Stress-induced-phosphoprotein 1

Details

Name
Stress-induced-phosphoprotein 1
Synonyms
  • Hop
  • Hsc70/Hsp90-organizing protein
  • Renal carcinoma antigen NY-REN-11
  • STI1
  • Transformation-sensitive protein IEF SSP 3521
Gene Name
STIP1
Organism
Humans
Amino acid sequence
>lcl|BSEQ0049656|Stress-induced-phosphoprotein 1
MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYED
GCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLA
ERKFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLS
VLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKD
FDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIA
KAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLA
LEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEEC
IQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHD
SPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLI
AIR
Number of residues
543
Molecular Weight
62638.7
Theoretical pI
Not Available
GO Classification
Functions
chaperone binding / Hsp70 protein binding / protein C-terminus binding / RNA binding
Processes
response to stress
Components
Golgi apparatus / myelin sheath / nucleus / protein complex
General Function
Acts as a co-chaperone for HSP90AA1 (PubMed:27353360). Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90 (By similarity).
Specific Function
Chaperone binding
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
Gene sequence
>lcl|BSEQ0049657|Stress-induced-phosphoprotein 1 (STIP1)
ATGGAGCAGGTCAATGAGCTGAAGGAGAAAGGCAACAAGGCCCTGAGCGTGGGTAACATC
GATGATGCCTTACAGTGCTACTCCGAAGCTATTAAGCTGGATCCCCACAACCACGTGCTG
TACAGCAACCGTTCTGCTGCCTATGCCAAGAAAGGAGACTACCAGAAGGCTTATGAGGAT
GGCTGCAAGACTGTCGACCTAAAGCCTGACTGGGGCAAGGGCTATTCACGAAAAGCAGCA
GCTCTAGAGTTCTTAAACCGCTTTGAAGAAGCCAAGCGAACCTATGAGGAGGGCTTAAAA
CACGAGGCAAATAACCCTCAACTGAAAGAGGGTTTACAGAATATGGAGGCCAGGTTGGCA
GAGAGAAAATTCATGAACCCTTTCAACATGCCTAATCTGTATCAGAAGTTGGAGAGTGAT
CCCAGGACAAGGACACTACTCAGTGATCCTACCTACCGGGAGCTGATAGAGCAGCTACGA
AACAAGCCTTCTGACCTGGGCACGAAACTACAAGATCCCCGGATCATGACCACTCTCAGC
GTCCTCCTTGGGGTCGATCTGGGCAGTATGGATGAGGAGGAAGAGATTGCAACACCTCCA
CCACCACCCCCTCCCAAAAAGGAGACCAAGCCAGAGCCAATGGAAGAAGATCTTCCAGAG
AATAAGAAGCAGGCACTGAAAGAAAAAGAGCTGGGGAACGATGCCTACAAGAAGAAAGAC
TTTGACACAGCCTTGAAGCATTACGACAAAGCCAAGGAGCTGGACCCCACTAACATGACT
TACATTACCAATCAAGCAGCGGTATACTTTGAAAAGGGCGACTACAATAAGTGCCGGGAG
CTTTGTGAGAAGGCCATTGAAGTGGGGAGAGAAAACCGAGAAGACTATCGACAGATTGCC
AAAGCATATGCTCGAATTGGCAACTCCTACTTCAAAGAAGAAAAGTACAAGGATGCCATC
CATTTCTATAACAAGTCTCTGGCAGAGCACCGAACCCCAGATGTGCTCAAGAAATGCCAG
CAGGCAGAGAAAATCCTGAAGGAGCAAGAGCGGCTGGCCTACATAAACCCCGACCTGGCT
TTGGAGGAGAAGAACAAAGGCAACGAGTGTTTTCAGAAAGGGGACTATCCCCAGGCCATG
AAGCATTATACAGAAGCCATCAAAAGGAACCCGAAAGATGCCAAATTATACAGCAATCGA
GCTGCCTGCTACACCAAACTCCTGGAGTTCCAGCTGGCACTCAAGGACTGTGAGGAATGT
ATCCAGCTGGAGCCGACCTTCATCAAGGGTTATACACGGAAAGCCGCTGCGCTGGAAGCG
ATGAAGGACTACACCAAAGCCATGGATGTGTACCAGAAGGCGCTAGACCTGGACTCCAGC
TGTAAGGAGGCGGCAGACGGCTACCAGCGCTGTATGATGGCGCAGTACAACCGGCACGAC
AGCCCCGAAGATGTGAAGCGACGAGCCATGGCCGACCCTGAGGTGCAGCAGATCATGAGT
GACCCAGCCATGCGCCTTATCCTGGAACAGATGCAGAAGGACCCCCAGGCACTCAGCGAA
CACTTAAAGAATCCTGTAATAGCACAGAAGATCCAGAAGCTGATGGATGTGGGTCTGATT
GCAATTCGGTGA
Chromosome Location
11
Locus
11q13.1
External Identifiers
ResourceLink
UniProtKB IDP31948
UniProtKB Entry NameSTIP1_HUMAN
HGNC IDHGNC:11387
General References
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Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB09130Copperapproved, investigationalunknownDetails