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Methamphetamine Norepinephrine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126618Drug actionThese cascades help regulate memory and attention. … This causes increased heartrate, increased blood pressure caused by vasoconstriction, increased breathing rate, and decreased appetite and digestion.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Norepinephrine · Dopamine · Levodopa +4 moreAmine Oxidase Norepinephrine
smpdb.ca/view/SMP0130460Physiological) as well as toxins and carcinogens in foods and the environment. … The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine.
Tyrosine Metabolism
smpdb.ca/view/SMP0000006MetabolicThyroid hormones are produced and released by the thyroid gland and include triiodothyronine (T3) and thyroxine (T4). These two hormones are responsible for regulating metabolism. … Catecholamines such as L-DOPA, dopamine and methoxytyramine are produced mainly by the chromaffin cells of the adrenal medulla and by neuronal cells found in the brain.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 moreTyrosinemia, Transient, of the Newborn
smpdb.ca/view/SMP0000494Diseaseand derivatives. … The inhibition is reversible by removal of excess substrate and by reducing agents such as ascorbic acid, 2, 6-dichiorophenolindophenol, and a number of hydroquinone and phenylenediamine compounds.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 moreDopamine beta-Hydroxylase Deficiency
smpdb.ca/view/SMP0000498DiseaseNoradrenaline and adrenaline are generally not detectable in plasma, urine, and cerebrospinal fluid, but dopamine is increased 7- to 12-fold in plasma, 4-fold in urine, and 20-fold in CSF. … Treatment with dihydroxyphenylserine has been shown to reduce symptoms and signs of postural hypotension and increase plasma levels of noradrenaline.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 moreSalicylic Acid Action Pathway
smpdb.ca/view/SMP0000709Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. … Salicylic acid can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Salicylic acid · Calcium · Magnesium cation +5 moreDopamine Action Pathway
smpdb.ca/view/SMP0125137Drug actionLow doses of dopamine cause vasodilation while can help with renal failure and related conditions. … Dopamine is a neurotransmitter that can be taken as a tablet for hemodynamic imbalances caused by many heart problems and diseases.
Amitriptyline Norepinephrine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0125187Drug actionThe norepinephrine is released into the synapse and acts on α1, β1 and β2receptors which contribute to mood improvements. … Amitriptyline by blocking the reuptake of both serotonin and norepinephrine neurotransmitters. In adrenergic neurons, norepinephrine is synthesized from tyrosine and stored in synaptic vesicles.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Amitriptyline · Sapropterin · Norepinephrine +5 moreMethamphetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0125231Drug actionMethamphetamine (metamfetamine) is a psychostimulant and sympathomimetic drug. It is mainly taken recreationally but can be taken for ADHD and exogenous obesity in the form of a drug called Desoxyn. … Methamphetamine induces effects of euphoria and affects heart rate, body temperature, blood pressure, appetite, attention, mood, and responses associated with alertness or alarm conditions.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin +9 moreBupropion Action Pathway
smpdb.ca/view/SMP0125268Drug actionThis helps regulate mood and behaviour in the brain as well as activating the reward system. Norepinephrine's effects on MDD is less studied and less understood than dopamine. … Norepinephrine activates Alpha-1A adrenergic receptors in the brain, which are desensitized in the brains of depressed patients and implicated in the limbic system for regulating behaviour and mood.