Search
Metabolism and Physiological Effects of Kynurenine
smpdb.ca/view/SMP0125524DiseaseIn the blood it travels to the liver and is transported into a hepatocyte by an amino acid transporter. … Tryptophan is consumed through foods such as milk, eggs, chicken, turkey, and oats. Tryptophan is then transported from the small intestine into the blood by an amino acid transport.
Enzymes: Neutral and basic amino acid transport protein rBAT, Neutral amino acid transporter AMetabolism and Physiological Effects of Isovalerylglycine
smpdb.ca/view/SMP0126748MetabolicIsovalerylglycine (IVG) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. … In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation.
Metabolism and Physiological Effects of Tiglylglycine
smpdb.ca/view/SMP0126840MetabolicIn certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. … Tiglylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism.
Enzymes: Branched-chain-amino-acid aminotransferase, mitochondrial, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrialMetabolism and Physiological Effects of Citrulline
smpdb.ca/view/SMP0126861MetabolicIn addition, citrulline and L-aspartic acid can be converted into argininosuccinic acid through the action of the enzyme argininosuccinate synthase. … wax beans, and potato.
Metabolism and Physiological Effects of Putrescine
smpdb.ca/view/SMP0123276MetabolicPutrescine is an aliphatic amine that is formed through gut microbial metabolism from the amino acid arginine which is acquired from foods that are high in protein. … While putrescine is important for interactions and processes involving, DNA, RNA and proteins, at high levels it is also a protein bound uremic toxin found in the body that can inhibit erythropoietin production
Metabolism and Physiological Effects of Xanthosine
smpdb.ca/view/SMP0124866MetabolicThe purines are guanine and adenine. These undergo metabolism in the liver to form xanthosine. Adenine forms adenosine through the enzyme purine nucleoside phosphorylase. … Xanthosine then enters the blood where it can have detrimental effects on other organs such as the kidney, causing renal failure and the heart causing cardiovascular disease.
Metabolism and Physiological Effects of Uridine
smpdb.ca/view/SMP0124871MetabolicMore specifically, uridine is a nucleoside consisting of uracil and D-ribose and a component of RNA. … L-glutamine is first converted to carbamoyl phosphate then to N-Carbamoyl-L-aspartate and finally to dihydroorotate by the CAD protein (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and
Enzymes: Neutral amino acid transporter B(0)Metabolism and Physiological Effects of p-Cresol sulphate
smpdb.ca/view/SMP0126850MetabolicUremic toxins include other low-molecular-weight compounds such as indoxyl sulfate, 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid, and asymmetric dimethylarginine. … p-Cresol sulfate is a microbial metabolite that is found in urine and likely derives from secondary metabolism of p-cresol.
D-Arginine and D-Ornithine Metabolism
smpdb.ca/view/SMP0000036MetabolicD-Amino acids have been show to be present in high concentrations in humans and play a role in biological functions. … DAAO is highly specific towards D-amino acids and favours free neutral D-amino acids or those with hydrophobic, polar or aromatic groups. Acidic amino acids are not catalyze by DAOO.
Enzymes: D-amino-acid oxidaseMetabolism and Physiological Effects of Phenylacetylglutamine
smpdb.ca/view/SMP0123208Metabolicacid. … It has been shown that over 50% of urine phenylacetylglutamine may be derived from kidney conjugation of free plasma phenylacetic acid and/or from the kidney's preferential filtration of conjugated phenylacetic
Drugs: Phenylalanine · L-Glutamine · Adenosine phosphate · ATP · Magnesium cation · Phenylpyruvic acid +1 moreEnzymes: Y+L amino acid transporter 1, Excitatory amino acid transporter 3