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Displaying results 1 - 10 of 35 in total
  1. Drug

    Benazepril

    go.drugbank.com/drugs/DB00542
    ApprovedInvestigational

    Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836]. … Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837].

    Synonyms: Benazepril, BenazeprilumSalts: Benazepril hydrochloride
  2. Pathway

    Benazepril Action Pathway

    smpdb.ca/view/SMP0000145
    Drug action

    Benazepril is a prodrug which, following oral administration, undergoes biotransformation in vivo into its active form benazeprilat via cleavage of its ester group by the liver. … Benazepril (trade name: Lotensin) belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension).

    Drugs: Benazepril · Potassium cation · Zinc
  3. Pathway

    Benazepril Metabolism Pathway

    smpdb.ca/view/SMP0000591
    Drug metabolism

    Benazepril is a prodrug which, following oral administration, undergoes biotransformation in vivo into its active form benazeprilat via cleavage of its ester group by the liver. … Benazepril (trade name: Lotensin) belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension).

    Drugs: Benazepril · Zinc
  4. Pathway

    Benazepril ACE inhibitor Action Pathway

    smpdb.ca/view/SMP0122803
    Drug action

    Benazepril is converted into benazeprilat through the liver after being ingested which travels in the blood to inhibit ACE which is from the lungs. … Benazepril is angiotensin converting enzyme (ACE) inhibitor for the conversion of angiotensin I into angiotensin II.

    Drugs: Glutamic acid · Benazepril · Zinc
  5. Drug

    Hydrochlorothiazide

    go.drugbank.com/drugs/DB00999
    ApprovedInvestigationalVet approved

    Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension. Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combinati...

    Mixtures: Benazepril Hydrochloride and Hydrochlorothiazide, Benazepril Hydrochloride and HydrochlorothiazideProducts: BENAZEPRIL IDROCLOROTIAZIDE EG, HYDROCHLORZIDE-50 TABLET
  6. Drug

    Amlodipine

    go.drugbank.com/drugs/DB00381
    ApprovedInvestigational

    Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyri...

    Mixtures: Amlodipine Besylate and Benazepril Hydrochloride, Amlodipine and Benazepril HydrochlorideCategories: benazepril and amlodipine
  7. Indication

    Non-diabetic Nephropathy

    go.drugbank.com/conditions/DBCOND0051159
    Drugs: Benazepril
  8. Indication

    Diabetic Nephropathy

    go.drugbank.com/conditions/DBCOND0028920
    Drugs: Benazepril · Candesartan cilexetil · Captopril · Enalapril · Enalaprilat · Eprosartan +9 more
  9. Indication

    Heart Failure

    go.drugbank.com/conditions/DBCOND0027920
    Drugs: Alteplase · Atenolol · Benazepril · Bisoprolol · Captopril · Enalaprilat +10 more
  10. Indication

    Hypertension

    go.drugbank.com/conditions/DBCOND0020037
    Drugs: Acebutolol · Aliskiren · Amiloride · Amlodipine · Ammonium chloride · Aprocitentan +78 more