Search

Displaying results 781 - 790 of 10000 in total
  1. Drug

    Carbidopa

    go.drugbank.com/drugs/DB00190
    ApprovedInvestigational

    An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea. … therapy developed by Mayne Pharma in 1992.

    Mixtures: ISICOM 100MG/25MG, ISICOM 100MG/25MGProducts: Carbidopa and Levodopa, Carbidopa and levodopa
  2. Pathway

    Glycine and Serine Metabolism

    smpdb.ca/view/SMP0000004
    Metabolic

    All of these compounds share common intermediates and almost all can be biosynthesized from one another. Serine and glycine are not essential amino acids and can be synthesized from several routes. … On the other hand, cysteine is a conditionally essential amino acid, meaning that it can be endogenously synthesized but insufficient quantities may be produced due to certain diseases or conditions.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  3. Pathway

    Taurine and Hypotaurine Metabolism

    smpdb.ca/view/SMP0000021
    Metabolic

    Moreover, this entire process can be catalyzed via bile acid and a special amino acid N-acetyltransferase. … This includes acids such as chenodeoxycholic acid and cholic acid, and in turn the formation of bile salts occurs.

    Drugs: Pyridoxal phosphate · Cysteine · Cysteamine · Iron · Taurine
  4. Pathway

    Pantothenate and CoA Biosynthesis

    smpdb.ca/view/SMP0000027
    Metabolic

    It is a precursor of coenzyme A, which is an essential part of many reactions in the body, specifically important in the production of compounds like cholesterol and different fatty acids. … Most of pantothenic acid is found in food as phosphopentetheine or coenzyme A. Pantothenic acid, pantetheine 4’-phosphate and pantetheine are all found in red blood cells.

    Drugs: Adenosine phosphate · Cysteine · ATP · Cysteamine · Calcium · Pantothenic acid +3 more
  5. Pathway

    Starch and Sucrose Metabolism

    smpdb.ca/view/SMP0000058
    Metabolic

    It’s formed primarily in liver and muscle tissues, but is also formed at secondary sites such as the central nervous system and the stomach. In both cases it exists as free granules in the cytosol. … Amylase enzymes secreted in saliva by the parotid gland and in the small intestine play an important role in initiating starch digestion.

    Drugs: Pyridoxal phosphate · NADH · ATP · Calcium · Magnesium cation · Uridine diphosphate glucose +4 more
  6. Pathway

    Spermidine and Spermine Biosynthesis

    smpdb.ca/view/SMP0000445
    Metabolic

    Spermidine and spermine are produced in many tissues, as they are involved in the regulation of genetic processes from DNA synthesis to cell migration, proliferation, differentiation and apoptosis. … The Spermidine and Spermine Biosynthesis pathway highlights the creation of these cruicial polyamines.

    Drugs: Pyridoxal phosphate · Ademetionine · Spermine · Ornithine · Methionine · ATP +6 more
  7. Drug

    Valsartan

    go.drugbank.com/drugs/DB00177
    ApprovedInvestigational

    Valsartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions. … ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.

    Mixtures: CARDIK - IN® 160/2.5, CARDIK - IN® 160/2.5Categories: Angiotensin II Antagonists and Diuretics, Angiotensin II Antagonists and Calcium Channel Blockers
  8. Drug

    Nelfinavir

    go.drugbank.com/drugs/DB00220
    ApprovedInvestigational

    Nelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. … Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.[L36485]

    Products: Viracept -250mg, Viracept -50mg
  9. Drug

    Insulin glargine

    go.drugbank.com/drugs/DB00047
    ApprovedInvestigational

    Insulin is an important treatment in the management of Type 1 Diabetes (T1D), which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able … Without an adequate supply of insulin to promote absorption of glucose from the bloodstream, blood sugar levels can climb to dangerously high levels and can result in symptoms such as fatigue, headache

    Mixtures: SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML, Soliqua SoloStar 100units/mL+50mcg/mL solution for injection in a pre-filled penCategories: Drugs Used in Diabetes, Alimentary Tract and Metabolism
  10. Drug

    Clofibrate

    go.drugbank.com/drugs/DB00636
    ApprovedWithdrawn

    A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)

    Products: Atromid-S Cap 500mg, Atromid S Cap 500mg