NCT05117567
Reducing Malaria Transmission in Forest-going Mobile and Migrant Populations in Lao PDR and Cambodia No drug interventions prevention Not Available unknown_status NCT00330902
Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan treatment 3 completed NCT02721186
Effectiveness of Mass Drug Administration for Reducing Seasonal Malaria Transmission in Zanzibar prevention Not Available completed NCT03719599
Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia No drug interventions Not Available Not Available completed NCT03931473
Efficacy of Two Dual Active Ingredient Long Lasting Insecticidal Nets for Control of Malaria Transmitted by Pyrethroid Resistant Vectors in Benin No drug interventions prevention Not Available completed NCT03937817
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants No drug interventions Not Available Not Available recruiting NCT04323306
A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533. No drug interventions treatment 1 completed NCT04966702
Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA) treatment 3 active_not_recruiting NCT05652504
Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1) No drug interventions prevention 1 suspended NCT05796193
Net Transition Initiative: Efficacy of Two Next-generation Nets for Control of Malaria in Cote D'Ivoire No drug interventions prevention Not Available active_not_recruiting NCT06607003
Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays No drug interventions basic_science 1 not_yet_recruiting NCT00001645
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection No drug interventions Not Available Not Available recruiting NCT02471378
Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates No drug interventions Not Available Not Available recruiting NCT02639299
Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge No drug interventions Not Available Not Available recruiting NCT05690841
FocaL Mass Drug Administration for Vivax Malaria Elimination No drug interventions prevention 3 not_yet_recruiting NCT01168271
Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali No drug interventions Not Available Not Available recruiting NCT03074435
Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire prevention 3 completed NCT03671109
Improving Maternal heAlth by Reducing Malaria in African HIV Women prevention 3 completed NCT05581641
Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria No drug interventions prevention 1 completed NCT06141057
A Study to Compare Two Dosing Regimens for a New Malaria Vaccine treatment 1 active_not_recruiting NCT04650815
Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso No drug interventions Not Available Not Available completed NCT04704674
Community Dynamics of Malaria Transmission in Humans and Mosquitoes in Fleh-la and Marshansue, Salala District, Bong County, Liberia No drug interventions Not Available Not Available active_not_recruiting NCT04969913
Community Dynamics of Malaria Transmission in Humans and Mosquitoes at Maferinyah Sub-Prefecture, Guinea No drug interventions Not Available Not Available active_not_recruiting NCT05400655
Anti-malaria MAb in Kenyan Children No drug interventions prevention 2 completed NCT05913973
Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults prevention 1 recruiting NCT06069544
A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination with an Investigational RNA-based Vaccine Against Malaria No drug interventions prevention 1 / 2 recruiting NCT06575647
Vivax Elimination With Tafenoquine (VET) Study treatment 4 not_yet_recruiting NCT06590597
Improving Knowledge, Attitudes and Practices for Malaria Prevention in the Embera Katio Population No drug interventions treatment Not Available completed NCT01240603
Plasmodium Falciparum Clearance Rates in Response to Artesunate in Eastern Cambodia No drug interventions Not Available Not Available completed NCT00341003
Severe Malaria and Anti-malarial Drug Resistance in Cambodia No drug interventions Not Available Not Available completed NCT00442403
Safety and Efficacy of Chloroquine Associated With Dehydroepiandrosterone Sulphate to Treat Uncomplicated Falciparum Malaria treatment 3 suspended NCT01154803
Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection No drug interventions prevention Not Available completed NCT00131703
Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women treatment 3 completed NCT05444790
Abbott NxTekTM Malaria RDT WHO Prequalification Study No drug interventions Not Available Not Available completed NCT00740090
Malaria Vaccine for Children in Mali prevention 1 completed NCT04148690
Assessing the Impact of Group Antenatal Care on IPTp Uptake in Tanzania No drug interventions health_services_research Not Available terminated NCT00317590
Effectiveness and Cost-Effectiveness of a Rapid Diagnostic Test for Malaria No drug interventions diagnostic 4 completed NCT02315690
Evaluation of Reactive Focal Mass Drug Administration for Malaria Elimination in Swaziland treatment 3 completed NCT04079621
Short Course Radical Cure of P. Vivax Malaria in Nepal treatment 4 completed NCT04069221
Absolute BA and OZ439 PK Effect of Different OZ439 Dose Volumes and Cobicistat Co-administration Study treatment 1 completed NCT00115921
Evaluation of Home-Based Management of Fever in Urban Ugandan Children No drug interventions treatment Not Available completed NCT03163121
Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers No drug interventions prevention 1 completed NCT01972321
ICCM of Common Childhood Diseases: Mozambique and Uganda No drug interventions health_services_research Not Available completed NCT05604521
A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI No drug interventions prevention 1 terminated NCT02488902
A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium Falciparum treatment 2 completed NCT01190202
Epidemiology Study of Malaria Transmission Intensity in Africa No drug interventions other Not Available completed NCT01052584
Ethiopia Malaria Therapeutic Efficacy Study treatment Not Available completed NCT01703884
ANC & Malaria Diagnostic in Pregnancy No drug interventions prevention 4 completed NCT00669084
Innate and Acquired Resistance to Plasmodium Falciparum Malaria in Mali No drug interventions Not Available Not Available completed NCT02517879
Community Point Distribution of Insecticide Treated Bed Nets No drug interventions prevention Not Available completed NCT02528279
Relapses in Plasmodium Ovale and Efficacy of Artemether-lumefantrine for Mixed Species and Non-falciparum Malaria other Not Available completed NCT01373879
AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Adults and Children in a Malaria Endemic Area No drug interventions prevention 1 completed NCT02900079
Use of Malaria Rapid Diagnostic Tests as a Decision Aid for the Management of Fever by International Travelers No drug interventions Not Available Not Available withdrawn NCT01785979
Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial Splenomegaly treatment 3 withdrawn NCT00342043
Examination of Protective Factors Against Severe Malaria No drug interventions Not Available Not Available completed NCT00167843
Reducing the Effects of Malaria in Children by Administering Repeated Preventive Doses prevention 4 completed NCT01697787
Amodiaquine-Artesunate & Artemether-Lumefantrine Efficacy in Burkina Faso treatment 4 completed NCT00158587
Eight Week Primaquine Regimen for the Treatment of Vivax Malaria treatment 3 completed NCT02083887
A Phase I Study to Assess the Safety and Immunogenicity of ChAd63 ME-TRAP - MVA ME-TRAP Heterologous Prime-boost Vaccination Co-administered With EPI Vaccines in Gambian Infants No drug interventions prevention 1 completed NCT04858087
Malawi International Center of Excellence in Malaria Research School-based Cohort No drug interventions Not Available Not Available completed NCT02013687
Safety and Immunogenicity of Plant-Derived Pfs25 VLP-FhCMB Malaria Transmission Blocking Vaccine in Healthy Adults No drug interventions prevention 1 completed NCT00870987
Clinical Trial for Malaria Vaccines to Test for Safety, Immune Response and Protection Against Malaria prevention 1 / 2 completed NCT05223933
Proactive Community Case Management (Pro-CCM) in Rural Madagascar No drug interventions health_services_research Not Available completed NCT02704533
Sequential Optimization of Dose and Schedule of PfSPZ Vaccine No drug interventions prevention 1 completed NCT02783833
MMV390048 and Its Antimalarial Activity Against Plasmodium Falciparum in Healthy Adult Subjects, Part B No drug interventions treatment 1 / 2 completed NCT06232954
Evaluation of the Protective Efficacy of a Spatial Repellent to Reduce Malaria Prevalence in Uganda No drug interventions prevention Not Available recruiting NCT03967054
Repeat Ivermectin Mass Drug Administrations for MALaria Control II prevention 3 active_not_recruiting NCT01645254
Phase 1b Malaria Clinical Trial Using Argemone Mexicana in Healthy Adults in Mali No drug interventions Not Available 1 unknown_status NCT01422954
Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis basic_science Not Available completed NCT01916954
Comparison of Two Regimens of Artemether-lumefantrine for the Treatment of Malaria in Pregnancy treatment 3 completed NCT05478954
Chemoprevention Efficacy Study in Burkina Faso prevention 4 active_not_recruiting NCT03341754
Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults No drug interventions prevention 1 completed NCT02511054
Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B... prevention 1 completed NCT04494854
Perceptions, Representations and Experiences of Malaria Prophylaxis in Patients Born in Endemic Areas and Living in France. No drug interventions Not Available Not Available completed NCT00469651
Phase Ib Trial of MSP3 LSP in Children in Tanzania prevention 1 unknown_status NCT00808951
In Vivo and in Vitro Efficacy of Antimalarial Treatments in Children in Burkina Faso treatment 4 completed NCT01603251
Trial of Artemether-Lumefantrine Alone and in Combination With Ivermectin to Reduce Post-Treatment Malaria Transmission treatment 1 / 2 completed NCT03217851
Prevalence Survey of Antimalarial Drug Resistance Markers No drug interventions Not Available Not Available completed NCT01397851
Stimulating Private Sector Malaria Control No drug interventions health_services_research Not Available completed NCT05084651
Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole treatment 1 completed NCT00217451
Treatment of Malaria in Gabon With Fosmidomycin-Clindamycin treatment 2 completed NCT02511353
Efficacy and Safety of High-dose Ivermectin for Reducing Malaria Transmission: A Dose Finding Study treatment 2 completed NCT06560853
Evaluation of a Comprehensive School Health Programme in Zambia No drug interventions health_services_research Not Available active_not_recruiting NCT05340153
Efficacy and Safety of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine in Cameroon treatment 4 unknown_status NCT04020653
A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria treatment 2 withdrawn NCT03707353
An Efficacy Study of IV Boosting With ChAd63/MVA ME-TRAP No drug interventions prevention 1 / 2 completed NCT02758353
The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria No drug interventions health_services_research Not Available completed NCT00367653
Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria. treatment 3 completed NCT02199977
Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector No drug interventions health_services_research Not Available completed NCT04370977
In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III) treatment 4 completed NCT01585077
Exposure of Naive and Pre-immune Subjects to P. Vivax Challenge No drug interventions basic_science 1 / 2 completed NCT00385047
A Study to Determine Whether 2 Investigational Malaria Vaccines Are Safe, Protective Against Malaria in Adults No drug interventions prevention 1 / 2 completed NCT03083847
Dose Escalation PfSPZ-CVac prevention 1 completed NCT01635647
A Phase 1/2b Study of an Investigational Malaria Vaccination Strategy in 5-17 Month Old Infants and Children in Burkina Faso prevention 1 / 2 completed NCT02927145
A Challenge Study to Assess the Safety, Immunogenicity and Efficacy of a Malaria Vaccine Candidate No drug interventions prevention 1 / 2 completed NCT01075945
Dihydroartemisinin- Piperaquine Versus Artemether- Lumefantrine in the Treatment Uncomplicated Plasmodium Falciparum Malaria in Sudan treatment 4 unknown_status NCT00119145
Kintampo Trial of Combination Therapy for Malaria treatment 4 completed NCT02914145
Mass Drug Administrations of DHA-PQP to Accelerate Towards Malaria Elimination in Magude District, Southern Mozambique treatment Not Available completed NCT02653898
Malaria Elimination Pilot Study in Military Forces in Cambodia prevention 4 unknown_status NCT00878098
Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa No drug interventions Not Available Not Available completed NCT00374998
Safety and Immunogenicity Study of the Malaria Vaccines FP9 PP and MVA PP No drug interventions prevention 1 completed NCT06166498
Parasite Clearance and Protection From Infection (PCPI) in Zambia prevention 3 recruiting NCT01958905
