Displaying drugs 1126 - 1150 of 15670 in total
Salsola kali pollen
Salsola kali pollen is the pollen of the Salsola kali plant. Salsola kali pollen is mainly used in allergenic testing.
Approved
Matched Description: … Salsola kali pollen is mainly used in allergenic testing. …
Ambrosia tenuifolia pollen
Ambrosia tenuifolia pollen is the pollen of the Ambrosia tenuifolia plant. Ambrosia tenuifolia pollen is mainly used in allergenic testing.
Approved
Matched Description: … Ambrosia tenuifolia pollen is mainly used in allergenic testing. …
Juniperus occidentalis pollen
Juniperus occidentalis pollen is the pollen of the Juniperus occidentalis plant. Juniperus occidentalis pollen is mainly used in allergenic testing.
Approved
Matched Description: … Juniperus occidentalis pollen is mainly used in allergenic testing. …
Pepsin
Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products .
Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated...
Approved
Experimental
Investigational
Matched Synonyms: … Pepsin A …
Matched Description: … Pepsin is approved by the FDA and is used in food at levels not to exceed current good manufacturing ... Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, ... Interestingly, it has been used as a marker for laryngopharyngeal reflux (LPR), which is a common illness …
Matched Categories: … Pepsin A, antagonists & inhibitors …
Matched Description: … Pepsin is approved by the FDA and is used in food at levels not to exceed current good manufacturing ... Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, ... Interestingly, it has been used as a marker for laryngopharyngeal reflux (LPR), which is a common illness …
Matched Categories: … Pepsin A, antagonists & inhibitors …
Sacituzumab govitecan
Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2...
Approved
Investigational
Matched Description: … antigen 2 (TROP-2) antibody with the topoisomerase I inhibitor SN-38. ... advance in cancer treatment. ... the brand name Trodelvy™ by Immunomedics, Inc.; it is currently indicated under accelerated approval for …
Matched Categories: … Trop-2-Directed Monoclonal Antibodies …
Matched Categories: … Trop-2-Directed Monoclonal Antibodies …
Creatine
An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Matched Iupac: … 2-(N-methylcarbamimidamido)acetic acid …
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. ... Creatine is excreted as creatinine in the urine. ... In muscle tissue, creatine generally occurs as phosphocreatine. …
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. ... Creatine is excreted as creatinine in the urine. ... In muscle tissue, creatine generally occurs as phosphocreatine. …
Propylhexedrine
Propylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. It is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies.
Approved
Matched Iupac: … (1-cyclohexylpropan-2-yl)(methyl)amine …
Matched Description: … Propylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. ... It is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies. …
Matched Description: … Propylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. ... It is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies. …
Bepridil
A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. It is no longer marketed in the United States, as it has been implicated in causing...
Approved
Withdrawn
Matched Iupac: … N-benzyl-N-[3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl]aniline …
Matched Description: … It is no longer marketed in the United States, as it has been implicated in causing ventricular arrhythmias ... A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. ... It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. …
Matched Salts cas: … 74764-40-2 …
Matched Description: … It is no longer marketed in the United States, as it has been implicated in causing ventricular arrhythmias ... A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. ... It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. …
Matched Salts cas: … 74764-40-2 …
Sulfameter
Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Approved
Matched Iupac: … 4-amino-N-(5-methoxypyrimidin-2-yl)benzene-1-sulfonamide …
Matched Description: … Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Description: … Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Botulinum toxin type B
Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation and chromatography steps.
Approved
Investigational
Matched Description: … The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin ... The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation …
Tepotinib
Tepotinib is a MET tyrosine kinase inhibitor intended to treat a variety of MET-overexpressing solid tumors. It was originally developed in partnership between EMD Serono and the University of Texas M.D. Anderson Cancer Center in 2009 and has since been investigated in the treatment of neuroblastoma, gastric cancers, non-small cell...
Approved
Investigational
Matched Iupac: … 3-{1-[(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}phenyl)methyl]-6-oxo-1,6-dihydropyridazin ... -3-yl}benzonitrile …
Matched Description: … In February 2022, tepotinib was approved for use in Europe.[L42200] ... [A228058] MET is a desirable target in the treatment of certain solid tumors as it appears to play a ... Tepotinib was first approved in Japan in March 2020 for the treatment of non-small cell lung cancers …
Matched Categories: … MATE 2 Inhibitors ... Proto-Oncogene Proteins c-met, antagonists & inhibitors …
Matched Description: … In February 2022, tepotinib was approved for use in Europe.[L42200] ... [A228058] MET is a desirable target in the treatment of certain solid tumors as it appears to play a ... Tepotinib was first approved in Japan in March 2020 for the treatment of non-small cell lung cancers …
Matched Categories: … MATE 2 Inhibitors ... Proto-Oncogene Proteins c-met, antagonists & inhibitors …
Physostigmine
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Approved
Investigational
Matched Description: … A cholinesterase inhibitor that is rapidly absorbed through membranes. ... also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Rumex salicifolius var. mexicanus pollen
Rumex salicifolius var. mexicanus pollen is the pollen of the Rumex salicifolius var. mexicanus plant. Rumex salicifolius var. mexicanus pollen is mainly used in allergenic testing.
Approved
Matched Description: … Rumex salicifolius var. mexicanus pollen is mainly used in allergenic testing. …
Tafamidis
Tafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives developed by FoldRX. Tafamidis is structurally similar to diflusinal. Tafamidis was granted an EMA market authorisation on 16 November 2011 and FDA approval on 3 May 2019.
