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Displaying results 191 - 200 of 1485 in total
  1. Target

    Endonuclease III-like protein 1

    go.drugbank.com/bio_entities/BE0013972
    EnzymeTargetHumans

    The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. … The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.

    Synonyms: Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase
  2. Indication

    Classical Hodgkin's Lymphoma

    go.drugbank.com/conditions/DBCOND0113588
    Drugs: Brentuximab vedotin · Nivolumab
    Synonyms: Hodgkin's disease NOS, unspecified site (disorder), Hodgkin's granuloma of unspecified site (disorder)
  3. Indication

    Mycoplasma pneumoniae infection

    go.drugbank.com/conditions/DBCOND0117151
    Drugs: Azithromycin · Doxycycline · Erythromycin
    Synonyms: Mycoplasma infection, unspecified site
  4. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972....

    Products: ADALAT CAPSULAS POR 10 MG
  5. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestiv...

    Products: FUROSEMIDA TABLETAS POR 40 MG
  6. Drug

    Netilmicin

    go.drugbank.com/drugs/DB00955
    Approved

    Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRNA binding and the acceptor tRNA site.

  7. Drug

    Tranexamic acid

    go.drugbank.com/drugs/DB00302
    ApprovedInvestigational

    Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. ...

  8. Indication

    Arthritis, Unspecified

    go.drugbank.com/conditions/DBCOND0130530
    Drugs: (+)-menthol · (S)-camphor · 2-(l-menthoxy)ethanol · Acetaminophen · Acetylsalicylic acid · Borneol +22 more
    Synonyms: Unspecified osteoarthritis, unspecified site
  9. Drug

    Cyclosporine

    go.drugbank.com/drugs/DB00091
    ApprovedInvestigationalVet approved

    Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially...

    Products: BIOSPORIN ® CAPSULAS POR 50 MG
  10. Drug

    Acyclovir

    go.drugbank.com/drugs/DB00787
    ApprovedInvestigational

    Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. Acyclovir is generally used first line in the treatment of these viruses and so...

    Products: ACYCLOVIR TABLETAS POR 200 MG, ACICLOVIR POLVO PARA SUSPENSION POR 100 MG/5 ML