Efficacy and Bio-availability of Artemether-Lumefantrine in Severely Malnourished Children treatment Not Available completed NCT06044805
Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax treatment 4 completed NCT03035305
Seasonal Malaria Chemoprevention With or Without Lipid-based Nutrient Supplement in Children Aged 6-59 Months in Mali prevention Not Available completed NCT00878397
Impact of School-based Delivery of Long Lasting Insecticide Nets No drug interventions prevention Not Available completed NCT00341783
Assessment of Biologic Parameters in Preparation for Future Malaria Vaccine Trials in Don gu Bougou, Mali No drug interventions Not Available Not Available terminated NCT01862783
Collection of Biological Material From Pregnant Women in a Malarial Region No drug interventions Not Available Not Available terminated NCT01364883
Safety and Immunogenicity of Novel Vaccination Schedules With Malaria Vaccines AdCh63 ME-TRAP and MVA ME-TRAP No drug interventions prevention 1 completed NCT04230161
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda No drug interventions Not Available Not Available completed NCT01624961
Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immune Adults No drug interventions diagnostic 1 completed NCT04235361
Mobile Point of Care Diagnostic Testing for Ebola Virus Disease in DRC No drug interventions Not Available Not Available unknown_status NCT00132561
A Trial of Intermittent Treatment in the Prevention of Malaria in Senegalese Children prevention 2 / 3 completed NCT00454961
Effectiveness of Artemether-Lumefantrine for Malaria Treatment of Children at Community Level in Tanzania treatment 4 completed NCT01728961
Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy treatment 4 terminated NCT04724161
Antenatal Care as a Platform for Malaria Surveillance: Utilizing Community Prevalence Measures From the New Nets Project to Validate ANC Surveillance of Malaria in Mozambique No drug interventions Not Available Not Available completed NCT02118428
Clinical and Biological Efficacy of Mirasol-treated Fresh Whole Blood for the Prevention of Transfusion-transmitted Malaria No drug interventions prevention Not Available completed NCT02213211
School-based Programme of Malaria Diagnosis and Treatment in Southern Malawi treatment Not Available completed NCT05304611
Anti-malaria MAb in Malian Children No drug interventions prevention 2 completed NCT00720811
Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs treatment Not Available completed NCT03970993
VAC 072-An Efficacy Study of R21/MM in Different Dose Schedules prevention 1 / 2 completed NCT05287893
Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria other 1 completed NCT01450293
AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Children in a Malaria Endemic Area No drug interventions prevention 1 completed NCT02282293
Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE-BC2) prevention 3 completed NCT00565071
Parasite-based Diagnosis for Malaria in Uganda: Feasibility and Cost-Effectiveness No drug interventions diagnostic Not Available unknown_status NCT01190371
Have Malaria Infections in Kenya Become Less Responsive to Artemisinin Treatment? treatment 4 unknown_status NCT03483571
Dynamics of Subclinical Malaria: Preliminary Study No drug interventions Not Available Not Available completed NCT00121771
Malaria Candidate Vaccines FP9 Circumsporozoite (CS) and MVA CS in Adult Gambian Men prevention 1 completed NCT02151578
Home Management of Malaria and Pneumonia No drug interventions treatment 4 completed NCT06318078
Buikwe Electronic Community Health Information System Impact Study No drug interventions health_services_research Not Available recruiting NCT00269178
Cluster Randomized Trial of Peer Health Education in Malaria in The Gambia No drug interventions other 3 completed NCT02174978
Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults No drug interventions prevention 1 completed NCT02492178
Bio-availability of Rectal Artesunate in Children With Severe Falciparum Malaria basic_science 2 completed NCT00336388
Use of Rapid Diagnostic Tests for Malaria Case Management in Kenya No drug interventions diagnostic Not Available completed NCT02294188
Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Indonesia No drug interventions prevention Not Available completed NCT02181088
A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of New Plasmodium Falciparum Malaria Vaccine Candidates ChAd63 RH5 Alone and With MVA RH5 No drug interventions prevention 1 completed NCT00935688
Examination of ACT Implementation in a Vivax / Falciparum Co-endemic Area No drug interventions diagnostic 4 completed NCT00452907
ACT MALI: Treatment of Malaria Based on Combination Therapies treatment 4 completed NCT00436007
Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen prevention 2 completed NCT00878007
Impact of Malaria Prevention on Health and Education in Kenyan Schoolchildren No drug interventions treatment Not Available completed NCT00138307
Correlates of Protection in Ghana No drug interventions Not Available Not Available completed NCT04053907
P. Falciparum Infection Dynamics and Transmission to Inform Elimination No drug interventions diagnostic Not Available unknown_status NCT02215707
A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses No drug interventions prevention 1 completed NCT01292707
A Cluster-randomised Trial of Interventions to Improve Antimalarial Prescribing With Malaria Tests No drug interventions health_services_research Not Available completed NCT00373607
Efficacy and Safety of Dihydroartemisinin/Piperaquine (Artekin®) for the Treatment of Uncomplicated Malaria in Peru treatment 3 completed NCT00118807
Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children treatment 3 completed NCT06555809
Evaluation of Artesunate in Infants Being Treated for Severe Malaria Not Available Not Available not_yet_recruiting NCT01949909
Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A : Phase Ia/Ib prevention 1 completed NCT00120809
Intermittent Preventative Treatment With Sulfadoxine-Pyrimethamine in Gambian Multigravidae prevention 3 completed NCT00984256
Weekly Dosing of Malarone ® for Prevention of Malaria prevention 2 completed NCT05041556
Strengthening the Evidence for Policy on the RTS,S/AS01 Malaria Vaccine No drug interventions Not Available Not Available unknown_status NCT00811356
A First Time in Human Study in Healthy Volunteers to Investigate a New Medicine to Treat Malaria treatment 1 terminated NCT02940756
Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo treatment 4 completed NCT02742285
Lumefantrine in Venous Plasma Versus Dried Capillary Blood Spot other 4 completed NCT04558515
Automated Microscopy Evaluation Study No drug interventions Not Available Not Available completed NCT01545115
Study of the Environmental Factors Modulating Children Immune Response in Northern Senegal No drug interventions Not Available Not Available completed NCT03128515
Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas treatment 3 completed NCT01624337
Malaria Prevention Cambodia prevention Not Available terminated NCT03960632
Performance Evaluation of Malaria Plus RDTs No drug interventions Not Available Not Available unknown_status NCT04206332
Trial to Evaluate CIS43LS in Healthy Adults No drug interventions prevention 1 completed NCT02392832
Evaluation of Long-Lasting Microbial Larvicides in Reducing Malaria Transmission and Clinical Malaria Incidence No drug interventions other Not Available completed NCT05905432
Pan-Malaria Transmission-Blocking Vaccine AnAPN1 No drug interventions prevention 1 not_yet_recruiting NCT06392152
Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar treatment Not Available active_not_recruiting NCT00123552
Longitudinal Antimalarial Combinations in Uganda treatment 3 completed NCT02043652
Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, Brazil treatment Not Available completed NCT01350752
Research on the Economics of Artemisinin Combination Therapy (ACTs) for the Treatment of Malaria No drug interventions health_services_research Not Available completed NCT01697852
The Combined Use of Indoor Residual Spraying (IRS) and Long-lasting Insecticidal Nets (LLINs) for Malaria Prevention No drug interventions prevention 4 unknown_status NCT00144352
In-Vivo Response of P. Falciparum to Antimalarial Treatment in HIV-Infected and HIV-Uninfected Adults treatment 4 completed NCT04321252
Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects other 1 completed NCT02174900
Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM) treatment 2 / 3 completed NCT00513500
Zambia Integrated Management of Malaria and Pneumonia Study health_services_research Not Available completed NCT00869700
Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected Adults treatment 4 completed NCT02610400
Evaluation of Reactive Focal Mass Drug Administration (rfMDA) +/- Reactive Focal Vector Control (RAVC) in Namibia No drug interventions treatment 3 completed NCT01018459
Adenovirus Type 35 Based Circumsporozoite Malaria Vaccine in Burkina Faso No drug interventions prevention 1 completed NCT00944359
Impact of Preventive and Therapeutic Zinc Supplementation Programs Among Young Children No drug interventions prevention Not Available completed NCT02938975
Field Efficacy Of Insecticide Treated Uniforms And Skin Repellents for Malaria Prevention No drug interventions prevention 3 unknown_status NCT02671175
Post-discharge Malaria Chemoprevention(PMC) Study prevention 3 completed NCT02600975
A Study to Assess the Safety and Immunogenicity of a Malaria Vaccine Candidate, R21, Administered With AS01B No drug interventions prevention 1 completed NCT03695770
Evaluation of a New Malaria Control Strategy Amongst Gold Miners Working Illegally in French Guiana (Malakit) No drug interventions other Not Available completed NCT06300970
Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia treatment 4 completed NCT06516042
Targeted Antimalarial Drug Administration for Seasonal Migrant Populations in Amhara Region, Ethiopia prevention 3 not_yet_recruiting NCT00442442
Clinical Evaluation of Mosquito Coils to Control Malaria in China No drug interventions prevention 3 unknown_status NCT00259142
Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies treatment Not Available terminated NCT00772642
Immune Parameters in the Cord Blood of Newborns Exposed to Malaria in the Womb No drug interventions Not Available Not Available completed NCT00292942
Study of the Safety of Intravenous Artesunate treatment 1 completed NCT02554799
A Study to Evaluate the Pharmacokinetics of Oral Formulations of MMV390048 Administered Fasted to Healthy Volunteers No drug interventions basic_science 1 completed NCT00977899
Phase 1 Study of the Safety and Immunogenicity of a Malaria Transmission-blocking Pfs25-Pfs25 Conjugate Vaccine No drug interventions prevention 1 withdrawn NCT02242799
Dolutegravir Interactions With Artemisinin-based Combination Therapies treatment 1 completed NCT02708199
Molecular Assessment of Drug Resistance Markers in Asymptomatic Malaria Cases and Malaria Antibody Kinetic No drug interventions Not Available Not Available completed NCT02699099
Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. prevention 3 completed NCT02885506
A FIH Study to Investigate the Safety, Tolerability and PK of P218 No drug interventions treatment 1 completed NCT02083406
Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP) treatment 1 completed NCT06173206
Parasite Clearance and Protection From Infection (PCPI) in Cameroon prevention 3 recruiting NCT00444106
Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function treatment 4 completed NCT02903706
Prevalence of Malaria Parasites in People Working in Illegal Gold Mining in French Guiana No drug interventions Not Available Not Available completed NCT00739206
Study of SAR97276A in the Treatment of Uncomplicated and Severe Malaria in Adults and Children. No drug interventions treatment 2 terminated NCT00075049
Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria No drug interventions prevention 1 / 2 completed NCT02532049
A Clinical Trial to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 Pfs25-IMX313 and MVA Pfs25-IMX313 No drug interventions prevention 1 completed NCT00414336
Phase I Study of Safety and Immunogenicity of AMA1-C1Alhydrogel + CPG 7909 Vaccine for Malaria prevention 1 completed NCT03824236
A Study to Evaluate the Efficacy, Immunogenicity and Safety in a Sporozoite Challenge Model of a Fractional Booster Dose of GSK Biologicals' Candidate Malaria Vaccine Administered to Previously Vaccinated Healthy Malaria-naïve Adults No drug interventions prevention 2 completed NCT02533336
The Effectiveness of Non-Pyrethroid Insecticide-Treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania prevention 3 terminated NCT03689036
Transmission Dynamics of Residual and Re-emerging Malaria in the Amazon: Defining a Roadmap to Malaria Elimination No drug interventions Not Available Not Available unknown_status NCT02793336
Early Life Cohort in Papua Indonesia (ELIPI Study) No drug interventions Not Available Not Available completed NCT02645513
Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi No drug interventions health_services_research Not Available completed NCT02810613
Leiden University Medical Center Mini Donor Bank No drug interventions Not Available Not Available withdrawn NCT00351013
The Use of Homeopathic-Based Treatment Approaches to Reduce the Prevalence of Malaria in Depressed Communities No drug interventions prevention 4 completed NCT01816113
Phase Ia Study of ChAd63/MVA PvDBP No drug interventions prevention 1 completed NCT00349713
FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, Mali prevention 1 completed NCT02996513
Assessing Model Parameters for Applying the Retinol Isotope Dilution (RID) Method No drug interventions diagnostic Not Available completed NCT01921413
Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT) No drug interventions Not Available Not Available completed NCT03576313
Mass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Malaria Elimination prevention 3 completed NCT05934318
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE) No drug interventions prevention Not Available not_yet_recruiting NCT00489619
Safe Pregnancy by Infectious Disease Control No drug interventions Not Available Not Available completed NCT02817919
Cohort Event Monitoring in Sub Saharan Africa No drug interventions Not Available Not Available completed NCT05746819
An MRI Ancillary Study of a Malaria Fever Investigation No drug interventions Not Available Not Available completed NCT01958619
Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers treatment 1 completed NCT00890019
A Study of AdCh63 ME-TRAP Alone and With MVA ME-TRAP prevention 1 completed NCT01669941
Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya prevention 4 completed NCT02880241
MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria No drug interventions treatment 2 terminated NCT05205941
MMV533 Plasmodium Falciparum Volunteer Infection Study No drug interventions treatment 1 completed NCT03707041
Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model No drug interventions prevention 1 completed NCT04570241
Mobilization at the Level of Schools on the Behavioral Change in Favor of the Fight Against Malaria in Mbandjock No drug interventions prevention Not Available unknown_status NCT02858817
Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis prevention 1 completed NCT00169117
A Stitch in Time May Save Lives: Turning Poor Bednets Into Good Ones No drug interventions prevention Not Available completed NCT00238017
Efficacy and Safety of Amodiaquine and Amodiaquine-Artesunate treatment 4 unknown_status NCT01743417
Computerized Cognitive Rehabilitation in Children After Severe Malaria No drug interventions treatment Not Available completed NCT05317117
Evaluating the Clinical Performance and Usability of Novel Malaria RDTs in Brazil No drug interventions diagnostic Not Available unknown_status NCT00126217
Revaccination of Young Children With Bacille Calmette Guerin (BCG) Vaccine prevention 4 terminated NCT05426434
Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy prevention 3 active_not_recruiting NCT04456634
Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Ruxolitinib With Artemether-lumefantrine treatment 1 completed NCT02963324
Physiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers basic_science 1 completed NCT00258024
Control of Pregnancy Associated Malaria With Intermittent Preventive Treatment No drug interventions prevention Not Available completed NCT03705624
P. Falciparum Infection Dynamics and Transmission to Inform Elimination (INDIE-1a) No drug interventions diagnostic Not Available completed NCT01651416
Seasonal Malaria Chemoprevention Versus Home Management of Malaria in Children Under 5 Years in Ghana prevention 4 completed NCT01976416
Novel Use Of Hydroxyurea in an African Region With Malaria treatment 3 completed NCT02482116
A Comparison of Diagnostic Approaches for Malaria and Pneumonia No drug interventions Not Available Not Available unknown_status NCT01065116
Artemether-Lumefantrine (AL) Unit Dose Pre-packs Versus Blister Packs treatment 3 completed NCT05567016
CHILD (Child Health and Infection With Low Density) Malaria No drug interventions prevention Not Available active_not_recruiting NCT02601716
PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults No drug interventions prevention 2 completed NCT00948896
Chemopreventive Therapy for Malaria in Ugandan Children prevention 3 completed NCT02473796
Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT No drug interventions health_services_research Not Available completed NCT00146796
A Randomised Trial of Rapid Diagnostic Tests in the Diagnosis of Malaria in Tanzania No drug interventions diagnostic 4 completed NCT01043796
Evaluation of Insecticide Treated Nets and Wall Liners for the Prevention of Malaria No drug interventions prevention 3 completed NCT01836458
A Study to Find the Minimum Inhibitory Concentration of KAE609 in Adult Male Patients With P. Falciparum Monoinfection treatment 2 completed NCT02903758
Frequency and Distribution of Mixed Falciparum-vivax Infections in French Guiana No drug interventions Not Available Not Available completed NCT01456858
Insecticide Treated Polyethylene Sheeting for Prevention of Malaria in Emergencies No drug interventions prevention 3 completed NCT00320658
Safety of and Immune Response to a Malaria Vaccine (MSP1 42-C1) With or Without CPG 7909 Adjuvant prevention 1 completed NCT00131235
Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth prevention 3 active_not_recruiting NCT05285735
Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants No drug interventions Not Available Not Available recruiting NCT00527163
Role of Nitric Oxide in Malaria No drug interventions Not Available Not Available completed NCT01867463
Testing Pfs25-EPA/Alhydrogel as a Potential Malaria Transmission Blocking Vaccine prevention 1 completed NCT01038063
Safety and Effectiveness of Artemisinin-based Combination Therapies (ACTs) With Repeated Treatments for Uncomplicated Falciparum Malaria Over a Three-year Period treatment 4 unknown_status NCT00984763
A Study to Assess Safety, Immunogenicity and Parasite Growth Inhibition of an Asexual Blood Stage Vaccine for P. Falciparum Malaria prevention 1 / 2 completed NCT01378286
Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria treatment 3 completed NCT01605786
Trial for Malaria Vaccine Candidate, PfPEBS (P. Falciparum Pre-Erythrocytic and Blood Stage) No drug interventions prevention 1 / 2 unknown_status NCT01024686
Phase 1/2a Trial of Pf GAP p52-/p36- Sporozoite Malaria Vaccine No drug interventions prevention 1 / 2 terminated NCT03641339
Defining Skin Immunity of a Bite of Key Insect Vectors in Humans No drug interventions basic_science Not Available completed NCT00206739
Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in Infants prevention 4 completed NCT00451139
Ototoxicity of Artemether / Lumefantrine (Coartem) and Other Antimalarials Not Available 4 completed NCT00167739
Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine treatment 4 completed NCT00261222
Efficacy of Amodiaquine in the Treatment of Uncomplicated Falciparum Malaria in Young Children of Burkina Faso treatment 2 completed NCT02793622
Prevention of Malaria in HIV-uninfected Pregnant Women and Infants prevention 3 completed NCT01666925
Efficacy of Malaria Vaccines in Kenyan Adults prevention 2 completed NCT05050825
Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal No drug interventions diagnostic Not Available unknown_status NCT01464125
Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in Adults treatment 2 unknown_status NCT01379430
Safety and Immunogenicity of AdCh63 ME-TRAP and MVA ME-TRAP Vaccines in Malaria Endemic Areas No drug interventions prevention 1 completed NCT06036030
Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West Papua treatment 2 completed NCT05816330
L9LS MAb in Malian Adults No drug interventions prevention 2 completed NCT02450630
Assessing the Effect of Strengthening Referral of Sick Children From the Private Health Sector and Its Impact on Referral Uptake in Uganda. No drug interventions health_services_research Not Available unknown_status NCT00682630
Bioequivalence Trial of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet treatment 1 completed NCT01232530
Pharmacovigilance for ACTs in Africa No drug interventions Not Available Not Available completed NCT04704830
R21/Matrix-M in African Children Against Clinical Malaria prevention 3 active_not_recruiting NCT02654730
Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia treatment 2 / 3 terminated NCT01443130
Chloroquine for Malaria in Pregnancy prevention 3 completed NCT01766830
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever) No drug interventions diagnostic Not Available completed NCT01465048
Optimisation of Controlled Human Malaria Infection Using Sporozoites Administered by Needle and Syringe No drug interventions Not Available Not Available completed NCT02389348
A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265 treatment 1 / 2 completed NCT01319448
Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease prevention 1 / 2 completed NCT01351948
Safety and Immunogenicity of Malaria Vaccines AdCh63 AMA1, MVA AMA1 and AMA1-C1/Alhydrogel®+/- CPG 7909 prevention 1 completed NCT02544048
Markers of T Cell Suppression: Antimalarial Treatment and Vaccine Responses in Healthy Malian Adults No drug interventions Not Available Not Available completed NCT00158548
ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan treatment 3 completed NCT01194557
Introducing Rapid Diagnostic Tests Into the Private Health Sector No drug interventions diagnostic Not Available completed NCT05856357
Perennial Malaria Chemoprevention (PMC) in Côte d'Ivoire Not Available Not Available recruiting NCT00466557
Plasmodium Resistance in A. Gambiae No drug interventions Not Available Not Available completed NCT01389557
Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra treatment 4 completed NCT01878357
Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine treatment 4 completed NCT00623857
Micronutrients and Child Health Study No drug interventions prevention 3 completed NCT00465257
Efficacy of Artesunate + Amodiaquine Four Years After Its Introduction in Zanzibar Not Available 4 suspended NCT03009526
Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi prevention 3 completed NCT00471666
Medical Implications of Coinfection With Malaria and Filariasis Parasites No drug interventions Not Available Not Available completed NCT00116766
Field Evaluation of Plant-based Mosquito Control No drug interventions prevention 2 completed NCT02458066
Trial to Compare Effectiveness of 2 Insecticides in Preventing Malaria No drug interventions prevention Not Available completed NCT04050566
Malaria Birth Cohort (MBC) in Agogo, Ghana No drug interventions Not Available Not Available recruiting NCT01936766
Optimal Fluid Management in Adult Severe Malaria No drug interventions Not Available Not Available completed NCT00137566
The Effect of Paracetamol in the Treatment of Non-severe Malaria in Children in Guinea-Bissau treatment 4 unknown_status NCT01142765
Study to Assess Efficacy of New Malaria Vaccine Candidates AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP & MVA ME-TRAP No drug interventions prevention 1 / 2 completed NCT05535465
Malaria Control : Improving Access to Prevention, Diagnostic and Care for Vulnerable Rural Communities No drug interventions health_services_research Not Available unknown_status NCT00130065
The Effect of Folic Acid on Efficacy of Sulfadoxine-pyrimethamine in Pregnant Women in Western Kenya treatment 4 completed NCT05219565
Evaluating ATSBs for Malaria Reduction in Kenya No drug interventions prevention Not Available completed NCT02878265
The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children No drug interventions prevention 3 completed NCT01658774
Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children treatment Not Available completed NCT00712374
Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal prevention 4 unknown_status NCT00399074
Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia prevention 3 completed NCT02389374
A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh treatment 4 completed NCT00290420
Prevention of P. Vivax Malaria During Pregnancy in Bolivia prevention 4 withdrawn NCT02605720
Cardiac Safety of Repeated Doses of Dihydroartemisinin-Piperaquine for the Use in Mass Treatment Campaigns treatment 3 completed NCT02613520
Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants No drug interventions prevention 1 completed NCT01899820
Evaluation of the Efficacy of Artemisinin Combination Therapy in Kenya treatment 3 unknown_status NCT00297882
Artemisinin-Based Combination Therapy: Clinical Trials in Cameroon treatment 3 completed NCT00538382
Study of Pharmacokinetics and Pharmacodynamics of Artesunate in Pregnant Women in the Democratic Republic of Congo Not Available 1 completed NCT05930782
Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers. No drug interventions prevention 1 completed NCT01955382
Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria treatment 2 completed NCT01935882
