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Displaying results 71 - 80 of 87 in total
  1. Pathway

    Adenylosuccinate Lyase Deficiency

    smpdb.ca/view/SMP0125722
    Disease

    Adenylosuccinate Lyase Deficiency. (Adenylosuccinase Deficiency ; Adenylosuccinate monophosphate lyase deficiency) is a rare autosomal recessive disease caused by a mutation in the ADSL gene which codes for adenylosuccinate lyase. A defi...

    Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +24 more
  2. Pathway

    Gout or Kelley-Seegmiller Syndrome

    smpdb.ca/view/SMP0125723
    Disease

    Gout, also called Kelley-Seegmiller syndrome, is a condition that is hereditary and causes an excess in the production of uric acid in the body. It is caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase. W...

    Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +24 more
  3. Pathway

    Xanthinuria Type II

    smpdb.ca/view/SMP0125731
    Disease

    Xanthinuria Type II (Xanthine Dehydrogenase Deficiency) is a rare inborn error of metabolism (IEM) and autosomal recessive disorder and caused by a defective xanthine dehydrogenase. Xanthine dehydrogenase catalyzes the conversion of hypo...

    Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +24 more
  4. Pathway

    Thioguanine Action Pathway (old)

    smpdb.ca/view/SMP0000430
    Drug action

    Thioguanine is a purine antimetabolite prodrug closely related to mercaptopurine and similarly inhibits purine metabolism. The thioguanine pathway is shown as a part of the mercaptopurine pathway. Thioguanine exerts cytotoxic effects via...

    Drugs: Tetrahydrofolic acid · Ademetionine · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid +27 more
  5. Pathway

    Azathioprine Action Pathway

    smpdb.ca/view/SMP0000427
    Drug action

    Azathioprine is a purine antimetabolite prodrug that exerts cytotoxic effects via three mechanisms: via incorporation of thiodeoxyguanosine triphosphate into DNA and thioguanosine triphosphate into RNA, inhibition of de novo synthesis of...

    Drugs: Tetrahydrofolic acid · Ademetionine · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid +27 more
  6. Pathway

    Mercaptopurine Action Pathway

    smpdb.ca/view/SMP0000428
    Drug action

    Mercaptopurine is a purine antimetabolite prodrug that exerts cytotoxic effects via three mechanisms: via incorporation of thiodeoxyguanosine triphosphate into DNA and thioguanosine triphosphate into RNA, inhibition of de novo synthesis ...

    Drugs: Tetrahydrofolic acid · Ademetionine · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid +26 more
  7. Indication

    Infections

    go.drugbank.com/conditions/DBCOND0024541
    Drugs: Acetic acid · Ampicillin · Bacitracin · Benzamidine · Calcium hypochlorite · Chlorhexidine +18 more
  8. Pathway

    Disulfiram Action Pathway

    smpdb.ca/view/SMP0000429
    Drug action

    Disulfiram is a drug used in the treatment of cocaine addiction and chronic alcoholism. With regards to cocaine addiction, cocaine inhibits dopamine reuptake by blocking dopamine transporter 1 (DAT1). This increases dopamine concentratio...

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Adenosine phosphate · Tyrosine +27 more
  9. Indication

    Diaper Rash

    go.drugbank.com/conditions/DBCOND0005733
    Drugs: Balsam of Peru · Benzalkonium · Cetrimonium · Dexpanthenol · Dimethicone 410 · Hydrocortisone acetate +8 more
  10. Indication

    Gingivitis

    go.drugbank.com/conditions/DBCOND0010261
    Drugs: Amylmetacresol · Benzalkonium · Benzamidine · Benzocaine · Benzydamine · Cetylpyridinium +9 more