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Displaying results 761 - 770 of 10000 in total
  1. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0001684
    TargetHumans

    Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798). Binds copper ions (By similarity)

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  2. Target

    Cytosol aminopeptidase

    go.drugbank.com/bio_entities/BE0003882
    TargetHumans

    For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. … Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status

    Synonyms: Peptidase S, Cysteinylglycine-S-conjugate dipeptidase
  3. Target

    Complement C1s subcomponent

    go.drugbank.com/bio_entities/BE0001529
    TargetEnzymeHumans

    Component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the ...

    Synonyms: Complement component 1 subcomponent s
  4. Indication

    Adrenal Cushing Syndrome

    go.drugbank.com/conditions/DBCOND0148294
    Drugs: Mitotane
    Synonyms: Cushing s Syndrome
  5. Target

    Glyceraldehyde-3-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0000542
    TargetHumans

    Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)

    Synonyms: Peptidyl-cysteine S-nitrosylase GAPDH
  6. Drug

    Cholecalciferol

    go.drugbank.com/drugs/DB00169
    ApprovedInvestigationalNutraceutical

    Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation

    Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-D
  7. Indication

    Fabry's Disease

    go.drugbank.com/conditions/DBCOND0028300
    Drugs: Agalsidase alfa · Agalsidase beta · Migalastat · Pegunigalsidase alfa
    Synonyms: Fabry´s Disease
  8. Indication

    Menière's Disease

    go.drugbank.com/conditions/DBCOND0066647
    Drugs: Betahistine · Dimenhydrinate · Diphenidol · Levosulpiride · Pyridoxine · Streptomycin +1 more
    Synonyms: Meniere s Disease
  9. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0009225
    TargetPlasmodium falciparum (isolate 3D7)

    Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  10. Target

    Maleylacetoacetate isomerase

    go.drugbank.com/bio_entities/BE0000819
    TargetEnzymeHumans

    Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Also has low glutathione peroxidase activity with T-butyl and...

    Synonyms: Glutathione S-transferase zeta 1