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Displaying results 4691 - 4700 of 10000 in total
  1. Pathway

    Sialuria or French Type Sialuria

    smpdb.ca/view/SMP0125712
    Disease

    Sialuria is caused by mutation in the gene encoding uridinediphosphate-N-acetylglucosamine 2-epimerase (UDP-GlcNAc 2-epimerase, which causes an excessive synthesis of sialic acid (N-acetylneuraminic acid, NeuAc). This causes accumulation...

    Drugs: Pyruvic acid · L-Glutamine · N-Acetylglucosamine · Glutamic acid · ATP · Glucosamine +7 more
  2. Indication

    Fever

    go.drugbank.com/conditions/DBCOND0020923
    Drugs: Acetaminophen · Acetylsalicylic acid · Ascorbic acid · Brompheniramine · Caffeine · Chlorpheniramine +20 more
    Synonyms: Has a temperature
  3. Target

    Uncharacterized MFS-type transporter EfpA

    go.drugbank.com/bio_entities/BE0009715
    TargetMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

    Synonyms: Efflux protein A
  4. Indication

    Febrile Illness Acute

    go.drugbank.com/conditions/DBCOND0059951
    Drugs: Acetaminophen
    Synonyms: Has a temperature
  5. Drug

    Nimesulide

    go.drugbank.com/drugs/DB04743
    ApprovedWithdrawn

    Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

    Mixtures: NIMOKAIN %1 + %5 JEL, 50 G, SULIDIN PLUS %1 + %5 LIKIT JEL, 30 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0125788
    Disease

    Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them. … A defect in this enzyme results in decrease of levels of retinal and vitamin A in serum; Signs and symptoms include night blindness, poor adaptation to darkness, dry skin and hair.

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
  7. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. … [A215412] Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]

    Mixtures: Tukol A, Supress ACategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Sigma-1 Agonist
  8. Drug

    Amlodipine

    go.drugbank.com/drugs/DB00381
    ApprovedInvestigational

    Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. … Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than

    Synonyms: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylateInternational brands: Atecard-AM, Amlodipine 5
  9. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0000336
    Disease

    Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them. … A defect in this enzyme results in decrease of levels of retinal and vitamin A in serum; Signs and symptoms include night blindness, poor adaptation to darkness, dry skin and hair.

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
  10. Target

    ATP-dependent 6-phosphofructokinase, muscle type

    go.drugbank.com/bio_entities/BE0012586
    TargetHumans

    Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis

    Synonyms: PFK-A, 6-phosphofructokinase type A