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Calcium carbonate
go.drugbank.com/drugs/DB06724ApprovedInvestigationalCalcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. … An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also be used as a nutritional supplement or to treat hypocalcemia.
Mixtures: Calcium Folic Acid Plus D Chewable, PNV Ferrous Fumarate Docusate Folic AcidCategories: ascorbic acid (vit C) and calcium, Antacids and AdsorbentsPralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigational[L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell lung cancer, breast cancer, and bladder cancer.[A246678] … [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes.
Categories: Folic Acid Analogues, Folic Acid AntagonistsSynonyms: N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid, (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acidDL-alpha tocopheryl acetate
go.drugbank.com/drugs/DB14477ApprovedMixtures: Iron Polysaccharides Folic Acid DHA, PNV Ferrous Fumarate Docusate Folic AcidCategories: Vitamin E, VitaminsCholecalciferol Vitamin D Action Pathway
smpdb.ca/view/SMP0125002Drug actionVitamin D3 (Cholecalciferol) is a form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis … Calcitriol interacts with vitamin D receptors in the small intestine to enhance the efficiency of intestinal calcium and phosphorous absorption from about 10-15% to 30-40% and 60% increased to 80%, respectively
Enzymes: Vitamin D 25-hydroxylase, Vitamin D3 receptor2-Hydroxyglutric Aciduria (D and L Form)
smpdb.ca/view/SMP0000136DiseaseA deficiency in this enzyme results in accumulation of D-2-Hydroxyglutaric acid in plasma, spinal fluid, and urine; oxoglutaric acid in urine; and gabba-aminobutyric acid in spinal fluid. … A deficiency in this enzyme results in accumulation of L-2-Hydroxyglutaric acid in plasma, spinal fluid, and urine; and L-lysine in plasma and spinal fluid.
Drugs: Pyridoxal phosphate · Pyruvic acid · Biotin · Aspartic acid · L-Glutamine · Adenosine phosphate +17 moreEnzymes: N-acetyl-D-glucosamine kinaseAlpha Linolenic Acid and Linoleic Acid Metabolism
smpdb.ca/view/SMP0000018MetabolicLNA enters the cell and is catalyzed to gamma-linolenic acid (GLA) by acyl-CoA 6-desaturase (delta-6-desaturase/fatty acid desaturase 2). … Both LNA and ALA are essential dietary requirements for all mammals since they cannot be synthesized natively in the body.
Enzymes: Fatty acid desaturase 1, Fatty acid desaturase 2Calcium and Vitamin D Deficiencies
go.drugbank.com/conditions/DBCOND0077928Synonyms: Calcium and Vitamin D DeficienciesMetabolism and Physiological Effects of Oxalic acid
smpdb.ca/view/SMP0124875MetabolicGlycine and hydroxyproline comes from protein sources in the diet such as red meat and eggs. Glycine Is converted into glyoxylate in the peroxisome by the enzyme d-amino acid oxidase. … Glyoxylate is generated through glycine and hydroxyproline catabolism and can be converted to oxalate. In humans, this process takes place in the liver.
Drugs: Pyridoxal phosphate · Ascorbic acid · Succinic acid · Glutamic acid · Glycine · Proline +4 moreEnzymes: D-amino-acid oxidase, Sodium- and chloride-dependent transporter XTRP3Metabolsim and Physiological Effects of Argininic acid
smpdb.ca/view/SMP0125504MetabolicArginnosuccinate is synthesized from citrulline and aspartic acid by the enzyme argininosuccinate synthase. That is catalyzed by argininosuccinate lyase to produce arginine and fumaric acid. … Glutamic acid is carboxylated into 1-Pyrroline-5-carboxylic acid by the enzyme Delta-1-pyrroline-5-carboxylate synthase. 1-Pyrroline-5-carboxylic acid with glutaric acid synthesize Oxoglutaric acid and
Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 moreEnzymes: D-amino-acid oxidase, Neutral amino acid transporter ADeficiency, Vitamin D
go.drugbank.com/conditions/DBCOND0044543Drugs: Ascorbic acid · Calcium · Calcium citrate · Cholecalciferol · Cod liver oil · Ergocalciferol +3 moreSynonyms: D Vitamin Deficiency, Vitamin D-deficient