Search
Sertraline Mechanism of Action Action Pathway New
smpdb.ca/view/SMP0126512Drug actionSertraline binds selectively bind to the sodium dependent serotonin transporter and blocks the recycling of serotonin from the synapse.
Enzymes: Sodium-dependent serotonin transporterEscitalopram Mechanism of Action Action Pathway New
smpdb.ca/view/SMP0126509Drug actionIt's mechanism of action it to bind selectively bind to the sodium dependent serotonin transporter and blocking the recycling of serotonin from the synapse.
Enzymes: Sodium-dependent serotonin transporterFluvoxamine Mechanism of Action Action Pathway New
smpdb.ca/view/SMP0126511Drug actionIt's mechanism of action it to bind selectively bind to the sodium dependent serotonin transporter and blocking the recycling of serotonin from the synapse.
Enzymes: Sodium-dependent serotonin transporterMethysergide Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126851Drug actionMethysergide is an ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle. Methysergide is a semisynthetic ergot alkaloid ergometrine...
Enzymes: Sodium/calcium exchanger 1, Sodium-dependent serotonin transporterCabergoline Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126670Drug actionCabergoline stimulates centrally-located dopaminergic D2- and D3-receptors. Cabergoline is a long-acting agonist with a high affinity for D2 receptors. It also exhibits: weak agonist activity (in order of decreasing binding affinities) o...
Enzymes: Sodium-dependent dopamine transporterQuinagolide Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126673Drug actionNewer dopamine receptor agonists such as quinagolide and Cabergoline are shown to effectively inhibit prolactin secretion with improved efficacy over Bromocriptine. These drugs are effective in patients who are intolerant or resistant to...
Enzymes: Sodium-dependent dopamine transporterAmitriptyline Norepinephrine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0125187Drug actionAmitriptyline is a tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. The non-FDA-approved indications are anxiety, post-traumatic stre...
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Amitriptyline · Sapropterin · Norepinephrine +5 moreEnzymes: Sodium-dependent noradrenaline transporterFludarabine Action Pathway
smpdb.ca/view/SMP0126500Drug actionAfter entering the cell via the equilibration nucleoside transporter and the sodium/nucleoside cotransporter, the drug is phosphorylated to 2-fluoro-ara-A and then phosphorylated by the deoxycytidine kinase
Enzymes: Sodium/nucleoside cotransporter 2Chlorpromazine - Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126485Drug actionProchlorperazine and chlorpromazine are examples of this class of Phenothiazines. Phenothiazines antagonize the D2 receptor, most notably in the area postrema in the brain. IV, PO, and rectal (PR) formulations are available. Side effects...
Enzymes: Sodium-dependent dopamine transporterTriflupromazine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126491Drug actionTriflupromazine is a member of a class of drugs called phenothiazines, which are dopamine D1/D2 receptor antagonists. Triflupromazine is used particularly to control violent behavior during acute episodes of psychotic disorders. It can a...
Enzymes: Sodium-dependent dopamine transporter