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Metabolism and Physiological Effects of Oxalic acid
smpdb.ca/view/SMP0124875MetabolicThe oxalate formed in the liver form these 3 sources can enter the blood and have toxic effects in other tissues. Oxalate can promote cardiovascular disease, neurotoxicity and inflammation. … Glycine and hydroxyproline comes from protein sources in the diet such as red meat and eggs. Glycine Is converted into glyoxylate in the peroxisome by the enzyme d-amino acid oxidase.
Drugs: Pyridoxal phosphate · Ascorbic acid · Succinic acid · Glutamic acid · Glycine · Proline +4 moreEnzymes: D-amino-acid oxidase, Sodium- and chloride-dependent transporter XTRP3Metabolsim and Physiological Effects of Argininic acid
smpdb.ca/view/SMP0125504MetabolicThis accumulation causes arginine to instead be converted into α-keto-δ-guanidinovaleric acid by transamination. α-Keto-δ-guanidinovaleric acid is then hydrogenated to form argininic acid. … Arginnosuccinate is synthesized from citrulline and aspartic acid by the enzyme argininosuccinate synthase. That is catalyzed by argininosuccinate lyase to produce arginine and fumaric acid.
Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 moreEnzymes: D-amino-acid oxidase, Neutral amino acid transporter AMetabolism and Physiological Effects of Indolelactic Acid
smpdb.ca/view/SMP0126749MetabolicIndolelactic acid is present in various amounts, significantly higher in umbilical fetal plasma than in maternal plasma in the protein-bound form. … Indolelactic acid (CAS: 1821-52-9) is a tryptophan metabolite found in human plasma, serum, and urine.
Metabolism and Physiological Effects of Vanillic Acid
smpdb.ca/view/SMP0126881MetabolicVanillic acid, which is a chlorogenic acid, is an oxidized form of vanillin. It is also an intermediate in the production of vanillin from ferulic acid. … Vanillic acid is a phenolic acid found in some forms of vanilla and many other plant extracts. It is a flavouring and scent agent that produces a pleasant, creamy odour.
Metabolism and Physiological Effects of β-Hydroxybutyric acid
smpdb.ca/view/SMP0126987MetabolicThis acid is metabolized by 3-hydroxybutyrate dehydrogenase (catalyzes the oxidation of 3-hydroxybutyrate to form acetoacetate, using NAD+ as an electron acceptor). … Ketone synthesis in the liver produces acetoacetate and beta-hydroxybutyrate from two acetyl CoA molecules. Acetyl-CoA is a metabolite derived from glucose, fatty acid, and amino acid catabolism.
Enzymes: Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialMetabolism and Physiological Effects of 2-Aminobenzoic acid
smpdb.ca/view/SMP0126869DiseaseHas a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. … Kynureninase catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) (which is also known as 2-Aminobenzoic acid) and 3-hydroxyanthranilic acid (3
Enzymes: Neutral and basic amino acid transport protein rBAT, Neutral amino acid transporter AMetabolism and Physiological Effects of 4-Hydroxyphenylacetic acid
smpdb.ca/view/SMP0126879Metabolicp-Hydroxyphenylacetic acid can be found in numerous foods such as olives, cocoa beans, oats, and mushrooms. p-Hydroxyphenylacetic acid can be found throughout all human tissues and in all biofluids. … at the 2-position. p-Hydroxyphenylacetic acid is considered to be slightly soluble (in water) and acidic.
Metabolism and Physiological Effects of Indole Acetic Acid
smpdb.ca/view/SMP0123235MetabolicAfter being transported into gut microbes, tryptophan undergoes a reaction with the enzymes tryptophan monooxygenase and indole-3-acetamide hydrolase to form indole acetic acid. … Indole acetic acid is shown to cause inflammation and disrupt the electron transport chain and oxidative phosphorylation causing muscle atrophy.
Drugs: TryptophanEnzymes: Excitatory amino acid transporter 3Metabolism and Physiological Effects of 4-Hydroxyhippuric Acid
smpdb.ca/view/SMP0125537Metabolic4-Hydroxyhippuric, also known as 4-hydroxybenzoylglycine or 4-hydroxyhippate acid, is a metabolite of hippuric acid, and a uremic toxin. … Benzoic acid is present in many fruits, such as apricots, prunes, and berries; many vegetables such as mushrooms (fungus), snap peas, cucumbers, and radishes; spices such as cinnamon, cloves, and allspice
Indocyanine green acid form Drug Metabolism
smpdb.ca/view/SMP0130870MetabolicIndocyanine green acid form passes through the liver and is then excreted from the body mainly through the kidney. … Indocyanine green acid form is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Indocyanine green acid form