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Fludarabine Action Pathway
smpdb.ca/view/SMP0126500Drug actionFludarabine, also known as Fludara, is a purine analog (antimetabolite) used as a chemotherapeutic drug. This molecule is used in the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or...
Domperidone Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126605Drug actionDomperidone is known as a prokinetic dopamine antagonist. It acts as a gastrointestinal emptying (delayed) adjunct and peristaltic stimulant. The gastroprokinetic properties of domperidone are related to its peripheral dopamine receptor ...
Dihydroergocryptine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126659Drug actionAlpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino ...
Isocarboxazid Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126692Drug actionIsocarboxazid, also known as Marplan, is an antidepressant from the monoamine oxidase inhibitors (MAOIs) drug class. This drug is indicated in different disorders like major depression, dysthymic disorder, atypical disorder, panic disord...
Safinamide Action Pathway
smpdb.ca/view/SMP0126696Drug actionSafinamide is a monoamide oxidase inhibitor. It is indicated as an odd treatment of levodopa for Parkinson's disease. The monoamine oxidase is an enzyme that catalyzes the oxidative deamination of many amines like serotonin, norepinephri...
Doxylamine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0126731Drug actionDoxylamine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfe...
Mazindol Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126988Drug actionMazindol, commonly known as Sanorex, is a sympathomimetic used to treat Duchenne muscular dystrophy. It has similar side effects to amphetamine but is less toxic. This drug can be used as a short-term treatment of obesity when combined w...
Lisdexamfetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126990Drug actionLisdexamfetamine, known commonly as Vyvanse, is a prodrug of amphetamine paired with lysine and used mainly for treating ADHD and binge eating disorders. The drug was engineered to be abuse-resistant with a delayed release. ADHD is cause...
Dextroamphetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126994Drug actionDextroamphetamine, known commonly as Adderall, is a drug related to amphetamine and is used mainly for treating ADHD and narcolepsy. The drug was approved by the FDA in 2001 for treating ADHD, but the exact mechanisms for its effects are...
Serdexmethylphenidate Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0127003Drug actionSerdexmethylphenidate, known commonly combined with dexmethylphenidate as Azstarys, is a prodrug of dexmethylphenidate (CNS stimulant) used for first-line treatment of ADHD. ADHD is caused by an abnormality in the dopamine transporter ge...