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Isoflurophate Action Pathway (new)
smpdb.ca/view/SMP0126686Drug actionIsoflurophate is a cholinesterase inhibitor used to treat glaucoma, as it acts as a powerful miotic agent constricting the pupil and causing the aqueous fluid to flow out and relieve pressure. It acts by irreversibly binding to acetylcho...
Selegiline Action Pathway
smpdb.ca/view/SMP0126719Drug actionSelegiline is an irreversible monoamine oxidase inhibitor (MAOIs). It is indicated for the initial treatment of Parkinson's disease and for adjunct therapy in patients that are having decreased response to levodopa or carbadopa. This mol...
Nomifensine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0127002Drug actionNomifensine, formerly known as Merital capsules, is a dopamine reuptake inhibitor drug that was removed from the market in 1986 for increased incidence of hemolytic anemia. The drug was originally used to treat depression. Nomifensine st...
Amine Oxidase Norepinephrine
smpdb.ca/view/SMP0130460PhysiologicalThe monoamine oxidase is an enzyme that catalyzes the oxidative deamination of many amines like serotonin, norepinephrine, epinephrine, and dopamine. There are 2 isoforms of this protein: A and B. The first one is found in cells located ...
Cinnarizine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174985Drug actionCinnarizine is an anti-histaminic drug. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, al...
Carbinoxamine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174988Drug actionCarbinoxamine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Tripelennamine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174989Drug actionTripelennamine is a first-generation ethanolamine H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions s...
Methapyrilene H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175000Drug actionMethapyrilene is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Mepyramine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175002Drug actionMepyramine is an antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Acrivastine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175007Drug actionAcrivastine is an antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion. H1-antihistamines interfere with the agonist action of histami...