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Displaying results 3051 - 3060 of 10000 in total
  1. Target

    Nucleotide triphosphate diphosphatase NUDT15

    go.drugbank.com/bio_entities/BE0009809
    EnzymeHumans

    Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:22556419 … Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low.

    Synonyms: Nucleoside diphosphate-linked to another moiety X hydrolase 15
  2. Indication

    Burns first degree

    go.drugbank.com/conditions/DBCOND0015343
    Drugs: Centella asiatica · Nepidermin · Pheniramine · St. John's Wort · Zinc oxide
    Synonyms: Erythema due to burn (first degree), unspecified site
  3. Indication

    Cognitive Dysfunctions

    go.drugbank.com/conditions/DBCOND0063316
    Drugs: Choline alfoscerate · Ginkgo biloba · Piracetam · Pyritinol
    Synonyms: Mild neurocognitive disorder due to known physiological condition
  4. Indication

    Osteoporosis caused by Glucocorticoid Treatment

    go.drugbank.com/conditions/DBCOND0129307
    Drugs: Alendronic acid · Denosumab · Nandrolone · Raloxifene · Teriparatide · Zoledronic acid
    Synonyms: Osteoporosis due to corticosteroids (disorder)
  5. Indication

    Rickettsial infectious disorders

    go.drugbank.com/conditions/DBCOND0027750
    Drugs: Doxycycline
    Synonyms: Disease due to Genus Rickettsia
  6. Drug

    AMG 108

    go.drugbank.com/drugs/DB05545
    Investigational

    AMG 108 was investigated for use as an antirheumatic agent.

  7. Drug

    Norclozapine

    go.drugbank.com/drugs/DB05766
    Investigational

    ACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA as a novel, stand-alone therapy for schizophrenia.

  8. Drug

    Polyethylene glycol 300

    go.drugbank.com/drugs/DB11161
    Approved

    Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. … Low molecular weight glycols are observed to exhibit antibacterial properties as well. PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes.

    Synonyms: PEG 300, Macrogol 300
  9. Indication

    Activated PI3 kinase delta syndrome

    go.drugbank.com/conditions/DBCOND0156285
    Drugs: Leniolisib
    Synonyms: Autosomal dominant immunodeficiency due to activated p110-delta syndrome
  10. Indication

    Acute Rheumatic Fever

    go.drugbank.com/conditions/DBCOND0063952
    Drugs: Benzylpenicillin · Tetracosactide
    Synonyms: Acute arthritis due to acute rheumatic fever