Low Dose Primaquine for Clearance of Gametocytes treatment 2 / 3 completed NCT00791531
Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers treatment 1 completed NCT01810731
Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya prevention 2 / 3 withdrawn NCT01663831
Repellents as Added Control Measure to Long Lasting Insecticidal Nets No drug interventions prevention Not Available completed NCT01836731
Impact Evaluation of Community-Based Health Programs in Rwanda No drug interventions prevention Not Available completed NCT00443131
Characterisation of the Immune Responses of 2 Experimental Malaria Vaccines No drug interventions prevention 2 completed NCT03897673
Optimizing Benefits While Reducing Risks of Iron in Malaria-endemic Areas No drug interventions prevention Not Available active_not_recruiting NCT02687373
Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya No drug interventions prevention 1 / 2 completed NCT05330273
Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz treatment 1 completed NCT03521973
Safety, Tolerability and Protective Efficacy of PfSPZ Vaccine in Gabonese Children No drug interventions prevention 2 completed NCT00421473
Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients prevention 4 completed NCT02590627
In-vivo Efficacy and Safety of Artemether/Lumefantrine Vs Dihydroartemisinin-piperaquine for Treatment of Uncomplicated Malaria and Assessment of Parasite Genetic Factors Associated With Parasite Clearance or Treatment Failure treatment 4 completed NCT02313376
Safety, Attenuation and Immunogenicity of GAP3KO Administered Via A Stephensi Mosquitoes No drug interventions basic_science 1 completed NCT00550160
The Synergistic Effects of Home-management and Intermittent Preventive Treatment of Malaria in Children health_services_research 4 completed NCT00209794
IPTi in Mozambican Infants for Malaria Prevention prevention 1 / 2 unknown_status NCT05788094
ACT vs CQ With Tafenoquine for P. Vivax Mono-infection treatment 4 recruiting NCT04157894
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Burkina Faso No drug interventions Not Available Not Available completed NCT02411994
Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria treatment 3 completed NCT03304691
Molecular Basis of Erythrocyte Invasion by Plasmodium Vivax Into Duffy-Negative Erythrocytes in Mali No drug interventions Not Available Not Available completed NCT03056391
Effect of Paracetamol on Renal Function in Plasmodium Knowlesi Malaria treatment 3 completed NCT01843491
A Phase I Clinical Trial Immunizing Healthy Adults With the NMRC-M3V-Ad-PfCA Vaccine to Generate Biologic Reagents No drug interventions health_services_research 1 withdrawn NCT02015091
Study of Controlled Human Malaria Infections to Evaluate Protection After Intravenous or Intramuscular Administration of PfSPZ Vaccine in Malaria-Naive Adults No drug interventions prevention 1 completed NCT02418962
Safety and Immunogenicity of Direct Venous Inoculation of a Radiation-attenuated PfSPZ Vaccine in Equatoguinean Adults No drug interventions prevention 1 completed NCT04788862
A Study of Blood-stage Controlled Human Plasmodium Falciparum Malaria Infection in Tanzania No drug interventions other Not Available completed NCT00285662
Intermittent Preventive Treatment (IPTi) for the Prevention of Malaria and Anaemia in PNG Infants No drug interventions prevention Not Available completed NCT01976780
In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy treatment 4 completed NCT00294580
Early Childhood Malaria Prevention With Maloprim in The Gambia No drug interventions prevention 4 completed NCT00354380
Safety and Efficacy of Methylene Blue Combined With Artesunate or Amodiaquine for Malaria Treatment in Children of Burkina Faso: a Pilot Study treatment 2 completed NCT02387580
Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets treatment 1 completed NCT01500980
Malaria Challenge in Healthy Volunteers prevention 1 completed NCT01231880
School Based Malaria Control in Ugandan Schoolchildren prevention 3 completed NCT05019729
Trial to Evaluate L9LS in Healthy Adults No drug interventions prevention 1 completed NCT00292929
Study of the Safety of Intravenous Artesunate treatment 1 completed NCT00125489
CQSP in Malawi: Chloroquine and Sulfadoxine-pyrimethamine Efficacy for the Treatment of Malaria in Malawi treatment 4 completed NCT01080989
The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands No drug interventions screening Not Available completed NCT04336189
Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda prevention 3 completed NCT01156389
Pyronaridine Artesunate-Ritonavir Drug-drug Interaction Study treatment 1 completed NCT02458092
Evaluate the Safety and Efficacy of Plasmodium Falciparum Malaria Protein 010 (FMP010) Administered With Adjuvant AS01B prevention 1 completed NCT00146692
A Trial of Improved Financial Access to Healthcare in Ghana No drug interventions treatment 4 completed NCT04102592
Getting Malaria "Off the Back" of Women and Children in Western Uganda No drug interventions prevention Not Available completed NCT04864444
Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities prevention Not Available completed NCT00424944
Safety of Recombinant Hybrid GMZ 2 [GLURP + MSP 3] Blood Stage Malaria Vaccine prevention 1 unknown_status NCT05471544
Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan prevention 3 active_not_recruiting NCT01228344
Surveillance of Effectiveness/Safety of Artemether-lumefantrine in Patients With Malaria No drug interventions Not Available Not Available completed NCT02298140
Providers' Compliance to Malaria Treatment No drug interventions health_services_research Not Available unknown_status NCT01210040
Long-term Iron Supplements and Malaria Risk in Early Pregnancy: a Randomized Controlled Trial No drug interventions supportive_care Not Available completed NCT01345240
Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) prevention 3 completed NCT00944840
Intermittent Preventive Treatment (IPTc) and Home Based Management of Malaria (HMM)in The Gambia prevention 3 completed NCT00384267
Congenital and Neonatal Malaria in Mali No drug interventions Not Available Not Available completed NCT00215267
The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda treatment Not Available completed NCT00519467
Safety and Efficacy Dose of Artesunate Used in Combination With LAPDAP Treatment of Uncomplicated Falciparum Malaria treatment 2 completed NCT06386367
Health Education by Buddhist Monks to Promote Malaria Knowledge and Preventive Practices in Rural Myanmar No drug interventions prevention Not Available completed NCT00432367
Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy treatment 3 completed NCT05644067
Assessment of the Malaria Vaccine Candidate SumayaVac-1 in Healthy Adults Aged 18-45 Years Living in a Malaria Endemic Country prevention 1 completed NCT01290601
Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults treatment 2 terminated NCT02329301
Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern Zambia treatment Not Available completed NCT01048801
Role and Effectiveness of Rapid Diagnostic Tests in Home-based Management of Malaria No drug interventions treatment Not Available completed NCT01782001
Evaluation of Vitamin A and Zinc Supplementation on Malarial Morbidity No drug interventions prevention 3 completed NCT05206201
A Study Of Zy-19489 Administered Via Oral Route To Investigate The Safety, Tolerability And Pharmacokinetics In Healthy Adult Human Subjects treatment 1 completed NCT03304704
Community Dynamics of Malaria Transmission and Mosquito Feeding in Bancoumana, Mali No drug interventions Not Available Not Available completed NCT04329104
Safety and Efficacy of CIS43LS Anti-malaria mAb in Mali No drug interventions prevention 2 completed NCT01341704
Proof-of-Concept Study of MSP3-LSP Vaccine to Protect Against Malaria in Africa prevention 2 completed NCT02563704
A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon treatment 3 completed NCT06578572
Seasonal R21 Mass Vaccination for Malaria Elimination No drug interventions prevention 3 recruiting NCT04315272
Gut and Azithromycin Mechanisms in Infants and Children II treatment 4 completed NCT01907672
The Role of Rapid Diagnostic Tests for Malaria for Targeting of ACTs at Community Level No drug interventions diagnostic 4 completed NCT04978272
Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP) prevention 3 active_not_recruiting NCT00978068
HIV Protease Inhibitors for the Prevention of Malaria in Ugandan Children prevention 3 completed NCT05874869
Dihydroartemisinin-piperaquine for Seasonal Malaria Chemoprophylaxis in Tanzania prevention Not Available completed NCT00346346
Analysis of the Immune Response to the Malaria Parasite in Mali, West Africa No drug interventions Not Available Not Available completed NCT05348746
ERASE - Impact of COVID-19 on Malaria Control No drug interventions Not Available Not Available unknown_status NCT00738946
A Trial of the Combined Impact of Intermittent Preventive Treatment and Insecticide Treated Bednets in Reducing Morbidity From Malaria in African Children No drug interventions prevention Not Available completed NCT06040346
Open-Label Study to Assess Meplazumab in Adult Patients Diagnosed With Plasmodium Falciparum treatment 2 recruiting NCT05400746
A Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UK prevention 0 unknown_status NCT01459146
Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana prevention 4 unknown_status NCT00380146
Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-pyrimethamine Intermittent Presumptive Treatment in Pregnant Women prevention Not Available completed NCT00663546
Malaria Studies in Cambodia No drug interventions Not Available Not Available completed NCT02119312
Malaria Clinical Trials Center General Screening No drug interventions Not Available Not Available completed NCT01119612
Prenatal Iron Supplements: Safety and Efficacy in Tanzania No drug interventions prevention Not Available completed NCT02909712
Cardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania basic_science 2 completed NCT01360112
Preventing the Spread of Malaria in Mali No drug interventions Not Available Not Available completed NCT01308112
Prenatal Iron and Malaria Study No drug interventions prevention 4 completed NCT03780712
Immune Dysfunction in Newborn Sepsis No drug interventions Not Available Not Available completed NCT04566510
LLIN Evaluation in Uganda Project No drug interventions prevention Not Available completed NCT00298610
Safety and Efficacy Study of IV Artesunate to Treat Malaria treatment 2 completed NCT05441410
Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults prevention 1 / 2 not_yet_recruiting NCT00114010
Experimental Vaccine for Malaria No drug interventions treatment 1 completed NCT00540410
Cohort Study in Senegal Comparing Artesunate + Amiodaquine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks treatment 4 completed NCT04368910
Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria treatment 3 terminated NCT00790881
Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected Adults treatment 4 completed NCT06278181
Diabetes, Metabolic Syndrome and Risk of Malaria in Cameroon No drug interventions Not Available Not Available recruiting NCT01374581
Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated Malaria treatment 3 completed NCT00687895
Improved Clinical and Microscopy Diagnosis at Primary Health Care in Tanzania No drug interventions health_services_research 4 completed NCT01133314
Artemether-Lumefantrine Effectiveness in Guinea-Bissau 2 No drug interventions Not Available Not Available completed NCT02294214
Spatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Tanzania No drug interventions prevention Not Available withdrawn NCT00563914
A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria treatment 1 / 2 completed NCT04601714
Baseline Cohort Malaria Morbidity Study No drug interventions Not Available Not Available completed NCT02793414
Diagnostic Utility of Volatile Organic Compounds in Human Breath for Acute Clinical Malaria in Ethiopia No drug interventions Not Available Not Available withdrawn NCT03162614
Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults No drug interventions prevention 2 completed NCT00203814
A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria treatment Not Available completed NCT00361114
IPT and Efficacy of Sulphadoxine/Pyrimethamine and Chlorproguanil/Dapsone in 6-59 Month Old Children With Malaria. treatment 3 terminated NCT01095055
A Study of AdCh63 AMA1 Alone and With MVA AMA1 prevention 1 completed NCT03199755
Dried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria treatment 2 withdrawn NCT00376155
Comparison of Two Strategies for the Delivery of IPTc prevention 4 completed NCT02431650
Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent treatment 1 / 2 completed NCT02374450
A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine No drug interventions Not Available Not Available completed NCT04666350
Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays Not Available Not Available completed NCT00341250
Malaria Vaccine in Children in Mali No drug interventions treatment 1 / 2 completed NCT02831023
