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Displaying drugs 451 - 475 of 15298 in total

Guanadrel

Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
Approved
Matched Iupac: … N''-({1,4-dioxaspiro[4.5]decan-2-yl}methyl)guanidine …
Matched Salts cas: … 22195-34-2 …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may ... Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … Ni-C-E-LE Plus ... FLAVETTES DAILY PLUS TABLET F/C ... For-2 …
Matched Products: … XENETIX 350-50ML SOLN FOR INTRAVASCULAR INJ ... XENETIX 300-50ML SOLN FOR INTRAVASCULAR INJ ... XENETIX 350-100ML SOLN FOR INTRAVASCULAR INJ …

Emicizumab

Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation ... The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity …
Matched Products: … HEMLIBRA 30MG/ML SOLUTION FOR INJECTION ... HEMLIBRA 150MG/ML SOLUTION FOR INJECTION ... HEMLIBRA SOLUTION FOR INJECTION 30MG/ML …

Bisphenol A diglycidyl ether

Approved
Experimental
Matched Synonyms: … Diglycidyl bisphenol A ether …
Matched Name: … Bisphenol A diglycidyl ether …
Matched Iupac: … 2-{[4-(2-{4-[(oxiran-2-yl)methoxy]phenyl}propan-2-yl)phenoxy]methyl}oxirane …

Lutropin alfa

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 ... Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... It is a heterodimeric glycoprotein made up of monomeric units. …
Matched Mixtures name: … PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 3 ADET ... Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Products: … LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …

Fentanyl

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose ... Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin. …
Matched Products: … DUROGESIC SMAT 12 A 2.1MG ... DUROGESIC SMAT 25 A 4.2MG ... DUROGESIC SMAT 50 A 8.4MG …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. ... XLH is a serious disease which affects about 3,000 children and 12,000 adults in the United States. ... throughout a patient’s life [L2346]. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … CRYSVITA® SOLUTION FOR INJECTION 10 MG/ML ... CRYSVITA® SOLUTION FOR INJECTION 30 MG/ML ... CRYSVITA® SOLUTION FOR INJECTION 20 MG/ML …

Haloperidol

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Synonyms: … 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine …
Matched Description: … for the treatment of intractable hiccups as it is a potent antiemetic. ... [A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain ... or histaminergic receptors, resulting in a higher incidence of side effects such as sedation, weight …
Matched Products: … MYUNG IN HALOPERIDOL TABLET 1.5 mg ... MYUNG IN HALOPERIDOL INJECTION 5 mg/ml ... Haldol Decanoat 150 mg/3 ml Injektionslösung …

Ceftriaxone

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(2-methyl-5,6-dioxo-1,2,5,6 ... -tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Description: … , its relatively safe adverse effect profile, and its long half-life which allows for the convenience ... Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the …
Matched Mixtures name: … CEF-3 INJECTION IM (1G) ... CEF-3 INJECTION IM (1G) ... CEF-3 INJECTION IM (250MG) …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CEF-3 FOR IV INJECTION 500 mg/5 ml ... CEFTRIAXONA 1000 MG POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE. ... CEFIN FOR INJECTION 2 g/vial …

Chorionic Gonadotropin (Human)

Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Description: … luteum to continuously secrete the hormone progesterone during the first trimester, which is required for ... As a drug product, chorionic gonadotropin is a highly purified pyrogen-free preparation obtained from ... In males, HCG also stimulates the production of gonadal steroid hormones by stimulating the interstitial …
Matched Products: … E. - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung ... CHORAGON 5000 IU IM ENJEKSIYONLUK ÇÖZELTI IÇIN TOZ VE ÇÖZÜCÜ AMPUL, 3 ADET ... PREGNYL 1500 IU IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 3 ADET …

Denosumab

Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … fracture receiving adjuvant aromatase inhibitor therapy for breast cancer in September 2011 and in men ... with osteoporosis at high risk for fracture in September 2012. ... [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … XGEVA 120mg Solution for Injection ... XGEVA Solution for Injection 120 mg/vial ... Prolia Solution for Injection 60mg Pre-filled Syringe …

Oxytocin

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … Vincent du Vigneaud; he was later recognized with a Nobel prize for his work. ... [A229013] Oxytocin also serves a role in metabolic homeostasis and cardiovascular regulation. ... [A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named …
Matched Products: … Oxytocin-Richter solution for injection 10 I.U / 1 ml ... ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 3 ADET …

Cashew

Cashew allergenic extract is used in allergenic testing.
Approved
Matched Description: … Cashew allergenic extract is used in allergenic testing. …

Trimipramine

Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Approved
Matched Synonyms: … 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine ... 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine ... 5-(γ-dimethylamino-β-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}-2-methylpropyl)dimethylamine …
Matched Salts cas: … 25332-13-2 …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Antidepressive Agents Indicated for Depression ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …

