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Displaying drugs 451 - 475 of 11603 in total
Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Description: … Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. ... [A228323] Milrinone is a second-generation bipyridine phosphodiesterase (PDE) inhibitor created through ... [A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Description: … Sulfathiazole is a short-acting sulfa drug. ... It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. …
Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … powder for oral suspension that acts as a highly selective potassium removing agent. ... Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a
Matched Categories: … Compounds used in a research, industrial, or household setting …
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Description: … and amphetamines, have a high potential for abuse and dependence. ... Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention ... associated with many stimulant-associated side effects and an increase in abuse potential, which is a
Bos taurus skin or pelt is used in allergenic testing.
Approved
Artemisia californica pollen is the pollen of the Artemisia californica plant. Artemisia californica pollen is mainly used in allergenic testing.
Approved
Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti.
Approved
Matched Iupac: … 5,9b-difluoro-10-hydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. ... Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated …
Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Iupac: … 9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Acer macrophyllum pollen is the pollen of the Acer macrophyllum plant. Acer macrophyllum pollen is mainly used in allergenic testing.
Approved
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Description: … neutralizing VEGF-A. ... There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important ... lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a
Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … Acromegaly is a life-threatening disease requiring life-long management. ... Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues ... [L14501] Octreotide is a long-acting drug with pharmacologic activities that mimic those of the natural …
Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
Approved
Illicit
Matched Description: … Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate ... Talbutal is a schedule III drug in the U.S. …
Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. One study in 1976 demonstrated that metrizoic acid, when used for cardiac angiography, was well tolerated. A total of...
Approved
Matched Description: … Metrizoic acid is a molecule used as a contrast medium. ... over a three-year period. ... It present a higher risk of allergic reactions due to its high osmolality. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams,...
Approved
Withdrawn
Matched Description: … Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.
Approved
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Poa compressa pollen is the pollen of the Poa compressa plant. Poa compressa pollen is mainly used in allergenic testing.
Approved
Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Approved
Matched Description: … Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. …
Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% . As vitamin C is susceptible to breakdown of compound...
Approved
Matched Description: … Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ... an antioxidant action to act as a free radical scavenger and increases collagen production *in vitro ... While ascorbyl phosphate salts provide a constant delivery of vitamin C into the skin, they also mediate …
An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Approved
Matched Description: … It also acts as a chemosterilant for male houseflies and other insects. …
Anser anser feather is used in allergenic testing.
Approved
Silver nitrate is an inorganic compound with the chemical formula AgNO3. In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. It is often used as a precursor to other silver-containing compounds. It is used in making photographic films, and in laboratory setting as a staining agent...
Approved
Investigational
Matched Description: … It is often used as a precursor to other silver-containing compounds. ... In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. ... It is used in making photographic films, and in laboratory setting as a staining agent in protein visualization …
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Description: … Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 451 - 475 of 11603 in total