Phase 2 Efficacy Study of Primaquine and Methylene Blue treatment 2 completed NCT01713608
A Dose-escalation Study to Investigate Safety and Toleration of OZ439 basic_science 1 completed NCT00431808
Safety and Immunogenicity of Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]) No drug interventions prevention 1 unknown_status NCT00863408
Estivation of Malaria Vector Mosquitoes in the Sahelian Region of Mali No drug interventions Not Available Not Available completed NCT02974608
Impact of Malaria on Pregnant Women in Ouelessebougou, Mali No drug interventions Not Available Not Available completed NCT03278808
Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis treatment 2 withdrawn NCT02592408
A Study to Assess Current Standard Malaria Treatment Guidelines in the Republic of the Sudan No drug interventions treatment 4 completed NCT01868438
Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy Volunteers treatment 1 completed NCT01445938
Anti-parasitic Activity and Safety Assessment of SAR97276A in Children With Uncomplicated Malaria treatment 2 terminated NCT00214643
Efficacy of Fosmidomycin-Clindamycin for Treating Malaria in Gabonese Children treatment 3 completed NCT03352843
Single Low-dose Primaquine Efficacy and Safety. prevention 4 completed NCT03874143
Clinical Evaluation of the Use of an mHealth Intervention on Quality of Care No drug interventions health_services_research Not Available completed NCT02925403
A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, With Matrix-M1 Adjuvant prevention 1 / 2 completed NCT00386503
Bioavailability of the Fixed Combination of Amodiaquine and Artesunate Under Fed & Fasted Conditions treatment 1 completed NCT03916003
Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas treatment 4 completed NCT01540903
Controlled Human Malaria Infection by Intradermal Injection of Plasmodium Falciparum Sporozoites in Tanzanian Adults No drug interventions diagnostic 1 completed NCT00549003
Efficacy and Cost Effectiveness of Malaria Diagnosis Procedures and the Rational Use of ACT in Zanzibar No drug interventions diagnostic 4 completed NCT01231503
Safety and Immunogenicity of GSK Biologicals' Malaria Vaccine 257049 When Administered on 7 Schedules to African Infants prevention 2 completed NCT02098590
Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection prevention Not Available completed NCT01328990
Pharmacokinetics of Sulfadoxine-pyrimethamine Plus Amodiaquine for Intermittent Preventive Treatment in Children (IPTc) prevention 1 / 2 completed NCT02788864
Prevention of Malaria With Dihydroartemisinine + Piperaquine for Forest Rangers prevention 4 completed NCT00327964
Rapid Diagnostic Tests (RDTs) for Malaria in Kampala, Uganda No drug interventions Not Available Not Available completed NCT01614964
Studies of a Candidate Aminoquinoline Antimalarial (AQ-13) treatment 2 completed NCT01954264
Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa No drug interventions other Not Available completed NCT00675064
Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects No drug interventions other 1 completed NCT00811421
Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy prevention Not Available completed NCT00307021
Double-blind Study of Safety and Immunogenicity of Two Candidate Malaria Vaccines in Gabonese Children No drug interventions prevention 2 completed NCT05323721
Effectiveness and Chemoprevention Efficacy of Implementing Seasonal Malaria Chemoprevention in Karamoja Region, Uganda prevention 4 active_not_recruiting NCT01713621
OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation treatment 2 completed NCT03203421
A Safety and Efficacy Study of ChAdOx1 LS2 and MVA LS2 No drug interventions prevention 1 / 2 completed NCT00917202
Efficacy of Methylene Blue for Malaria Treatment in Adults of Burkina Faso: Proof of Principle Study in Semi-Immune Adults of Burkina Faso in the Frame of the A8 Project of the SFB 544 No drug interventions Not Available 2 completed NCT00719602
Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAART treatment 0 completed NCT03989102
Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Malaria Transmission Season in Healthy African Adult Women of Childbearing Potential in Mali No drug interventions prevention 2 completed NCT04072302
Safety and Causal Prophylactic Efficacy of KAF156 in a Controlled Human Malaria Challenge Model prevention 1 completed NCT00471302
Normal Immunological Parameters Among Healthy Volunteers in Kambila, Mali No drug interventions Not Available Not Available completed NCT02118402
Iron and Prebiotics Fortification in Kenyan Infants No drug interventions basic_science Not Available completed NCT02836002
Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1 other 1 / 2 completed NCT01523002
Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate treatment 1 completed NCT01838902
Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers treatment 3 completed NCT00840502
Ultrasound Study in Pregnant Women With Malaria No drug interventions Not Available Not Available completed NCT00312702
Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America No drug interventions prevention 1 / 2 completed NCT03594084
Malaria in Strasbourg University Hospital No drug interventions Not Available Not Available unknown_status NCT00372684
PALUREA: Severe Imported Malaria in Adults No drug interventions Not Available Not Available completed NCT00422084
Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients treatment 3 completed NCT02230579
Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers No drug interventions treatment 1 completed NCT00393679
Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children treatment 3 completed NCT00938379
Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR prevention 3 unknown_status NCT05155579
Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines prevention 1 active_not_recruiting NCT00414479
Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment Not Available Not Available completed NCT05736679
EaveTubes for Vector Control No drug interventions prevention Not Available active_not_recruiting NCT00510679
Study of Post-Training Supports for Health Workers in Benin No drug interventions health_services_research Not Available completed NCT03208179
Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa prevention 3 completed NCT04766879
Spatial Repellents for the Prevention of Malaria in Kenya No drug interventions prevention Not Available completed NCT02898779
Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1 basic_science 1 completed NCT04716387
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Mozambique No drug interventions Not Available Not Available completed NCT05086887
Infections in Migrants in Sweden - the Importance of Malaria and Other Parasitic Infections No drug interventions Not Available Not Available unknown_status NCT04002687
Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ) No drug interventions prevention 1 completed NCT04245033
Evaluation of the Implementation and Effectiveness of Intermittent Preventive Treatment for Malaria Using Dihydroartemisinin-piperaquine on Reducing Malaria Burden in School Aged Children in Tanzania prevention 4 unknown_status NCT01002833
Comparison of Three Plasmodium Falciparum Isolates in an Experimental Human Malaria Infection No drug interventions basic_science Not Available completed NCT00832754
Restricting the Use of Artesunate Plus Amodiaquine Combination Therapy to Malaria Cases Confirmed by a Dipstick Test: A Cluster Randomised Control Trial No drug interventions treatment 4 completed NCT03917654
Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali prevention 2 completed NCT03496454
Susceptibility of Gambian Adults to PfSPZ-Challenge Infection in the Controlled Human Malaria Infection Model No drug interventions basic_science Not Available completed NCT02199951
Introduction of Eurartesim® in Burkina Faso, Mozambique, Ghana and Tanzania Not Available Not Available unknown_status NCT01627951
Comparison of Three Plasmodium Falciparum Isolates in a Controlled Human Malaria Infection No drug interventions basic_science Not Available completed NCT02206451
Assessing Human-to-Mosquito Transmission in Volunteers Participating in Malaria Vaccine Candidate Trials in Mali No drug interventions Not Available Not Available completed NCT02658253
Trial to Evaluate the Safety and Immunogenicity of a Placental Malaria Vaccine Candidate (PRIMVAC ) in Healthy Adults prevention 1 completed NCT03420053
Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian Adults No drug interventions prevention 1 completed NCT02297477
The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in Cambodia treatment 4 unknown_status NCT00465777
Improved Management and in-Hospital Mortality No drug interventions health_services_research Not Available completed NCT00857077
Intermittent Preventive Treatment for Malaria in Infants in Navrongo Ghana prevention Not Available completed NCT02942277
Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali prevention 1 completed NCT04672577
Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and Malaria No drug interventions Not Available Not Available not_yet_recruiting NCT02163447
Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants prevention 3 completed NCT03334747
Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria. treatment 2 completed NCT04238845
Assessment of a Combined Strategy of SMC + Nutrients Supplementation to Tackle Malaria and Malnutrition No drug interventions prevention Not Available unknown_status NCT01449045
Trial of Malaria Seasonal IPTc Combined With Community Case Management prevention 3 completed NCT00127998
Antimalarial Drug Resistance in Mali treatment Not Available completed NCT04545905
Antenatal Care as a Platform for Malaria Surveillance: Utilizing Community Prevalence Measures From the New Nets Project to Validate ANC Surveillance of Malaria in Burkina Faso No drug interventions Not Available Not Available completed NCT02527005
A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients prevention 1 completed NCT04241705
Evaluation of Targeted Mass Drug Administration for Malaria in Ethiopia No drug interventions prevention Not Available unknown_status NCT02866097
Integrated Community Case Management Study in Eastern Province, Zambia No drug interventions health_services_research Not Available unknown_status NCT01157897
Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults No drug interventions prevention 1 / 2 completed NCT02394197
Effectiveness of Malaria Treatment in Mexico treatment 4 completed NCT06225297
Evaluation of a Package of Interventions to Reduce the Burden of Malaria in the Urban Daaras of Touba, Senegal No drug interventions prevention 4 active_not_recruiting NCT05958797
TES of Chloroquine for Pv in the Philippines in 2016 Not Available Not Available completed NCT04695197
Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso treatment 3 completed NCT01902797
Malaria Survey in the Tak Province Refugee Camps No drug interventions diagnostic Not Available completed NCT00146783
Navrongo Drug Options for IPT in Pregnancy Trial prevention 2 / 3 completed NCT01002183
Fosmidomycin With Clindamycin or With Clindamycin Plus Artesunate treatment 2 withdrawn NCT04816461
Boosting the Impact of SMC Through Simultaneous Screening and Treatment of Roommates prevention 4 unknown_status NCT00308061
Safety Study of Candidate Malaria Vaccine FMP1/AS02A in Healthy Adults in Bandiagara, Mali prevention 1 completed NCT00158561
Chlorproguanil/Dapsone Compared With Chloroquine and SP for Vivax Malaria Not Available 3 completed NCT02461628
Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector (Aim 2) No drug interventions health_services_research Not Available completed NCT00197028
Examine Safety and Immune Responses of GSK 257049 Vaccine When Administered to Infants Living in a Malaria-endemic Region prevention 2 completed NCT04558528
Innovation Platform No drug interventions Not Available Not Available completed NCT02672228
Feasibility of the Vapor Nanobubble Technology for Malaria Diagnostics (MalariaSense) No drug interventions diagnostic Not Available completed NCT00375128
Sporozoite Challenge of Polyprotein Vaccinees No drug interventions prevention 1 / 2 completed NCT00380393
Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children. prevention 2 completed NCT04966871
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults No drug interventions prevention 1 completed NCT00497471
RCT Iron Supplementation and Malaria Chemoprophylaxis for Prevention of Severe Anemia and Malaria in Tanzanian Infants prevention Not Available terminated NCT00126971
Chlorproguanil-Dapsone in Pregnant Women treatment 1 suspended NCT00852371
Intermittent Preventive Treatment of Malaria in Schoolchildren prevention 3 completed NCT00169078
Impact of Insecticide-treated Curtains on Antimalarial Drug Resistance treatment Not Available completed NCT00461578
Tolerability and Efficacy of CD+A Compared to AQ+SP for the Treatment of P.Falciparum Malaria in Rwandan Children treatment Not Available completed NCT03512678
Evaluation of a Digital Microscope for Malaria No drug interventions Not Available Not Available completed NCT01205178
