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Ritodrine B2-Adrenergic Myometrial Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126043Drug actionRitodrine is a adrenergic beta agonist used for the treatment and prophylaxis of premature labour. Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adren...
Drugs: ATP · Ritodrine · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphateClenbuterol Action Pathway
smpdb.ca/view/SMP0126097Drug actionClenbuterol is a beta-2 adrenergic agonist used as a bronchodilator. This drug is taken orally and is used for the treatment of asthma, bronchitis, and COPD. It exerts its effect through activation of adenylyl cyclase leading to muscle r...
Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Clenbuterol · Cyclic adenosine monophosphateChlordiazepoxide Action Pathway
smpdb.ca/view/SMP0126120Drug actionChlordiazepoxide is a benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Chlordiazepoxide · Calcium · Magnesium cation +3 moreLabetalol B1-Adrenergic Cardiac Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126203Drug actionLabetalol is a non-selective beta blocker and is a racemic mixture of 2 diastereoisomers . It can be administered orally, where it passes through hepatic portal circulation, and enters the bloodstream and travels to act on cardiomyocytes...
Nalmefene Opioid Antagonist Action Pathway
smpdb.ca/view/SMP0126315Drug actionIn vivo, studies have demonstrated that nalmefene reduces alcohol consumption, possibly by modulating cortico-mesolimbic functions. … Preclinical studies suggest that nalmefene restores alcohol-induced dysregulations of the MOR/endorphins and the KOR/dynorphin system.
Drugs: ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid · Pyrophosphoric acid +1 moreSalbutamol Action Pathway
smpdb.ca/view/SMP0126574Drug actionSalbutamol is a beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms. It can be found under the brand names Airomir, Combivent, Proair, Proventil, Ventolin, and Xope...
Drugs: ATP · Albuterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphateDronedarone Multiple Ion Channel Cardiac Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126677Drug actionDronedarone is an antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. It is administered as an oral tablet and can be found under the brand name Multaq. Drone...
Famotidine H2 Anti-Histamine Action Pathway
smpdb.ca/view/SMP0126789Drug actionFamotidine is a histamine H2 receptor antagonist used to treat gastroesophageal reflux disease and various ulcers. Famotidine displays high selectivity towards H2 histamine receptors compared to other H2 anti-histamines. After being take...
Drugs: ATP · Famotidine · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphatePropylene glycol Drug Metabolism
smpdb.ca/view/SMP0130507MetabolicPropylene glycol is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Propylene glycol passes through the liver and is then excreted from the body mainly through the kidney.
Drugs: Propylene glycolAluminum zirconium octachlorohydrex gly Drug Metabolism
smpdb.ca/view/SMP0130523MetabolicAluminum zirconium octachlorohydrex gly is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Aluminum zirconium octachlorohydrex gly passes through the liver and is then excre...