Approved
Investigational
Matched Iupac: … 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid …
Matched Description: … Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Platanus hybrida pollen
Platanus hybrida pollen is the pollen of the Platanus hybrida plant. Platanus hybrida pollen is mainly used in allergenic testing.
Approved
Matched Description: … Platanus hybrida pollen is mainly used in allergenic testing. …
Sibutramine
Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the...
Approved
Illicit
Investigational
Withdrawn
Matched Iupac: … {1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}dimethylamine …
Matched Description: … increases the risk of heart attack and stroke in patients with a history of heart disease. ... hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. ... It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule …
Matched Description: … increases the risk of heart attack and stroke in patients with a history of heart disease. ... hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. ... It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule …
Abaloparatide
Abaloparatide is an N-terminal analog of parathyroid hormone-related protein (PTHrP) and an agonist at the parathyroid hormone type 1 (PTH1) receptor. It is a synthetic 34 amino acid peptide with 41% homology to human parathyroid hormone 1-34 and human PTHrP 1-34. Abaloparatide and PTHrP share the first 21 amino acids...
Approved
Investigational
Matched Description: … [L740] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended abaloparatide ... [L740] It is a synthetic 34 amino acid peptide with 41% homology to human parathyroid hormone 1-34 and ... in postmenopausal women and is also used to increase bone density in men with osteoporosis. …
Sodium tartrate
Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient. It acts as an emulsifier and pH...
Approved
Matched Description: … It acts as an emulsifier and pH control agent in food products [L2590]. ... It is obtained as a byproduct of wine manufacturing. ... This compound is commonly used as an emulsifier in cheese/cheese spread products and is not to exceed …
Matched Categories: … Drugs for Constipation …
Matched Categories: … Drugs for Constipation …
Pitolisant
Pitolisant is a selective antagonist or inverse agonist of the histamine H3 receptor used to treat type 1 or 2 narcolepsy. Narcolepsy is a chronic neurological disorder that affects 1 in 2,000 individuals and is characterized by excessive daytime sleepiness, abnormal REM sleep manifestations, sleep paralysis and hypnagogic hallucinations. About...
Approved
Investigational
Matched Iupac: … 1-{3-[3-(4-chlorophenyl)propoxy]propyl}piperidine …
Matched Description: … 1 or 2 narcolepsy. ... In a European clinical trial of adult patients with narcolepsy, there was a reduction in the Epworth ... FDA approved the use of pitolisant in 2019 for excessive daytime sleepiness (EDS) associated with narcolepsy …
Matched Salts cas: … 903576-44-3 …
Matched Categories: … Histamine-3 Receptor Antagonist/Inverse Agonist ... Histamine-3 (H3) Receptor Antagonists/Inverse Agonists …
Matched Description: … 1 or 2 narcolepsy. ... In a European clinical trial of adult patients with narcolepsy, there was a reduction in the Epworth ... FDA approved the use of pitolisant in 2019 for excessive daytime sleepiness (EDS) associated with narcolepsy …
Matched Salts cas: … 903576-44-3 …
Matched Categories: … Histamine-3 Receptor Antagonist/Inverse Agonist ... Histamine-3 (H3) Receptor Antagonists/Inverse Agonists …
Metreleptin
Metreleptin, a recombinant analog of the human hormone leptin, is an orphan drug used to treat complications of leptin deficiency in people with lipodystrophy. Lipodystrophies include a range of disorders characterized by the reduction, absence, or altered distribution of adipose tissue. Complications of lipodystrophy include metabolic abnormalities such as hypertriglyceridemia,...
Approved
Matched Description: … [L41315] Metreleptin was approved by Health Canada in January 2024 for the same patient population, in ... [L41315]
In February 2014, metreleptin was approved by the FDA for the treatment of complications ... Metreleptin is produced in _E. coli_ and differs from native human leptin by the addition of a methionine …
Pimethixene
Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.
Approved
Matched Description: … Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. ... It is an anticholinergic used in the treatment of bronchitis. …
Matched Categories: … Antihistamines for Systemic Use ... Heterocyclic Compounds, 3-Ring …
Matched Categories: … Antihistamines for Systemic Use ... Heterocyclic Compounds, 3-Ring …
Trovafloxacin
Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was shown to be more effective...
Approved
Investigational
Withdrawn
Matched Iupac: … 7-[(1R,5S,6S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro ... -1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan ... It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Description: … Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan ... It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Procaine benzylpenicillin
Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. Procaine benzylpenicillin is administered by deep intramuscular injection. It...
Approved
Vet approved
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... ; 2-(diethylamino)ethyl 4-aminobenzoate …
Matched Description: … Benzylpenicillin is active against a wide range of organisms and is the drug of first choice for many ... It is widely used in veterinary settings. ... (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. …
Matched Mixtures name: … Bicillin C-R 900/300 ... Bicillin A-P Injection Pws …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Description: … Benzylpenicillin is active against a wide range of organisms and is the drug of first choice for many ... It is widely used in veterinary settings. ... (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. …
Matched Mixtures name: … Bicillin C-R 900/300 ... Bicillin A-P Injection Pws …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Pefloxacin
A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Approved
Matched Iupac: … 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Description: … A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Lomifylline
Approved
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Obstructive Airway Diseases …
Displaying drugs 1126 - 1150 of 15670 in total