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Urea C-13 Drug Metabolism
smpdb.ca/view/SMP0130503MetabolicUrea C-13 passes through the liver and is then excreted from the body mainly through the kidney. … Urea C-13 is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Urea C-13Urea C-14 Drug Metabolism
smpdb.ca/view/SMP0130502MetabolicUrea C-14 passes through the liver and is then excreted from the body mainly through the kidney. … Urea C-14 is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Urea C-14Fish oil Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway
smpdb.ca/view/SMP0126563Drug actionFish oil is made of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). … Fish oil is administered as an oral capsule or tablet, it can also be found as a parenteral emulsion when oral or enteral nutrition is not possible, insufficient, or contraindicated for different reasons
Urea Cycle
smpdb.ca/view/SMP0000059MetabolicArginine cleaves and creates urea and ornithine, and the reactions that follow see urea residue build up on ornithine, which recreates arginine and keeps the cycle going. … Urea, also known as carbamide, is a waste product made by a large variety of living organisms and is the main component of urine.
Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 moreProtein C Action Pathway
smpdb.ca/view/SMP0126878Drug actionProtein C is also known under brand names such as Balfaxar, Beriplex, Ceprotin, Kcentra and Octaplex used to treat purpura fulminans and or coumarin-induced skin necrosis. … Activated Protein C acts as a serine protease that acts by inactivating coagulation factors V and VIII, decreasing clot formation.
Enzymes: Protein CCastor Oil Action Pathway
smpdb.ca/view/SMP0174887Drug actionCastor Oil may also promote ulcer healing by increasing mucus and bicarbonate secretion and thickening the mucosal bilayer so the mucosa can generate new cells. … Castor Oil stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Castor Oil activates prostaglandin EP3 receptors in parietal cells.
Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 morePhospholipase C Signaling Pathway
smpdb.ca/view/SMP0063783SignalingIt functions to activate inositol lipid signalling pathways causing the hydrolysis of PIP2 by PLC to IP3 and diacylglycerol to activate protein kinase C. … PIP3 is an important regulator of AKT signaling and downstream pathways.
Drugs: CalciumEnzymes: Protein kinase C alpha typeCholine C-11 Drug Metabolism
smpdb.ca/view/SMP0130934MetabolicCholine C-11 passes through the liver and is then excreted from the body mainly through the kidney. … Choline C-11 is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Choline C-11Glutaminolysis and Cancer
smpdb.ca/view/SMP0002298DiseaseThe transportation of glutamine in and out regulates mTOR activation to coordinate cell growth and proliferation. … Once it reaches malic acid, it is transported outside the mitochondria and transformed into pyruvic acid and lactate.
Drugs: Pyridoxal phosphate · Pyruvic acid · Biotin · Aspartic acid · L-Glutamine · Succinic acid +9 moreEnzymes: C-Myc-binding proteinNicotinate and Nicotinamide Metabolism
smpdb.ca/view/SMP0000048MetabolicNicotinate (niacin) and nicotinamide - more commonly known as vitamin B3 - are precursors of the coenzymes nicotinamide-adenine dinucleotide (NAD+) and nicotinamide-adenine dinucleotide phosphate (NADP … The precursors are fed into the NAD+ biosynthetic pathwaythrough adenylation and phosphoribosylation reactions.