Passiflora incarnata flower

Approved
Experimental

Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Iupac: … )-1-acetyl-5,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … , and is also used in palliative care for endometrial and renal carcinoma. ... for improved pharmacokinetic properties. ... Medroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism …
Matched Mixtures name: … DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Products: … DEPONEO 3 …

Iobenguane

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Synonyms: … 3-iodobenzylguanidine ... ((3-iodophenyl)methyl)guanidine …
Matched Iupac: … N''-[(3-iodophenyl)methyl]guanidine …
Matched Description: … The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that ... Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008. ... Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. …
Matched Salts cas: … 149210-33-3 …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Propiolactone

Propiolactone is a lactone compound with a four-membered ring. It is a colorless liquid with a pungent slightly sweet odor. Propiolactone is a disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and enzymes. It has been used against bacteria, fungi, and virus. It is currently...
Approved
Withdrawn
Matched Synonyms: … 3-propanolide …
Matched Iupac: … oxetan-2-one …
Matched Description: … [A32144] It is currently FDA approved for its use as an indirect additive used in food contact substances ... Propiolactone is a disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, ... Propiolactone was first commercially available in the United States in 1958.[A32144] …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Agalsidase alfa

Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Synonyms: … alpha-galactosidase A ... Recombinant alpha-galactosidase A …
Matched Description: … a contamination event in 2009. ... [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413] ... While patients generally do not experience a clinically significant difference in outcomes between the …
Matched Products: … REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML …

Varicella zoster vaccine (recombinant)

Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Synonyms: … gE recombinant Varicella zoster virus (VZV) glycoprotein E ... Recombinant Varicella zoster virus (VZV) glycoprotein E ... gE: Recombinant Varicella Zoster Virus (VZV) glycoprotein E …
Matched Description: … The main immunological component of Shingrix vaccine is glycoprotein E (gE), a protein found on the surface ... for preventing varicella zoster infection in people aged 50 years and older, replacing Zostavax as first ... Risk factors for developing shingles include old age, with rates increasing substantially in person's …
Matched Products: … SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5ML …

Tetrofosmin

Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Approved
Matched Iupac: … 6,9-bis(2-ethoxyethyl)-3,12-dioxa-6,9-diphosphatetradecane …
Matched Description: … It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. ... Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788] …
Matched Products: … MYOVIEW POWDER FOR INJECTION ... MYOVIEW FOR INJECTION 0.23 mg/vial …

Fondaparinux

Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Iupac: … -3-(sulfoamino)-6-[(sulfooxy)methyl]oxan-2-yl]oxy}-3,4-dihydroxyoxan-2-yl]oxy}-3-(sulfoamino)-4-(sulfooxy ... )-2-[(sulfooxy)methyl]oxan-3-yl]oxy}-5-(sulfooxy)oxane-2-carboxylic acid ... (2R,3S,4S,5R,6R)-3-{[(2R,3R,4R,5R,6R)-5-{[(2R,3R,4R,5S,6S)-6-carboxy-5-{[(2R,3R,4R,5S,6R)-4,5-dihydroxy ... )-6-[(sulfooxy)methyl]oxan-2-yl]oxy}-4-hydroxy-6-{[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfoamino …
Matched Description: … The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural ... a O-methyl group at the reducing end of the molecule. ... Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and …
Matched Products: … COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 2 ADET ... ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 2 ADET ... ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 2 ADET …

Ibandronate

Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Iupac: … {1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl}phosphonic acid …
Matched Description: … [L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss ... in dogs. ... Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic …
Matched Mixtures name: … IBAMIN D3 150 MG/2800 IU SAŞE ,3 SAŞE ... IBAMIN D3 150 MG/2800 IU FİLM KAPLI TABLET, 3 ADET …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … OSTIVEA 3mg/3ml Solution for IV Injection in Pre-filled Syringe ... ASCENDRA 3MG DUO CA 1 + 90 ... BONDRONAT 2 MG/2 ML AMPUL, 5 ADET …

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Iupac: … (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl ... ]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14 …
Matched Description: … In March 2020, a small study was funded by the French government to investigate the treatment of COVID ... It was initially approved by the FDA in 1991 [A174175]. ... The results were positive, all patients taking the combination were virologically cured within 6 days …
Matched Categories: … Medications that reduce magnesium levels ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … GLED' C ZIT ... ZITROTEK FILM KAPLI TABLET, 2 ADET ... AZİTROTEK 500 MG FİLM TABLET, 2 TABLET …

Hydralazine

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … [A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development ... Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability ... [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment …
Matched Categories: … Medications that reduce magnesium levels ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … APRESOLINE FOR INJECTION 20 mg/ampoule …
Displaying drugs 451 - 475 of 15298 in total