-2 Vaccine1 / 2Recruiting1
DB15722CYNK-0011 / 2Active Not Recruiting1
DB15696Pfizer-BioNTech COVID-19 Vaccine1 / 2Recruiting1
DB16401Pidacmeran1 / 2Recruiting1
DB00362Anidulafungin2Terminated1
DB00207Azithromycin2Terminated1
DB01222Budesonide2Terminated1
DB01329Cefoperazone2Suspended1
DB00169Cholecalciferol2Completed1
DB00169Cholecalciferol2Recruiting1
DB11651Dactolisib2Unknown Status1
DB01234Dexamethasone2Recruiting1
DB01590Everolimus2Unknown Status1
DB00983Formoterol2Terminated1
DB00798Gentamicin2Completed1
DB14698Influenza A virus A/Brisbane/59/2007(H1N1) hemagglutinin antigen (UV,formaldehyde inactivated)2Completed2
DB10791Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated)2Completed1
DB14699Influenza A virus A/Uruguay/716/2007(H3N2) hemagglutinin antigen (UV,formaldehyde inactivated)2Completed2
DB14445Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (formaldehyde inactivated)2Completed1
DB10794Influenza B virus B/Brisbane/60/2008 antigen (formaldehyde inactivated)2Completed1
DB14439Influenza B virus B/Brisbane/60/2008 hemagglutinin antigen (UV, formaldehyde inactivated)2Completed2
DB00471Montelukast2Terminated1
DB00435Nitric Oxide2Terminated1
DB09152Nitrogen2Terminated1
DB11062Octisalate2Completed1
DB09535Octocrylene2Completed1
DB00635Prednisone2Terminated1
DB09324Sulbactam2Suspended1
DB06273Tocilizumab2Recruiting1
DB00512Vancomycin2Completed1
DB11094Vitamin D2Completed1
DB09321Zinc oxide2Completed1
DB14239Echinacea purpurea2 / 3Completed1
DB00316Acetaminophen3Withdrawn2
DB00613Amodiaquine3Completed1
DB01060Amoxicillin3Completed1
DB01060Amoxicillin3Recruiting1
DB00126Ascorbic acid3Withdrawn2
DB00207Azithromycin3Completed2
DB00207Azithromycin3Not Yet Recruiting1
DB12768BCG vaccine3Active Not Recruiting1
DB00112Bevacizumab3Not Yet Recruiting1
DB01413Cefepime3Unknown Status1
DB00169Cholecalciferol3Completed1
DB00766Clavulanic acid3Recruiting1
DB11651Dactolisib3Completed1
DB09213Dexibuprofen3Completed1
DB01611Hydroxychloroquine3Not Yet Recruiting1
DB01050Ibuprofen3Completed1
DB13156Inosine pranobex3Not Yet Recruiting1
DB00848Levamisole3Not Yet Recruiting1
DB01620Pheniramine3Withdrawn1
DB00388Phenylephrine3Withdrawn2
DB00205Pyrimethamine3Completed1
DB15672Rilematovir3Recruiting1
DB09036Siltuximab3Terminated1
DB01299Sulfadoxine3Completed1
DB09536Titanium dioxide3Withdrawn2
DB15801VPM10023Active Not Recruiting2
DB11094Vitamin D3Completed1
DB09321Zinc oxide3Withdrawn2
DB00316Acetaminophen4Completed1
DB00945Acetylsalicylic acid4Completed1
DB00207Azithromycin4Completed1
DB00207Azithromycin4Terminated1
DB12768BCG vaccine4Recruiting1
DB11897Beclomethasone dipropionate4Completed1
DB01212Ceftriaxone4Completed1
DB00537Ciprofloxacin4Recruiting1
DB00633Dexmedetomidine4Suspended1
DB14240Echinacea4Completed1
DB01221Ketamine4Suspended1
DB16541Lactobacillus casei4Completed1
DB04465Lactose4Completed1
DB16533OM854Unknown Status1
DB00198Oseltamivir4Completed1
DB00319Piperacillin4Completed1
DB00319Piperacillin4Recruiting1
DB00818Propofol4Suspended1
DB00728Rocuronium4Suspended1
DB09324Sulbactam4Completed2
DB01606Tazobactam4Recruiting1
DB00976Telithromycin4Completed1
DB00976Telithromycin4Terminated1
DB00207AzithromycinNot AvailableCompleted1
DB00207AzithromycinNot AvailableNot Yet Recruiting1
DB00493CefotaximeNot AvailableRecruiting1
DB01212CeftriaxoneNot AvailableRecruiting2
DB01211ClarithromycinNot AvailableCompleted3
DB14446Influenza A virus A/South Dakota/6/2007 (H1N1) live (attenuated) antigenNot AvailableCompleted1
DB14447Influenza A virus A/Uruguay/716/2007(H3N2) live (attenuated) antigenNot AvailableCompleted1
DB11037Influenza B virus B/Brisbane/60/2008 live (attenuated) antigenNot AvailableCompleted1
DB00760MeropenemNot AvailableRecruiting1
DB00646NystatinNot AvailableRecruiting1
DB00781Polymyxin BNot AvailableRecruiting1
DB12343TemocillinNot AvailableRecruiting1
DB00512VancomycinNot AvailableRecruiting1
DB00162Vitamin ANot AvailableCompleted2
DB01593ZincNot AvailableCompleted2