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Displaying results 741 - 750 of 6831 in total
  1. Indication

    Acquired Coagulation Factor Deficiency

    go.drugbank.com/conditions/DBCOND0032166
    Drugs: Coagulation factor X human · Plasma protein fraction (human)
    Synonyms: Deficiency of coagulation factor due to liver disease (disorder), Deficiency of coagulation factor due to vitamin K deficiency (disorder)
  2. Target

    Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

    go.drugbank.com/bio_entities/BE0004448
    TargetHumans

    GSPT1/ERF3A mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site (PubMed:27863242). … GTP hydrolysis by GSPT1/ERF3A induces a conformational change that leads to its dissociation, permitting ETF1/ERF1 to accommodate fully in the A-site (PubMed:16777602, PubMed:27863242).

    Synonyms: G1 to S phase transition protein 1 homolog
  3. Indication

    Alcohol Problem Drinking

    go.drugbank.com/conditions/DBCOND0132393
    Drugs: Disulfiram
    Synonyms: [X]Mental and behavioral disorders due to use of alcohol: dependence syndrome, [X]Mental and behavioural disorders due to use of alcohol: dependence syndrome
  4. Indication

    Acute Ischemic Stroke

    go.drugbank.com/conditions/DBCOND0030034
    Drugs: Alteplase · Tenecteplase
    Synonyms: Acute cerebrovascular accident due to ischemia (disorder)
  5. Target

    Mitogen-activated protein kinase kinase kinase kinase 5

    go.drugbank.com/bio_entities/BE0009474
    TargetHumans

    May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway

    Synonyms: Kinase homologous to SPS1/STE20
  6. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

    Mixtures: TQ OFTAMOX D UD®, TQ OFTAMOX® D UDProducts: T & B, TQ OFTAMOX® UD
  7. Indication

    Anaemia vitamin B6 deficiency

    go.drugbank.com/conditions/DBCOND0007206
    Drugs: Mepivacaine
    Synonyms: Anemia due to vitamin B>6< deficiency (disorder)
  8. Indication

    Lacrimation

    go.drugbank.com/conditions/DBCOND0064848
    Drugs: Naphazoline
    Synonyms: Epiphora, unspecified as to cause
  9. Indication

    Ancylostoma duodenale infection

    go.drugbank.com/conditions/DBCOND0022060
    Drugs: Levamisole · Mebendazole
    Synonyms: Ancylostomiasis due to Ancylostoma duodenale
  10. Indication

    Malaria

    go.drugbank.com/conditions/DBCOND0007188
    Drugs: Acetyl sulfisoxazole · Artemether · Chloroquine · Hydroxychloroquine · Ivermectin · Primaquine +2 more
    Synonyms: Disease due to Plasmodiidae (disorder)