Osteogenesis Imperfecta (OI)

Also known as: Brittle Bone Disease / Osteogenesis Imperfecta / Osteogenesis imperfecta (disorder)

Drug	Drug Name	Drug Description
DB00630	Alendronic acid	A bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis.
DB11620	Neridronic Acid	A bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis.

Drug	Drug Name	Target	Type
DB00630	Alendronic acid	Farnesyl pyrophosphate synthase	target
DB00630	Alendronic acid	Tyrosine-protein phosphatase non-receptor type 4	target
DB00630	Alendronic acid	Receptor-type tyrosine-protein phosphatase S	target
DB00630	Alendronic acid	Receptor-type tyrosine-protein phosphatase epsilon	target
DB00630	Alendronic acid	V-type proton ATPase catalytic subunit A	target
DB00630	Alendronic acid	Hydroxylapatite	target
DB11620	Neridronic Acid	Farnesyl pyrophosphate synthase	target

Drug	Drug Name	Phase	Status	Count
DB00282	Pamidronic acid	Not Available	Completed	1
DB00302	Tranexamic acid	Not Available	Completed	1
DB17840	AGA2115	1	Recruiting	1
DB01008	Busulfan	1	Completed	1
DB00531	Cyclophosphamide	1	Completed	1
DB00091	Cyclosporine	1	Completed	1
DB12396	Fresolimumab	1	Completed	1
DB11866	Romosozumab	1	Completed	1
DB15726	Human Umbilical Cord Mesenchymal Stem Cells	1 / 2	Not Yet Recruiting	1
DB06643	Denosumab	2	Completed	1
DB00884	Risedronic acid	2	Completed	1
DB14778	Setrusumab	2	Completed	1
DB14778	Setrusumab	2	Terminated	1
DB14778	Setrusumab	2	Withdrawn	1
DB06285	Teriparatide	2	Terminated	1
DB00399	Zoledronic acid	2	Completed	2
DB00399	Zoledronic acid	2	Terminated	1
DB14778	Setrusumab	2 / 3	Active Not Recruiting	1
DB06643	Denosumab	3	Terminated	2
DB00282	Pamidronic acid	3	Completed	1
DB00884	Risedronic acid	3	Completed	1
DB11866	Romosozumab	3	Recruiting	1
DB14778	Setrusumab	3	Active Not Recruiting	1
DB00052	Somatotropin	3	Completed	1
DB00399	Zoledronic acid	3	Completed	1
DB00630	Alendronic acid	4	Completed	2
DB00282	Pamidronic acid	4	Completed	1
DB00884	Risedronic acid	4	Recruiting	1
DB06285	Teriparatide	4	Completed	1
DB06285	Teriparatide	4	Unknown Status	1
DB00399	Zoledronic acid	4	Unknown Status	1