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Metabolism and Physiological Effects of Para-cresol
smpdb.ca/view/SMP0123214MetabolicPara-cresol(P-cresol) is a phenolic compound that is formed through gut microbial metabolism from the amino acid tyrosine which is acquired from foods that are high in protein. … P-cresol is shown to be associated with cardiovascular disease and it can also inhibit endothelial cell proliferation.
Metabolism and Physiological Effects of Indoxyl Sulfate
smpdb.ca/view/SMP0123237MetabolicIt is also shown to cause vascular calcification and disrupt the electron transport chain and oxidative phosphorylation causing muscle atrophy … Indoxyl sulfate is an indole compound that is formed through gut microbial metabolism from dietary tryptophan and a sulfation reaction in liver hepatic cells.
Metabolism and Physiological Effects of N-Acetylserine
smpdb.ca/view/SMP0126556MetabolicN-Acetylserine can also be classified as an alpha amino acid or a derivatized alpha amino acid. … N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom.
Metabolism and Physiological Effects of N-Acetylthreonine
smpdb.ca/view/SMP0126703MetabolicThe human NatA complex co-translationally acetylates N-termini that bear a small amino acid (A, S, T, C, and occasionally V and G). … N-Acetylthreonine can also be classified as an alpha amino acid or a derivatized alpha amino acid.
Drugs: ThreonineMetabolism and Physiological Effects of N-Acetyltryptophan
smpdb.ca/view/SMP0126721MetabolicN-Acetyltryptophan can also be classified as an alpha amino acid or a derivatized alpha amino acid. … N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom.
Drugs: TryptophanMetabolism and Physiological Effects of Indolelacetyl glutamine
smpdb.ca/view/SMP0126755Metabolic, and indole lactic acid. … Several intestinal bacteria, such as Bacteroides, Clostridia, and E. coli, can catabolize Trp to tryptamine and indole pyruvic acid, which are then converted to indole-3-acetic acid, indole propionic acid
Metabolism and Physiological Effects of 3-Methylhistidine
smpdb.ca/view/SMP0126757Metabolicacid. … Methylamino acids are primarily proteogenic amino acids (found in proteins) which have been methylated (in situ) on their side chains by various methyltransferase enzymes.
Metabolism and Physiological Effects of O-Sulfotyrosine
smpdb.ca/view/SMP0126811MetabolicO-Sulfotyrosine belongs to the class of organic compounds known as phenylalanine and derivatives. … Secreted proteins and extracellular parts of membrane proteins that pass through the Golgi apparatus may be sulfated.
Metabolism and Physiological Effects of S-Adenosylhomocysteine
smpdb.ca/view/SMP0127690MetabolicIt is toxic to immature lymphocytes and can lead to immunosuppression. … Methionine can be obtained from foods such as meat, eggs, dairy products, and nuts and is converted to adenosylmethionine which is then further converted to adenosylhomocysteine in the hepatocytes of the
Enzymes: Large neutral amino acids transporter small subunit 1Congenital Bile Acid Synthesis Defect Type II
smpdb.ca/view/SMP0000314DiseaseChenodeoxycholic acid and cholic acid are decreased in plasma and urine. … Symptoms of this disease include cholestatic jaundice, atypical oxo and allo bile acids in urine and serum, liver failure, and steatosis.