G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine) basic_science 1 completed NCT05123378
Liberia National Community Health Assistant (NCHA) Program and Under-five Mortality No drug interventions prevention Not Available unknown_status NCT01115478
Malaria in Pregnancy: Nutrition and Immunologic Effects No drug interventions prevention Not Available completed NCT04222088
TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014 Not Available Not Available completed NCT02793388
A Trial on Supervised Primaquine Use in Ethiopia treatment 4 withdrawn NCT00452088
A Phase Ib Trial of MSP 3 LSP in 1-2 Year Old Children in Burkina Faso prevention 1 unknown_status NCT02572388
A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, Administered With and Without Matrix-M1 prevention 1 completed NCT00844207
A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine health_services_research 1 completed NCT04428307
Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Kenya No drug interventions health_services_research Not Available completed NCT01265407
Malaria Surveillance in Rakai, Uganda No drug interventions Not Available Not Available completed NCT05979207
Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum No drug interventions treatment 1 completed NCT02800109
Child Follow-up Until 2 Years No drug interventions Not Available Not Available completed NCT01383109
Human Mass Balance Study of Pyronaridine treatment 1 completed NCT01160809
Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia No drug interventions prevention 4 completed NCT02627456
Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites in Healthy African Adults in Mali prevention 1 completed NCT00453856
Efficacy of Sulfadoxine-Pyrimethamine for Treating Malaria in Gabonese Children treatment 4 terminated NCT00871156
Tafenoquine/Chloroquine DDI Study other 1 completed NCT00941785
Dihydroartemisinin (DHA)-Piperaquine for IPT to Prevent Malaria in Children in Burkina Faso prevention 2 / 3 completed NCT00541385
Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients treatment 3 completed NCT01717885
Antimalarial Pharmacology in Children and Pregnant Women in Uganda No drug interventions Not Available Not Available completed NCT04428385
Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria No drug interventions health_services_research Not Available completed NCT05058885
Plasmodium Vivax Among Duffy Negative Population in Cameroon. No drug interventions Not Available Not Available recruiting NCT00289185
Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian Infants prevention 2 completed NCT04228315
Biomarkers of P. Vivax Relapse treatment Not Available recruiting NCT02009215
School-Based Treatment With ACT to Reduce Transmission prevention 4 completed NCT01166815
Zinc Supplementation to Reduce Diarrhea Rates in Adults in Western Kenya. No drug interventions prevention 2 / 3 completed NCT05978037
A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines prevention 1 / 2 recruiting NCT00243737
Efficacy, Safety and Pharmacokinetic of ArtequinTM P. Falciparum Malaria treatment 2 completed NCT06529237
Malaria Molecular Surveillance in Mozambique (Phase 2) No drug interventions Not Available Not Available recruiting NCT02288637
Evaluation of a Novel Long Lasting Insecticidal Net and Indoor Residual Spray Product No drug interventions prevention Not Available completed NCT02431637
Experimental Falciparum Transmission to Anopheles No drug interventions treatment 1 completed NCT01805232
Intravenous Artesunate and Malaria treatment 4 unknown_status NCT00119132
Effectiveness of Intermittent Preventive Treatment for Malaria in Children prevention 2 / 3 completed NCT00680732
Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component prevention 4 completed NCT06179732
Field Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities prevention 3 completed NCT00522132
Phase II Artesunate Study in Severe Malaria treatment 2 completed NCT03224052
Empirical ANtibiotic THErapy in Adults Hospitalised With Malaria No drug interventions Not Available Not Available completed NCT01454752
Intermittent Parasite Clearance (IPC) in Schools: Impact on Malaria, Anaemia and Cognition No drug interventions prevention Not Available completed NCT05889052
Perennial Malaria Chemoprevention (PMC) in Cameroon Not Available Not Available recruiting NCT00231452
Age of Exposure and Immunity to Malaria in Infants Not Available Not Available completed NCT00287300
Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women prevention Not Available completed NCT02878200
RHOST-cRCT, Reactive Household-based Self-administered Treatment Against Residual Malaria Transmission treatment Not Available completed NCT00527800
Interactions Between HIV and Malaria in African Children treatment 3 completed NCT04839900
Proactive Community Case Management for Malaria in Zambia No drug interventions treatment Not Available completed NCT06225700
Clinical Validation of Novel Malaria Diagnostic Tools for POC Point-of-Care Testing No drug interventions Not Available Not Available completed NCT01148459
Safety and Immunogenicity of GSK Biologicals' Investigational Malaria Vaccine in HIV Infected Infants and Children prevention 3 completed NCT05286359
Performance Evaluation of Malaria Plus Rapid Diagnostic Tests (RDTs) for the Detection of Plasmodium Infections in Patients With Symptoms Suggestive of Malaria No drug interventions diagnostic Not Available completed NCT01755559
Efficacy of Three ACTs for the Treatment of Falciparum Malaria in Maradi Niger treatment 4 completed NCT01853475
Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted State treatment 1 completed NCT00323375
Studies of AQ-13, a Candidate Aminoquinoline Antimalarial, in Comparison With Chloroquine basic_science 1 completed NCT00229775
Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the Philippines treatment Not Available completed NCT00652275
Immunogenicity, Efficacy and Safety Study of an MSP3-LSP (Long Synthetic Peptide) Malaria Vaccine prevention 2 unknown_status NCT00336375
Treatment of Uncomplicated Childhood Malaria in Tanzania by Artemether+Lumefantrine - Efficacy and Genotyping treatment 4 completed NCT04478370
Characterizing Humoral Immune Response to Mosquito Bites No drug interventions basic_science Not Available recruiting NCT02556242
Targeted Indoor Residual Spraying Against Malaria No drug interventions prevention 4 completed NCT05946642
Innovative Intermittent Preventive Treatment Approaches to Reduce Malaria Burden in School-age Children in Burkina Faso prevention 3 recruiting NCT06122142
Spatial Repellents for Malaria Control No drug interventions prevention Not Available not_yet_recruiting NCT00440999
Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria treatment 3 completed NCT02414399
Azithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children treatment 4 active_not_recruiting NCT01023399
Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire treatment 4 completed NCT00561899
Comparison of Three Drug Combinations for Intermittent Treatment of Malaria in Children prevention 2 / 3 completed NCT04844099
Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell Anaemia prevention 3 completed NCT00716599
Training in Fever Case Management With Rapid Diagnostic Tests (RDTs) for Malaria in Uganda No drug interventions diagnostic Not Available completed NCT02132299
Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults No drug interventions prevention 1 completed NCT02491606
Evaluation of Weekly Tafenoquine treatment 2 completed NCT00397449
GMZ2-Aluminum Hydroxide Phase I, Tübingen No drug interventions prevention 1 unknown_status NCT03542149
Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP other 1 completed NCT05891236
Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults No drug interventions prevention 1 recruiting NCT00203736
A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria treatment Not Available completed NCT01988636
Study of Safety and Effectiveness of Intravenous Immunization With PfSPZ Vaccine in Healthy African Adults No drug interventions prevention 1 completed NCT05072613
Monitoring Pregnant Women for Antimalarial Drug Resistance No drug interventions Not Available Not Available completed NCT01084213
Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy health_services_research 4 completed NCT01575613
Reducing the Burden of Malaria by Targeting Hotspots of Malaria Transmission prevention Not Available completed NCT04778813
Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) treatment 4 unknown_status NCT00347113
Schistosome and Intestinal Worm Infections and Malaria Morbidity Among School and Pre-school Children in, Tanzania prevention Not Available completed NCT01082718
Pharmacokinetics of Mefloquine-Artesunate in Pregnant Women With Uncomplicated Plasmodium Falciparum Infection treatment 2 / 3 withdrawn NCT00146718
Anti-Malarial Drug Resistance in Cameroon treatment 2 / 3 completed NCT03399318
Aggressive Antipyretics for Fever Reduction in CNS Malaria treatment 2 completed NCT02504918
Markers of T Cell Suppression: Associations With Malaria Infection and Antimalarial Treatment in Malian Children No drug interventions Not Available Not Available completed NCT04897919
Effectiveness and Safety of Artemether + Lumefantrine and Dihydroartemisinin + Piperaquine for Treating Malaria treatment 4 completed NCT02905019
A Safety and Efficacy Study of R21 +/- ChAd63/MVA ME-TRAP prevention 1 / 2 completed NCT06468319
Pregnancy Registry in Mali No drug interventions Not Available Not Available recruiting NCT00866619
Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in Africa prevention 3 completed NCT04622241
Uganda Housing Modification Study No drug interventions prevention Not Available unknown_status NCT00197041
A Study to Evaluate the Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Malaria Vaccine RTS,S/AS02A, When Administered to Children Aged 1 to 4 Years Living in a Malaria-endemic Region of Mozambique. No drug interventions prevention 2 completed NCT01082341
Immunization of Human Volunteers With P. Vivax Irradiated Sporozoites No drug interventions prevention 1 / 2 completed NCT01524341
Efficacy, Safety, Tolerability and Pharmacokinetics of KAE609 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection treatment 2 completed NCT01086917
Experimental Human Malaria Infection by PfSPZ No drug interventions Not Available 1 completed NCT04529434
Star Homes Project 2 No drug interventions prevention Not Available recruiting NCT02910934
Cost-effectiveness Evaluation of Vector Control Strategies in Mozambique No drug interventions health_services_research Not Available completed NCT01722734
Preserving ACTs - Text Reminders to Increase Adherence to ACT Treatment No drug interventions supportive_care Not Available completed NCT03641534
Monitoring of Perfusion in Sepsis and Malaria No drug interventions Not Available Not Available completed NCT00329134
Investigation of the Efficacy of Quinine Sulphate Administered Via Taste-Masked Pellets to Children With Falciparum Malaria treatment 2 completed NCT01366534
Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve Adults No drug interventions prevention 2 completed NCT02561624
Hati Salama (Secure Voucher) No drug interventions prevention Not Available completed NCT00544024
Mefloquine Bioequivalence Among 3 Commercially Available Tablets. No drug interventions Not Available Not Available completed NCT02741024
Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo treatment 4 completed NCT00356824
Relationship Between HIV and Malaria in Ugandan Children Not Available Not Available completed NCT02115516
Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chemoprophylaxis No drug interventions prevention 1 completed NCT00487916
Phase 1 Study of the Safety, Reactogenicity, and Immunogenicity of AMA1-C1/ISA 720: Blood Stage Vaccine for Plasmodium Falciparum No drug interventions prevention 1 completed NCT00144716
Evaluation of Combined Use of ITN's and Insect Repellents Against Malaria No drug interventions diagnostic 3 completed NCT00889616
Phase I Study of the Safety and Immunogenicity of BSAM-2/Alhydrogel +CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium Falciparum Malaria in Adults in the US and Mali prevention 1 completed NCT03554616
Efficacy of Three Novel Bi-treated Long Lasting Insecticidal Nets No drug interventions prevention Not Available completed NCT02207816
An Extension to Study MALARIA-055 PRI (NCT00866619) to Evaluate the Long-term Efficacy, Safety and Immunogenicity of GSK Biologicals' Candidate Malaria Vaccine in Infants and Children in Africa prevention 3 completed NCT04862416
Safety and Efficacy of R0.6C Vaccine No drug interventions prevention 1 completed NCT00445796
Arsucam® (Artesunate + Amiodaquine) Efficacy and TOLerance treatment 4 completed NCT01658696
Efficacy of Candidate Malaria Vaccines in Senegalese Adults prevention 2 completed NCT03599596
Monthly Versus Two Doses of Ante-Natal Intermittent Preventive Treatment With Sulphadoxine-Pyrimethamine prevention 1 unknown_status NCT02153996
Longitudinal Analysis of Plasmodium Falciparum-Specific Immunity in Travelers and Immigrants From Malaria Endemic Areas to the United States No drug interventions Not Available Not Available terminated NCT05979896
