Search
Peptidyl-prolyl cis-trans isomerase B
go.drugbank.com/bio_entities/BE0002332TargetHumansPeptidyl-prolyl cis-trans isomerase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding
Synonyms: S-cyclophilinPurine nucleoside phosphorylase
go.drugbank.com/bio_entities/BE0003172TargetPlasmodium falciparum (isolate 3D7)Also catalyzes the phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine; MTI is produced by adenosine deaminase (ADA)-mediated breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product
Synonyms: S-methyl-5'-thioinosine phosphorylaseDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approved[A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730] … Doxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967.
Synonyms: 5-hydroxy-α-6-deoxytetracycline, 6-alpha-deoxy-5-oxytetracyclineCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsHodgkin's Lymphoma
go.drugbank.com/conditions/DBCOND0030382Drugs: Bleomycin · Chlorambucil · Cyclophosphamide · Dacarbazine · Doxorubicin · Gemcitabine +5 moreSynonyms: Hodgkin´s Lymphomas, Hodgkin´s LymphomaGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigationalAs Alzheimer's disease is a progressive neurodegenerative disorder, galantamine is not known to alter the course of the underlying dementing process. … [L13571] It is therefore not considered to be a disease-modifying drug.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: REMINYL ®ER CAPSULAS DE 8 MG, REMINYL® SOLUCION ORAL DE 4 MG/MLLeukotriene C4 synthase
go.drugbank.com/bio_entities/BE0001117TargetHumansCan also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator
Synonyms: Glutathione S-transferase LTC4Thymol
go.drugbank.com/drugs/DB02513ApprovedInvestigationalA phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. … It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Synonyms: 5-Methyl-2-(1-Methylethyl)Phenol, 2-isopropyl-5-methylphenolMixtures: Aurora Blue Mint, Aurora Fresh BurstCap-specific mRNA (nucleoside-2'-O-)-methyltransferase
go.drugbank.com/bio_entities/BE0001402TargetVACVDisplays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the...
Synonyms: PAP-SUroporphyrinogen-III C-methyltransferase
go.drugbank.com/bio_entities/BE0002528TargetPseudomonas denitrificansCatalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1. It is a step in the biosynthesis of both cobalamin (vitamin B...
Synonyms: S-adenosyl-L-methionine:uroporphyrinogen III methyltransferaseLactoylglutathione lyase
go.drugbank.com/bio_entities/BE0000962TargetEnzymeHumansCatalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294).
Synonyms: S-D-lactoylglutathione methylglyoxal lyase