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Displaying results 1211 - 1220 of 10000 in total
  1. Drug

    Homosalate

    go.drugbank.com/drugs/DB11064
    Approved

    Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. … Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light.

    Mixtures: Miami Beach SPF 50 Kids C/S Sunscreen, Miami Beach SPF 50 Kids C/S SunscreenCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Calcium carbimide

    go.drugbank.com/drugs/DB09116
    ApprovedWithdrawn

    Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. … The current status of calcium carbimide is cancelled post marketing.[L1113]

    Synonyms: Cyanamide, calcium salt (1:1), methanediimine, calcium salt (1:1)
  3. Drug

    Indigotindisulfonic acid

    go.drugbank.com/drugs/DB11577
    ApprovedInvestigational

    [A251405] Indigotindisulfonic acid is used in clinical medicine to determine patency of the urinary collecting system, and to assist in specific surgical procedures such as cystourethroscopy. … This compound is an acid-base indicator and is used in the production of food colorants and pH tests.

    Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingSynonyms: 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid, FD&C Blue #2
  4. Drug

    Human thrombin

    go.drugbank.com/drugs/DB11571
    ApprovedInvestigational

    This transformation mimics the final coagulation cascade step which involves the clotting mass that adheres to the wound surface and achieves hemostasis and sealing of open tissues. … Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting.

    Mixtures: EVICEL® SELLANTE DE FIBRINA HUMANA
  5. Drug

    Clofarabine

    go.drugbank.com/drugs/DB00631
    ApprovedInvestigational

    Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.

    Categories: Heterocyclic Compounds, 2-Ring, OCT2 Substrates with a Narrow Therapeutic IndexSynonyms: (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
  6. Pathway

    Muscular Gs Protein Cascade

    smpdb.ca/view/SMP0126976
    Physiological

    G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior. Their...

    Drugs: ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  7. Drug

    Selenious acid

    go.drugbank.com/drugs/DB11127
    Approved

    Selenium (Se) has been demonstrated to prevent cancer in numerous animal models when administered selenium at levels exceeding the nutritional requirements. … Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation.

    Mixtures: Micro+ Te Pediatric, Vitamins C Plus E W.beta Carotene and SeProducts: Micro Se, Formula-SE
  8. Drug

    Tagraxofusp

    go.drugbank.com/drugs/DB14731
    ApprovedInvestigational

    [A253762] It was also approved by the European Commission on January 7, 2021.[L43712] … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in _Escherichia coli_.

    Synonyms: Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor
  9. Drug

    Calcium ascorbate

    go.drugbank.com/drugs/DB14483
    ApprovedNutraceutical

    Mixtures: KORDEL`S C TIME ACID FREE C 1000MG TABLET, Se-Vate 21/7Categories: Vitamin C and analogues, Compounds used in a research, industrial, or household setting
  10. Pathway

    Thioguanine Action Pathway

    smpdb.ca/view/SMP0122727
    Drug action

    Thioguanine is an antineoplastic compound used to treat acute leukemia. It is usually administered orally and delivered to the site of action through the blood. Thioguanine has similar properties to 6-mercaptopurine as they share similar...

    Drugs: Ademetionine · ATP · Tioguanine · Magnesium cation · 5-O-phosphono-alpha-D-ribofuranosyl diphosphate · Pyrophosphoric acid
    Enzymes: Thiopurine S-methyltransferase