Chemoprevention Efficacy Study Nigeria prevention 4 recruiting NCT04708496
Optimizing Malaria Treatment for HIV-Malaria Co-infected Individuals treatment 4 unknown_status NCT01256658
A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®) treatment 4 completed NCT00819858
Effect of Ready to Use Therapeutic Food (RUTF) Supplement After an Episode of Malaria Falciparum on Weight No drug interventions prevention Not Available completed NCT00266058
Drug Interaction Study Between Antimalarial and Anti-HIV Medications Not Available 1 completed NCT03503058
Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria prevention 2 recruiting NCT06472258
Efficacy of Only IV Artesunate Versus IV Artesunate Plus IV Quinine in the Treatment of Severe Malaria in Children: A Comparative Study treatment Not Available completed NCT05354258
Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children prevention Not Available unknown_status NCT00274235
Intermittent Preventive Treatment During Pregnancy in Benin prevention 3 completed NCT00545935
Safety and Efficacy of Methylene Blue Combined With Amodiaquine or Artesunate for Malaria Treatment in Children of Burkina Faso treatment 2 completed NCT02739763
Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA) No drug interventions basic_science 1 unknown_status NCT01027663
Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium Falciparum No drug interventions basic_science Not Available completed NCT02692963
Safety and Protective Efficacy of BCG Vaccination Against Controlled Human Malaria Infection basic_science 2 completed NCT00386763
Efficacy and Safety of the Pediatric Formulation of Artemether- Lumefantrine in Children With Uncomplicated P. Falciparum Malaria. treatment 3 completed NCT00872963
An Extended Follow up of a RTS,S/AS01E Malaria Vaccine Trial Not Available Not Available unknown_status NCT00111163
Intermittent Preventive Treatment With Antimalarials in Kenyan Infants prevention Not Available completed NCT00425763
Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria No drug interventions prevention 4 completed NCT05186363
Effectiveness of Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Type Two Hybrid Implementation Study prevention 4 active_not_recruiting NCT02237586
Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ Challenge No drug interventions basic_science 1 completed NCT01939886
Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2) treatment 3 completed NCT04695886
Effectiveness of a Community-delivered Integrated Malaria Elimination (CIME) Model in Myanmar No drug interventions health_services_research Not Available unknown_status NCT01062386
Malaria Survey in Mbarara District, Uganda 2010 No drug interventions Not Available Not Available completed NCT03432039
Preventing Mental Health Problems After Childhood Severe Malaria No drug interventions prevention Not Available completed NCT02394522
Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM) No drug interventions prevention Not Available withdrawn NCT00120822
Folic Acid Supplementation in Gambian Primigravidae prevention 3 completed NCT03754322
LAMP Detection of Malaria in PREGnancy (LAMPREG) Trial No drug interventions diagnostic Not Available recruiting NCT01615822
Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers treatment 1 terminated NCT00493922
Trial of Rapid Diagnostic Tests in Rural Ghana No drug interventions diagnostic 4 completed NCT00323622
Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 Vaccine prevention 2 completed NCT02536222
Accelerating the Reduction of Malaria Transmission in Kanel, Ranérou and Linguère Districts No drug interventions Not Available 4 completed NCT00355225
Community-Effectiveness of the Distribution of Insecticide-Treated Bed Nets Through Social Marketing Antenatal Care Services in Malaria Control in Rural Burkina Faso No drug interventions educational_counseling_training Not Available completed NCT05605925
Ivermectin-artemisinin Combination Therapy for Eradication of Malaria prevention 4 recruiting NCT01994525
Immunization Via Mosquito Bite With Radiation-attenuated Sporozoites No drug interventions prevention 1 completed NCT00914225
Effect of Bednets and a Water Purification Device on HIV Disease Progression Among ART naïve Patients in Kenya No drug interventions Not Available Not Available completed NCT00378625
Efficacy, Effect on Gametocytes and Tolerability of the Addition of Artesunate to Amodiaquine in Colombia Not Available 3 completed NCT01976325
Evaluating the Ottawa Malaria Decision Aid No drug interventions prevention Not Available unknown_status NCT05391230
Permethrin-treated Baby-wraps for the Prevention of Malaria in Children No drug interventions prevention Not Available active_not_recruiting NCT04940130
PfSPZ Vaccine Trial in Malian Children No drug interventions prevention 2 completed NCT01517230
Can Mass Media Campaigns Reduce Child Mortality No drug interventions Not Available Not Available completed NCT05236530
Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir treatment 1 completed NCT00360230
Partially-blind (Observer-blind) Study of Safety and Immunogenicity of Two Malaria Vaccines in Ghanaian Children prevention 2 completed NCT06155448
Perennial Malaria Chemoprevention (PMC) Effect Study No drug interventions prevention Not Available active_not_recruiting NCT04795648
Spatial Repellents for Vector Control No drug interventions prevention Not Available completed NCT00132548
A Trial of Four Drug Regimens for the Prevention of Malaria in Senegalese Children prevention 3 completed NCT01054248
Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy treatment 3 completed NCT00168948
Intermittent Antimalaria Treatment With SP in African Children prevention 4 unknown_status NCT02698748
Evaluating the Role of Chloroquine for Malaria Elimination prevention 2 / 3 completed NCT01771848
Optimization of Controlled Human Malarial Infection by Injection of P. Falciparum Sporozoites in Non-Immune Adults No drug interventions diagnostic 1 completed NCT00137657
Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate Resistance educational_counseling_training 4 completed NCT02573857
A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection treatment 1 / 2 terminated NCT05149157
Trajectories and Mechanisms of Recovery From Malaria: An Observational Study No drug interventions Not Available Not Available recruiting NCT02259426
Dihydroartemisinin-piperaquine With Low Dose Primaquine to Reduce Malaria Transmission treatment 3 completed NCT02080026
Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis basic_science Not Available completed NCT01024426
Impact of Enhanced Health Facility Care in Uganda No drug interventions health_services_research 4 completed NCT06461026
L9LS MAb in Malian Infants No drug interventions prevention 1 recruiting NCT02659566
Impact of Antimalarial Treatment on Measures of T Cell Suppression/Regulation in Healthy Adults From Doneguebougou, Mali No drug interventions Not Available Not Available completed NCT04944966
Safety and Efficacy of Maytenus Senegalensis for the Treatment of Uncomplicated Malaria treatment 2 completed NCT05878366
Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC) No drug interventions other Not Available recruiting NCT00341666
Immune Response Regulation in People Infected Concurrently With Malarial and Filarial Parasites No drug interventions Not Available Not Available completed NCT00703066
Safety and Immunogenicity of 30 and 100 µg of GMZ2 in Gabonese Children Aged 1-5 Years prevention 1 unknown_status NCT00673166
Evaluation of Local Mechanisms for Staff Motivation to Reduce Hospital Mortality No drug interventions health_services_research Not Available completed NCT01002066
Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar No drug interventions Not Available Not Available completed NCT04419766
Evaluation of IR3535 as a Spatial Repellent for Malaria Control. No drug interventions prevention Not Available active_not_recruiting NCT04167566
Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children screening Not Available completed NCT01652365
Feasibility and Impact of Malaria Rapid Diagnostic Tests in the African Retail Sector No drug interventions health_services_research Not Available completed NCT01540474
Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive Adults treatment 1 completed NCT02694874
Rosiglitazone Adjunctive Therapy for Severe Malaria in Children treatment Not Available completed NCT03906474
VAC063C: A Study to Assess Repeat Blood-stage P. Falciparum Infection No drug interventions other Not Available completed NCT00158574
Kilimanjaro IPTi Drug Options Trial diagnostic 2 / 3 completed NCT02783820
Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A No drug interventions treatment 1 completed NCT00761020
Merozoite Surface Protein 1 Antibody Response in Asymptomatic Human Malaria Infection other Not Available completed NCT00529620
Three Alternative Drug Regimens for Malaria Seasonal Preventive Treatment in Senegal prevention 3 completed NCT01743820
Phase2a Primaquine Dose Escalation Study treatment 2 completed NCT05070520
Efficacy of Antimalarial Drugs Used for the Treatment of Uncomplicated Malaria, Plasmodium Falciparum, at the Agadez, Gaya and Tessaoua Sentinel Sites treatment 4 completed NCT00699920
Cohort Study in Uganda Comparing Artesunate + Amiodaquine (Coarsucam) Versus Artemether + Lumenfantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks treatment 4 completed NCT02721420
Delivery of Malaria Chemoprevention in the Post-discharge Management of Children With Severe Anaemia in Malawi prevention 3 unknown_status NCT01196520
Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM) No drug interventions Not Available Not Available completed NCT03523182
Spirulina Supplementation and Infant Growth, Morbidity and Motor Development No drug interventions treatment Not Available completed NCT01152931
Antioxidant Micronutrients in Malaria treatment 3 completed NCT00146731
A Trial of Antimalarial Drugs Used in Pregnancy in Tanzania treatment 3 completed NCT00993031
Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women prevention 3 completed NCT01082731
Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Falciparum in Pregnancy in Brazil treatment 4 terminated NCT01858831
Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone Suspension other 1 completed NCT01809873
Sustainable Financial Incentives To Improve Prescription Practices For Malaria No drug interventions health_services_research Not Available completed NCT02661373
First-in-Human Study of an Oral Plasmodium Falciparum Plasma Membrane Protein Inhibitor other 1 completed NCT00639873
Artemisinin Resistance in Bangladesh treatment Not Available completed NCT04265573
Feasibility, Acceptability and Costs of a Multiple First-lines Artemisinin-based Combination Therapies No drug interventions Not Available Not Available completed NCT04041973
Study to Assess Efficacy of Artemether-lumefantrine Prophylaxis Against Forest Malaria in Cambodia (PAL_Cambodia) prevention Not Available completed NCT01425073
Discontinuation of Trimethoprim-sulfamethoxazole Prophylaxis in Adults on Antiretroviral Therapy in Kenya No drug interventions treatment Not Available completed NCT04094727
Malaria High-Risk Populations in Namibia treatment 4 completed NCT01397227
A Study to Assess the Immunogenicity, Tolerability and Safety of a Malaria Vaccine and Also Its Protective Efficacy in a Malaria Challenge Model No drug interventions prevention 1 / 2 completed NCT00118027
A New Approach to Deliver Malaria Preventions to Pregnant Women at a Community Level in Uganda prevention Not Available completed NCT01214876
Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires No drug interventions Not Available Not Available completed NCT00499876
The Effect of Malaria on Disease Progression of HIV/AIDS supportive_care Not Available completed NCT06182176
Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control prevention Not Available not_yet_recruiting NCT00890760
A Study to Assess the Effectiveness of a New Malaria Vaccine Candidate by Infecting Vaccinated Volunteers With Malaria Parasites prevention 1 / 2 completed NCT03436160
Study Assessing Pharmacokinetics and Bioavailability of Three Novel Triazine Compounds No drug interventions diagnostic 0 completed NCT00455494
Food-Effect Bioavailability Study of AQ-13, a Candidate Antimalarial treatment 1 completed NCT00694694
Azithromycin + Artesunate v Artemether-lumefantrine in Uncomplicated Malaria. treatment 3 completed NCT00131794
Bacillus Calmette-Guerin (BCG) Vaccine and Morbidity From Malaria prevention 3 completed NCT00118794
Lapdap and Coartemether for Uncomplicated Malaria treatment 3 completed NCT02894294
Evaluation of Seasonal Malaria Chemoprevention in Kita No drug interventions Not Available Not Available completed NCT05950191
LLIN Evaluation in Uganda Project (LLINEUP3) No drug interventions prevention Not Available recruiting NCT00964691
A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands prevention 4 terminated NCT03281291
