Search

Displaying results 1061 - 1070 of 10000 in total
  1. Target

    Cytoplasmic tyrosine-protein kinase BMX

    go.drugbank.com/bio_entities/BE0009416
    TargetHumans

    May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells … Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis.

    Synonyms: Bone marrow tyrosine kinase gene in chromosome X protein
  2. Drug

    Alanine

    go.drugbank.com/drugs/DB00160
    ApprovedInvestigationalNutraceutical

    Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. … It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.

    Mixtures: Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec, AA-VenSynonyms: L-Alanin, L-alanine
  3. Drug

    Cobimetinib

    go.drugbank.com/drugs/DB05239
    ApprovedInvestigational

    It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or metastatic BRAF V600 mutation-positive melanoma. … Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction

    Categories: UGT2B7 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  4. Drug

    Hypochlorous acid

    go.drugbank.com/drugs/DB14135
    Investigational

    An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Chlor(I)-säure
  5. Indication

    Anorexia

    go.drugbank.com/conditions/DBCOND0004522
    Drugs: Dronabinol · Hemicellulase · Itopride · Megestrol acetate
    Synonyms: Decrease in appetite (finding)
  6. Indication

    Hyperglycemia

    go.drugbank.com/conditions/DBCOND0020377
    Drugs: Glycyrrhizic acid · Mifepristone
    Synonyms: High Level of Sugar (Glucose) in the Blood
  7. Indication

    Moderate Glabellar Frown Lines (GL)

    go.drugbank.com/conditions/DBCOND0146864
    Drugs: Botulinum toxin type A · DaxibotulinumtoxinA
    Synonyms: Moderate Glabellar Frown Lines (GL)
  8. Drug

    Leucine

    go.drugbank.com/drugs/DB00149
    ApprovedInvestigationalNutraceutical

    An essential branched-chain amino acid important for hemoglobin formation.

    Salts: L-Leucine hydrochlorideMixtures: Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec, Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
  9. Drug

    Valine

    go.drugbank.com/drugs/DB00161
    ApprovedInvestigationalNutraceutical

    Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.

    Mixtures: Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec, AA-VenSynonyms: L-valin, L-valine
  10. Indication

    Pancreatic Metastatic Cancer

    go.drugbank.com/conditions/DBCOND0070216
    Drugs: Erlotinib · Leucovorin
    Synonyms: Secondary malignant deposit in pancreas