Search

Displaying results 31 - 40 of 135483 in total
  1. Pathway

    Levomethadyl Acetate Metabolism Pathway

    smpdb.ca/view/SMP0000638
    Drug metabolism

    Levomethadyl Acetate is metabolized by cytochrome P450 3A4 in two N-demethylation reactions to nor-levomethadyl acetate (nor-LAAM) and subsequently to dinor-levomethadyl acetate (dinor-LAAM). … It is an opioid agonist that has been used as an analgesic and to treat opioid dependence.

    Drugs: NADH · Levacetylmethadol · Mesoheme · Formaldehyde
  2. Pathway

    Methadyl Acetate Action Pathway

    smpdb.ca/view/SMP0000678
    Drug action

    The binding of methadyl acetate will eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter. … Therefore, methadyl acetate can reduce nerve conduction and decrease neurotransmitter release; so that perception of pain signals can be blocked.

    Drugs: ATP · Norepinephrine · Dopamine · Potassium cation · Calcium · Methadyl acetate
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1
  3. Pathway

    Cortisone Acetate Action Pathway

    smpdb.ca/view/SMP0126207
    Drug action

    Cortisone acetate is a steroid hormone approved by the FDA since 1950. … Cortisone acétate also affects the promoter of annexin-1, an important inflammatory protein as it affects leukocytes and blocks phospholipase A2 which reduces the amount of arachidonic acid being cleaved

    Drugs: Glutathione · Hydrocortisone · Dinoprostone · Calcium · Cortisone acetate · Prostaglandin D2 +4 more
  4. Pathway

    Eslicarbazepine Acetate Action Pathway

    smpdb.ca/view/SMP0126272
    Drug action

    Some side effects of using eslicarbazepine acetate may include dizziness, nausea, headache, and aphasia. … Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled

    Drugs: Potassium cation · Calcium · Mesoheme · Eslicarbazepine acetate · Eslicarbazepine
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent T-type calcium channel subunit alpha-1G
  5. Pathway

    Segesterone acetate Action Pathway

    smpdb.ca/view/SMP0126542
    Drug action

    Segesterone acetate binds selectively to progesterone receptors. … Segesterone acetate is not active when taken orally, but it is proved to be an anti-ovulatory agent when given in implants, vaginal rings, or percutaneous gel.

    Drugs: NADH · ATP · Progesterone · Testosterone · Estrone · Potassium cation +9 more
  6. Pathway

    Potassium acetate Drug Metabolism

    smpdb.ca/view/SMP0130496
    Metabolic

    Potassium acetate passes through the liver and is then excreted from the body mainly through the kidney. … Potassium acetate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Potassium acetate
  7. Pathway

    Magnesium acetate tetrahydrate Drug Metabolism

    smpdb.ca/view/SMP0130537
    Metabolic

    Magnesium acetate tetrahydrate passes through the liver and is then excreted from the body mainly through the kidney. … Magnesium acetate tetrahydrate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Magnesium acetate tetrahydrate
  8. Pathway

    Desoxycorticosterone acetate Predicted Metabolism Pathway

    smpdb.ca/view/SMP0174880
    Metabolic

    Metabolites of Template6MB2 are predicted with biotransformer.

    Drugs: Midodrine · Mesoheme · Desoxycorticosterone acetate
  9. Pathway

    Levomethadyl Acetate Action Action Pathway

    smpdb.ca/view/SMP0000677
    Drug action

    However, levomethadyl acetate is more active and more toxic than morphine. … Levomethadyl acetate can also open calcium-dependent inwardly rectifying potassium channels (OP1 receptor agonist) to reduce neuronal excitability as well as lead to hyperpolarization.

    Drugs: ATP · Norepinephrine · Dopamine · Levacetylmethadol · Potassium cation · Calcium
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1
  10. Pathway

    Estradiol acetate Predicted Metabolism Pathway

    smpdb.ca/view/SMP0174628
    Metabolic

    Metabolites of Estradiol acetate are predicted with biotransformer.

    Drugs: Mesoheme · Estradiol acetate