An Ancillary Study Protocol to GSK's Phase IIb Malaria Vaccine Trial Entitled "Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age" No drug interventions Not Available Not Available completed NCT03276962
Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age prevention 2 completed NCT06153862
Africa Ready Malaria Screening No drug interventions diagnostic Not Available active_not_recruiting NCT02334462
Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel , a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria, in Adults in the U.S. and Mali prevention 1 completed NCT03490162
Safety and Pharmacokinetics Study of DM1157 to Treat Malaria treatment 1 terminated NCT00766662
Intermittent Preventive Treatment in Infant in Mali health_services_research Not Available completed NCT01280162
Malaria Active Epidemiology and Treatment Study treatment Not Available completed NCT01450280
Safety and Immunogenicity of New Malaria Vaccine Candidate ChAd63 CS Administered Alone and With MVA CS No drug interventions prevention 1 completed NCT00367380
Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers No drug interventions basic_science 2 completed NCT02374580
Partnership and Dignity: a Mixed-methods Survey on Supporting and Retaining Uganda's Village Health Teams No drug interventions Not Available Not Available completed NCT00666380
A Study to Determine the Effects of an Investigational Malaria Vaccine Given to Adults Living in the United States and Thereafter to Adults Living in Kenya No drug interventions prevention 1 completed NCT02211729
A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children prevention 3 completed NCT00316329
ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria treatment 3 completed NCT02072629
HCU: Can VHVs Trained in ICCM Improve Care for Children No drug interventions health_services_research Not Available completed NCT03084289
A Study to Assess the Safety and Immunogenicity of a Candidate Malaria Vaccine Using Novel Routes of Administration No drug interventions prevention 1 completed NCT01546389
Sanaria™ PfSPZ Challenge Vaccine Not Available 1 completed NCT01157689
Artemether-Lumefantrine Effectiveness in Guinea-Bissau No drug interventions Not Available Not Available completed NCT01641289
Paracetamol Effect on Oxidative Stress and Renal Function in Severe Malaria treatment Not Available completed NCT00697892
Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug Combinations treatment 1 completed NCT01837992
Safety and Efficacy of Primaquine for P. Vivax treatment Not Available unknown_status NCT01043744
Non-malarial Febrile Illness in Children in Areas of Perennial Malaria Transmission treatment Not Available completed NCT03568344
Community Access to Rectal Artesunate for Malaria No drug interventions Not Available Not Available completed NCT01150344
Evaluation of the Riamet® Versus Malarone® in the Treatment of Uncomplicated Malaria treatment 4 completed NCT05085340
MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention Not Available Not Available recruiting NCT03590340
Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea No drug interventions prevention 1 completed NCT00197067
A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Candidate Vaccines RTS,S/AS02D (0.5 mL Dose) and RTS,S/AS02A (0.25 mL Dose) Administered IM According to a 0, 1, 2 Month Vaccination Schedule in Children Aged 3 to 5 Years Living in a Malaria-endemic Region of Mozambique. No drug interventions other 1 completed NCT05306067
Plasmodium Falciparum Genomic Intelligence in Mozambique No drug interventions Not Available Not Available completed NCT01441167
Experimental PfSPZ Vaccine in Adults Without Malaria No drug interventions prevention 1 completed NCT00427167
Phase I Study of AMA1-C1/Alhydrogel® (Registered Trademark) + CPG 7909 Malaria Vaccine prevention 1 completed NCT02600767
Artemether-lumefantrine for Treatment of P. Falciparum Malaria in Brazil treatment Not Available completed NCT02535767
Determining a Tolerable Dose of Primaquine in G6PD-deficient Persons Without Malaria in Mali treatment 1 / 2 completed NCT03996967
Diagnostic and Prognostic Biomarkers for Childhood Bacterial Pneumonia No drug interventions Not Available Not Available completed NCT01754701
Acute vs. Delayed Iron: Effect on Red Cell Iron Incorporation in Severe Malaria No drug interventions treatment Not Available completed NCT05085301
RapiGEN BIOCREDIT Malaria Ag RDTs WHO Prequalification Study No drug interventions Not Available Not Available completed NCT02294201
Spatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Kenya No drug interventions prevention Not Available withdrawn NCT00203801
Combination Antimalarials in Uncomplicated Malaria treatment Not Available completed NCT01728701
Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis No drug interventions prevention 1 completed NCT01845701
Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon treatment 3 completed NCT01511601
Apheresis to Obtain Plasma and White Blood Cells in Malies No drug interventions Not Available Not Available withdrawn NCT02251704
Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa No drug interventions other 4 completed NCT05218304
Baromètre Santé Adulte 2021-2022 No drug interventions other Not Available suspended NCT03384472
Malaria Genetic Surveillance in Cambodia No drug interventions Not Available Not Available completed NCT05095272
Blood-Stage Plasmodium Vivax Cell Bank No drug interventions other 1 completed NCT01165372
Study of Malaria Treatment at Phuoc Long Hospital, Binh Phuoc Province, Vietnam treatment 2 completed NCT01323972
Consistency of Immunogenicity and Non Inferiority of GSK Biologicals' Candidate Malaria Vaccine Lots in Children No drug interventions prevention 3 completed NCT02932072
Field Evaluation of a Device for Automated Malaria Microscopy (Autoscope Version 2) No drug interventions Not Available Not Available completed NCT01967472
Adherence to Antimalarial Drugs in Sierra Leone treatment Not Available completed NCT00978172
Safety and Efficacy Study of Artesunate and Mefloquin in Children With Uncomplicated Malaria treatment 4 completed NCT00408668
Efficacy of Combined PEV3A Virosomal Vaccine and FP9-MVA ME-TRAP Prime Boost Regimen prevention 1 / 2 completed NCT00225368
Effects of Insecticide Treated Bednets on Child Morbidity and Mortality No drug interventions prevention Not Available completed NCT02083068
Evaluation of the Protective Efficacy of a Vaccine Derived From the Synthetic CS Protein of Plasmodium Vivax basic_science 2 completed NCT02168569
In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children treatment 4 completed NCT00451269
Evaluation of Rapid Diagnosis Tests in Imported Malaria No drug interventions Not Available Not Available completed NCT03963869
Effectiveness of Malaria Camps as Part of the Odisha State Malaria Elimination Drive No drug interventions other Not Available completed NCT01857869
Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve Adults No drug interventions prevention 2 completed NCT01361269
Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria treatment 2 unknown_status NCT00913146
Can Treatment of Malaria be Restricted to Parasitologically Confirmed Malaria? No drug interventions Not Available Not Available completed NCT05343312
In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique treatment 4 active_not_recruiting NCT01669512
Adjuvanting Viral Vectored Malaria Vaccines With Matrix M prevention 1 completed NCT06294912
A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003) treatment 1 recruiting NCT02654912
Community-led Responses for Elimination: Controlled Trial of Reactive Case Detection Versus Reactive Drug Administration No drug interventions treatment 4 completed NCT06257810
Impact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and Antibiotic Use in West Africa No drug interventions diagnostic 4 completed NCT04660110
Household-level Impact of IPT of Malaria in Schoolchildren prevention 3 unknown_status NCT02646410
Optimization of Seasonal Malaria Chemoprevention (SMC) Delivery No drug interventions prevention Not Available unknown_status NCT05385510
Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV prevention 1 active_not_recruiting NCT00368810
Study of Factors Involved in Resistance to Severe Malaria No drug interventions Not Available Not Available completed NCT00190281
Contrast-Enhanced US of Spleen, Liver and Kidney No drug interventions Not Available Not Available unknown_status NCT00853281
A Cluster Randomized Trial to Evaluate Long Lasting Insecticidal Hammocks to Prevent Forest Malaria in Vietnam No drug interventions prevention Not Available completed NCT03510481
Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in Mali prevention 1 completed NCT01322581
A Longitudinal Systems Biological Analysis of Naturally Acquired Malaria Immunity in Mali No drug interventions Not Available Not Available completed NCT02509481
Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study treatment 2 / 3 completed NCT02453581
Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Volunteers treatment 1 completed NCT01434381
Initial Study of Malaria Vaccine Pfs25-EPA/Alhydrogel(Registered Trademark) No drug interventions prevention 1 completed NCT02640495
Artemisinin Resistance In Malaria Treated With IV Artesunate Not Available Not Available withdrawn NCT03855995
A Study to Evaluate the Safety, Effectiveness and Impact of the GlaxoSmithKline Biologicals' Malaria Vaccine- RTS, S/AS01E in Young Children in Sub-Saharan Africa No drug interventions Not Available Not Available recruiting NCT01392014
Dihydroartemisinin-piperaquine and Primaquine for Uncomplicated Plasmodium Falciparum Cases prevention 4 completed NCT03810014
Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1 No drug interventions health_services_research Not Available completed NCT01003314
A Study of the Safety and Effectiveness of Two New Malaria Vaccines No drug interventions prevention 1 / 2 completed NCT01130155
IMPACT2: Monitoring Interventions to Improve Artemisinin-based Combination Therapy (ACT) Access and Targeting No drug interventions Not Available Not Available unknown_status NCT04105855
Malaria Prevalence Around Maferinyah, Guinea No drug interventions Not Available Not Available completed NCT04800055
Attractive Targeted Sugar Bait Phase III Trial in Zambia No drug interventions prevention Not Available active_not_recruiting NCT01555255
Malaria Rapid Diagnostic Tests (RDTs) in Pregnancy: Detection of Placental Malaria No drug interventions Not Available Not Available unknown_status NCT00623155
Seasonal Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine in Children in Mali prevention Not Available completed NCT00850655
Genetic Association Mapping of Malaria Resistance in Anopheles Gambiae No drug interventions Not Available Not Available completed NCT00164255
Efficacy of Combination Therapy for Prevention of Effects of Malaria During Pregnancy prevention 4 completed NCT03934450
Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regimen basic_science 1 completed NCT01403350
Cluster Randomised Trial of Malaria RDTs Used by CHWs in Afghanistan No drug interventions diagnostic 4 completed NCT02859350
Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea. prevention 1 completed NCT03952650
Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa... other 1 / 2 completed NCT02149550
Controlled Human Malaria Infection After Bites From Mosquitoes Infected With Two Novel P. Falciparum Strains No drug interventions basic_science Not Available completed NCT00386750
Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function treatment 4 terminated NCT01814423
Pharmacokinetic Study of Multi-dose Chloroquine treatment 4 completed NCT02052323
Harmonized AS/MQ Efficacy Study - Thailand treatment 4 completed NCT00121823
Malaria Infection Diagnosed by Polymerase Chain Reaction (PCR) as a Means of Evaluating Pre-erythrocytic Candidate Malaria Vaccines No drug interventions prevention 1 / 2 completed NCT01753323
Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection treatment 2 completed NCT04618523
Safety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo treatment 4 completed NCT00331708
Artesunate Plus Sulfadoxine-pyrimethamine Pharmacokinetics, Efficacy, Gametocytes Carriage and Birth Outcomes in Pregnant Women With Malaria treatment Not Available terminated NCT00495508
Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy treatment 4 completed NCT02094508
Impact of TMP-SMX Prophylaxis on Malaria Infection and Immunity in Children in Uganda No drug interventions Not Available Not Available completed NCT01704508
Improving Anti-malarial Treatment Options in Guinea-Bissau - Part A treatment 4 completed NCT01464138
Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in Children treatment 2 completed NCT00873938
Compliance to Artesunate-Amodiaquine Therapy for Uncomplicated Malaria in Rural Ghana No drug interventions Not Available Not Available completed NCT02698774
Low Resource Diagnostics Development Cohort - VZNIGHT No drug interventions Not Available Not Available active_not_recruiting NCT02575755
A Safety, Tolerability, Pharmacokinetic and Efficacy Study of Azithromycin Plus Piperaquine as Presumptive Treatment in Pregnant PNG Women prevention 4 unknown_status