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D-Glyceric Aciduria
smpdb.ca/view/SMP0125705DiseaseD-Glyceric aciduria is an extremely rare inherited inborn error of metabolism (IEM) of serine and fructose metabolism. It is an autosomal recessive disorder that is caused by a defect in the D-glycerate kinase (GLYCTK) gene. GLYCTK codes...
Drugs: NADH · ATP · sn-glycerol 3-phosphate · Flavin adenine dinucleotide · Palmitic Acid · Glycerin +1 moreFamotidine H2 Anti-Histamine Action Pathway
smpdb.ca/view/SMP0126789Drug actionFamotidine is a histamine H2 receptor antagonist used to treat gastroesophageal reflux disease and various ulcers. Famotidine displays high selectivity towards H2 histamine receptors compared to other H2 anti-histamines. After being take...
Drugs: ATP · Famotidine · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphateDiphenhydramine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145416Drug actionDiphenhydramine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines in...
Chlorpheniramine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145427Drug actionChlorpheniramine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines i...
Bromhexine Predicted Metabolism Pathway
smpdb.ca/view/SMP0174838MetabolicMetabolites of Bromhexine are predicted with biotransformer.
Diphenhydramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174902Drug actionDiphenhydramine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, al...
Chlorpheniramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174950Drug actionChlorpheniramine is a histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Chlorpheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175042Drug actionChlorpheniramine is a histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Galactose Metabolism
smpdb.ca/view/SMP0000043MetabolicThis pathway depicts the conversion of galactose into glucose, lactose, and other sugar intermediates that may be used for a range of metabolic process. Dietary sources of galactose are numerous, but some of the primary sources in the hu...
Famotidine Action Pathway
smpdb.ca/view/SMP0000231Drug actionFamotidine (also known as Pepcid) can bind and inhibit histamine H2 receptor on parietal cell's basolateral membrane. Binding of famotidine can effectively inhibit the histamine effects, which lead to reduced nocturnal gastric acid and b...