Displaying drugs 3451 - 3475 of 11857 in total
Dasabuvir
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Description: … Dasabuvir is a non-nucleoside NS5B inhibitor which binds to the palm domain of NS5B and induces a conformational ... Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 …
Thallous chloride
Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation of thallium from its ores. It is created from the treatment of thallium(I) sulfate with hydrochloric acid. This solid crystallizes in the caesium chloride motif. It is used as a diagnostic radiopharmaceutical. It is used...
Approved
Matched Description: … It is used as a diagnostic radiopharmaceutical. ... Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation …
Stannous chloride
Stannous chloride is used as a source of tin in radiopharmaceutical kits. Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities . These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis...
Approved
Matched Description: … Stannous chloride is used as a source of tin in radiopharmaceutical kits. ... Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing …
Serdexmethylphenidate
Attention Deficit Hyperactivity Disorder (ADHD) is an early-onset neurodevelopmental disorder that often extends into adulthood and is characterized by developmentally inappropriate and impaired attention, impulsivity, and motor hyperactivity.[A230698, A230703] The underlying cause of ADHD is unclear but likely involves dysfunction in dopaminergic and noradrenergic neurotransmission, as evidenced by the clear...
Approved
Matched Description: … [A230698, A230708] Serdexmethylphenidate is a prodrug of the CNS stimulant [dexmethylphenidate], a common ... L32323]
Serdexmethylphenidate was granted FDA approval on March 2, 2021, and is currently marketed as a …
Berberine
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Approved
Investigational
Human cytomegalovirus immune globulin
Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label].
Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Description: … Cytomegalovirus (CMV) may lead to a wide spectrum of infection in immunocompetent hosts. ... Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to ... CMV infection can lead to a high fever and severe organ-specific damage with significant morbidity and …
Adenosine phosphate
Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Description: … was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a …
Levothyroxine
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Description: … Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the ... L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a ... [F4636,A35722]
In response to Thyroid Stimulating Hormone (TSH) release by the pituitary gland, a …
Matched Categories: … UGT1A1 Substrates with a Narrow Therapeutic Index …
Matched Categories: … UGT1A1 Substrates with a Narrow Therapeutic Index …
Ozanimod
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada...
Approved
Investigational
Matched Description: … Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple ... decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard ... [A189336]
In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher …
Diazoxide
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Description: … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels ... In September 2015, the FDA issued a safety alert regarding post-marketing reports of pulmonary hypertension …
St. John's Wort
Approved
Investigational
Nutraceutical
Naloxone
Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Description: … as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. ... effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a ... [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an …
Galantamine
Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantamine...
Approved
Matched Description: … [L13571] It is therefore not considered to be a disease-modifying drug. ... Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase ... [A1018] First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted …
Poractant alfa
Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alfa is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids)...
Approved
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... Poractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. …
Iocetamic acid
Iocetamic acid is a diagnostic aid (radiopaque medium)
Approved
Matched Description: … Iocetamic acid is a diagnostic aid (radiopaque medium) …
Aluminum oxide
Aluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in food contact substances by the FDA.
Approved
Matched Description: … Aluminum oxide has a chemical formula Al2O3. …
Betulinic Acid
Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
Approved
Investigational
Etidronic acid
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification …
Salix alba bark
Salix alba bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Salix alba bark is a plant/plant extract used in some OTC (over-the-counter) products. …
Gadopiclenol
Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Description: … Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. ... 2006, the use of GBCAs was associated with the development of nephrogenic systemic fibrosis (NSF), a ... [A254002] Gadopiclenol has high kinetic stability and a high r1 relaxivity, allowing it to be used at …
Tasonermin
Tasonermin is recombinant soluble form tumor necrosis factor α produced via Escherichia coli cell culture. It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft...
Approved
Apricot kernel oil
Apricot kernel oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Apricot kernel oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Arnica montana flower
Arnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Arnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. …
Displaying drugs 3451 - 3475 of 11857 in total