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Displaying results 21 - 30 of 226 in total
  1. Target

    Gamma-aminobutyric acid receptor subunit alpha-2

    go.drugbank.com/bio_entities/BE0000381
    TargetHumans

    Alpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:29961870, PubMed:31032849 … The alpha-2 subunit exhibits synaptogenic activity together with beta-2 and very little to no activity together with beta-3, the gamma-2 subunit being necessary but not sufficient to induce rapid synaptic

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-2
  2. Target

    Gamma-aminobutyric acid receptor subunit alpha-3

    go.drugbank.com/bio_entities/BE0000523
    TargetHumans

    Alpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:16412217, PubMed:29053855).

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-3
  3. Target

    Gamma-aminobutyric acid receptor subunit alpha-5

    go.drugbank.com/bio_entities/BE0000471
    TargetHumans

    Alpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:14993607, PubMed:29961870, PubMed:30140029

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-5
  4. Target

    Gamma-aminobutyric acid receptor subunit alpha-1

    go.drugbank.com/bio_entities/BE0000795
    TargetHumans

    Alpha subunit of the heteropentameric ligand-gated chloride channel gated by Gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:23909897, PubMed:25489750, PubMed:29950725 … GABAARs containing alpha-1 and beta-2 or -3 subunits exhibit synaptogenic activity; the gamma-2 subunit being necessary but not sufficient to induce rapid synaptic contacts formation (PubMed:23909897,

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1
  5. Target

    Gamma-aminobutyric acid type B receptor subunit 1

    go.drugbank.com/bio_entities/BE0000217
    TargetHumans

    Component of a heterodimeric G protein-coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:15617512, PubMed:18165688, PubMed:22660477, PubMed:24305054, PubMed:36103875, PubMed:9872316, PubMed:9872744). Within the heterodimeric...

    Polypeptides: Gamma-aminobutyric acid type B receptor subunit 1
  6. Target

    Gamma-aminobutyric acid type B receptor subunit 2

    go.drugbank.com/bio_entities/BE0002340
    TargetHumans

    Component of a heterodimeric G protein-coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:15617512, PubMed:18165688, PubMed:22660477, PubMed:24305054, PubMed:9872316, PubMed:9872744). Within the heterodimeric GABA receptor, o...

    Polypeptides: Gamma-aminobutyric acid type B receptor subunit 2
  7. Pathway

    Gamma-Aminobutyric Acid Biosynthesis

    smpdb.ca/view/SMP0125090
    Metabolic

    GABA is transported into a synaptic vesicle by Vesicular inhibitory amino acid transporter. The vesicle is activated by calcium entering the presynapse as well as cAMP.

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 more
    Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid type B receptor subunit 1
  8. Target

    GABA(A) Receptor

    go.drugbank.com/bio_entities/BE0004797
    TargetHumans

    Pi subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA) (PubMed:10462548). … Gamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (By similarity).

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-2Synonyms: GABAAR subunit gamma-1, GABAAR subunit gamma-2
  9. Target

    GABA(A) Receptor Benzodiazepine Binding Site

    go.drugbank.com/bio_entities/BE0008668
    TargetHumans

    Gamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (By similarity). … Gamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790).

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit gamma-1Synonyms: GABAAR subunit gamma-1, GABAAR subunit gamma-2
  10. Target

    GABA(B) Receptor

    go.drugbank.com/bio_entities/BE0010194
    Target

    Component of a heterodimeric G protein-coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:15617512, PubMed:18165688, PubMed:22660477, PubMed:24305054, PubMed:36103875, PubMed:9872316, PubMed:9872744). Within the heterodimeric...

    Polypeptides: Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2