Search

Displaying results 51 - 60 of 427 in total
  1. Pathway

    Cystathionine beta-Synthase Deficiency

    smpdb.ca/view/SMP0125678
    Disease

    Cystathionine Beta-Synthase Deficiency (CBS Deficiency; Homocystinuria) is an autosomal recessive disease caused by a mutation in the CBS gene which codes for cystathionine beta-synthase. A deficiency in this enzyme results in accumulati...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1
  2. Pathway

    Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)

    smpdb.ca/view/SMP0125682
    Disease

    Methylenetetrahydrofolate reductase deficiency (MTHFRD; Homocystinuria due to defect of n(5,10)-methylene THF deficiency) is caused by a defect in the MTHFR gene which codes for methylenetetrahydrofolate reductase. Methylenetetrahydrofol...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1
  3. Drug

    Glutamic acid

    go.drugbank.com/drugs/DB00142
    ApprovedInvestigationalNutraceutical

    A peptide that is a homopolymer of glutamic acid.

    Mixtures: Glutamic Acid HCl Betaine HCl W Pepsin, Glutamic Acid Pepsin and Betaine Tablets
  4. Target

    Gamma-butyrobetaine dioxygenase

    go.drugbank.com/bio_entities/BE0002197
    TargetEnzymeHumans

    Catalyzes the formation of L-carnitine from gamma-butyrobetaine

  5. Target

    Choline dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0000636
    EnzymeHumans

    Catalyzes the dehydrogenation of choline to betaine aldehyde in the mitochondria (By similarity). Involved in mitochondrial autophagy after mitochondrial damage (PubMed:25483962)

  6. Target

    Flavin-containing monooxygenase 3

    go.drugbank.com/bio_entities/BE0003606
    EnzymeHumans

    TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.

  7. Target

    Flavin-containing monooxygenase 1

    go.drugbank.com/bio_entities/BE0003609
    EnzymeHumans

    TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine

  8. Target

    Y+L amino acid transporter 2

    go.drugbank.com/bio_entities/BE0009872
    TransporterHumans

    May also transport glycine betaine in a sodium dependent manner from the cumulus granulosa into the enclosed oocyte (By similarity)

  9. Indication

    Diarrhea and Loose Stools

    go.drugbank.com/conditions/DBCOND0126047
    Drugs: Anise oil · Attapulgite · Bacillus clausii · Bifidobacterium longum infantis · Bismuth subsalicylate · Difenoxin +18 more
  10. Indication

    Hypochlorhydria

    go.drugbank.com/conditions/DBCOND0125063
    Drugs: Pepsin