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Propyl alcohol Drug Metabolism
smpdb.ca/view/SMP0130505MetabolicPropyl alcohol passes through the liver and is then excreted from the body mainly through the kidney. … Propyl alcohol is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Propyl alcoholDisulfiram Aldehyde Dehydrogenase Inhibitor Action Pathway
smpdb.ca/view/SMP0122693Drug actionThe unpleasant symptoms (vasodilation, flushing, hypotension, respiratory problems) are meant to deter the patient away from wanting to use alcohol as disulfiram and alcohol together lead to the unwanted … Disulfiram is a carbamate derivative used to treat chronic alcoholism.
Enzymes: Alcohol dehydrogenase 1BCelecoxib metabolism Pathway
smpdb.ca/view/SMP0000644MetabolicCelecoxib, a non-steroidal anti-inflammatory drug (NSAID), is a selective inhibitor of cyclooxygenase-2 (COX-2), also known as prostaglandin G/H synthase 2. Like other NSAIDs, celecoxib exerts its effects by inhibiting the synthesis of p...
Enzymes: Alcohol dehydrogenase 1B, Alcohol dehydrogenase 1AFelbamate Metabolism Pathway
smpdb.ca/view/SMP0000633Drug metabolismThe latter is further converted by the alcohol dehydrogenase 1A to 5-phenyl-1,3-oxazinane-2,4-dione, which is subsequently transformed to 3-carbamoyl-2-phenylpropionic acid. … This metabolite is then converted to 3-carbamoyl-2phenylpropionaldehyde via alchol dehydrogenase 1A, which in turn can be transformed into three possible metabolites: atropaldehyde, 3-carbamoyl-2-phenylpropionic
Enzymes: Alcohol dehydrogenase 1AFenofibrate Metabolism Pathway
smpdb.ca/view/SMP0125319MetabolicFenofibrate is a peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. Fenofibrate is a fibrate th...
Ethanol Degradation
smpdb.ca/view/SMP0000449MetabolicIn the alcohol dehydrogenase mediated ethanol degradation pathway (I), cytoplasmic alcohol dehydrogenase produces the acetaldehyde from the ethanol. … The alcohol dehydrogenase mediated ethanol degradation pathway (I) is the predominant mechanism of catabolism under conditions of acute alcohol consumption.
Enzymes: Alcohol dehydrogenase 1BSulfite Oxidase Deficiency
smpdb.ca/view/SMP0000532DiseaseSulfite oxidase deficiency (SOD) is a disorder, an autosomal recessive disease. In classic SOD, it is usually identified a few days after the birth of an affected individual, and is recognizable through characteristic dysmorphic features...
Disulfiram Action Pathway
smpdb.ca/view/SMP0000429Drug actionTherefore, disulfiram is not suggested to take while patient consuming alcohol. … Disulfiram is a drug used in the treatment of cocaine addiction and chronic alcoholism.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Adenosine phosphate · Tyrosine +27 moreEnzymes: Alcohol dehydrogenase 1B, Alcohol dehydrogenase 1ASulfate/Sulfite Metabolism
smpdb.ca/view/SMP0000041MetabolicThis pathway illustrates the conversion of sulfite to sulfate (via sulfate oxidase) and subsequent generation of adenylylsulfate (APS) via 3'-phosphoadenosine 5'-phosphosulfate synthase 2. APS is converted to phosphoadenylyl-sulfate (PAP...
Sulfite Oxidase Deficiency
smpdb.ca/view/SMP0125709DiseaseSulfite oxidase deficiency (SOD) is a disorder, an autosomal recessive disease. In classic SOD, it is usually identified a few days after the birth of an affected individual, and is recognizable through characteristic dysmorphic features...