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Displaying results 81 - 90 of 220 in total
  1. Pathway

    Dezocine Action Pathway

    smpdb.ca/view/SMP0000676
    Drug action

    The binding of dezocine will eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter. … Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.

    Drugs: ATP · Norepinephrine · Dopamine · Dezocine · Potassium cation · Calcium
    Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter
  2. Pathway

    Levallorphan Action Pathway

    smpdb.ca/view/SMP0000683
    Drug action

    Levallorphan (also known as Lorfan and Naloxifan) is a type of medication that can be used for treating drug overdoses and respirotry depression. … Levallorphan can bind to mu-type opioid receptor and kappa-type opioid receptor on neuron of central nerves system (CNS).

    Drugs: ATP · Norepinephrine · Levallorphan · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter
  3. Pathway

    Buprenorphine Action Pathway

    smpdb.ca/view/SMP0000684
    Drug action

    and symptoms of withdrawal. … Buprenorphine, trade name subutex, suboxone, zubsolv and bunavail, is a partial agonist of mu-opioid receptors and a kappa-opioid receptor antagonist and is prescribed for opioid addiction to prevent cravings

    Drugs: ATP · Norepinephrine · Buprenorphine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter
  4. Pathway

    Naltrexone Action Pathway

    smpdb.ca/view/SMP0000687
    Drug action

    Naltrexone (also known as ReVia and Vivitrol) is a competitive antagonist of mu-type opioid receptor in the central nervous system (CNS).

    Drugs: ATP · Norepinephrine · Naltrexone · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter
  5. Pathway

    Dihydromorphine Action Pathway

    smpdb.ca/view/SMP0000689
    Drug action

    Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein. … The binding of dihydromorphine acetate will eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter.

    Drugs: ATP · Norepinephrine · Dopamine · Potassium cation · Calcium · Dihydromorphine
    Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter
  6. Pathway

    Ketobemidone Action Pathway

    smpdb.ca/view/SMP0000690
    Drug action

    Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein. … The binding of ketobemidone acetate will eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter.

    Drugs: ATP · Norepinephrine · Dopamine · Potassium cation · Calcium · Ketobemidone
    Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter
  7. Pathway

    Nalbuphine Action Pathway

    smpdb.ca/view/SMP0000691
    Drug action

    Nalbuphine (also known as Rubuphine and Nubain) is a competitive antagonist of mu-type and kappa-type opioid receptor in the central nervous system (CNS).

    Drugs: ATP · Norepinephrine · Nalbuphine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter
  8. Indication

    Hypoglycemia

    go.drugbank.com/conditions/DBCOND0020360
    Drugs: D-glucose · Dextrose, unspecified form
  9. Indication

    Hypokalemia

    go.drugbank.com/conditions/DBCOND0003942
    Drugs: Amiloride · Potassium · Potassium acetate · Potassium aspartate · Potassium bicarbonate · Potassium chloride +2 more
  10. Pathway

    Methadone Action Pathway

    smpdb.ca/view/SMP0000408
    Drug action

    Methadone further acts as an antagonist at the NMDA receptor, reducting calcium influx and neuronal excitability. … G(i) also activates potassium channels and inactivates calcium channels causing the neuron to hyperpolarize.

    Drugs: NADH · ATP · Methadone · Norepinephrine · Dopamine · Potassium cation +3 more
    Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter