Displaying drugs 1201 - 1225 of 15697 in total
Tyrothricin
Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis and Bacillus aneurinolyticus . This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely of the six predominant tyrocidines, TrcA/A1,...
Approved
Matched Description: … does demonstrate systemic toxicity [L4019, L4021, L4022], although certain formulations that are safe for ... This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely ... /C1, and other more minor contributors) and 40% neutral linear gramicidins (where valine-gramicidin A …
Matched Categories: … Antibiotics for Topical Use …
Matched Categories: … Antibiotics for Topical Use …
Larotrectinib
Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and...
Approved
Investigational
Matched Iupac: … (3S)-N-{5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl}-3-hydroxypyrrolidine …
Matched Description: … kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important ... [L49821] Larotrectinib was granted accelerated approval by the FDA in November 2018 for the treatment ... Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine …
Matched Description: … kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important ... [L49821] Larotrectinib was granted accelerated approval by the FDA in November 2018 for the treatment ... Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine …
Thyroid, porcine
Thyroid extract is dried and powdered thyroid glands from pigs containing tiiodothyronine (T3) and thyroxine (T4) used to supplement low or absent thyroid activity.[A190831,L11755] Thyroid extract has been described in literature to treat hypothyroidism since 1891 but its use dates back as far as the 6th century. Thyroid extract is...
Approved
Matched Description: … [A190831] Thyroid extract is no longer considered a first line therapy as it delivers a dose that is ... [A190831,L11755] Thyroid extract has been described in literature to treat hypothyroidism since 1891[ ... [A190813]
Thyroid extracts were never FDA approved as their use in the United States predates the …
Chymotrypsin
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Synonyms: … Chymotrypsin A …
Matched Description: … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins ... proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in …
Matched Description: … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins ... proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in …
Buclizine
Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Matched Description: … [A178102] In addition to the above conditions, buclizine has been studied in the treatment of migraine ... in the syrup form, however, this indication has not been validated. ... attacks and in the treatment of nausea and vomiting during pregnancy. …
Matched Categories: … Antihistamines for Systemic Use …
Matched Categories: … Antihistamines for Systemic Use …
Setmelanotide
Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. It is an agonist of the melanocortin 4 receptor. Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. Other...
Approved
Investigational
Matched Iupac: … (4R,7S,10S,13R,16S,19R,22R)-13-benzyl-22-[(2S)-5-[(diaminomethylidene)amino]-2-acetamidopentanamido]- ... 10-{3-[(diaminomethylidene)amino]propyl}-16-[(1H-imidazol-5-yl)methyl]-7-[(1H-indol-3-yl)methyl]-19-methyl …
Matched Description: … attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in ... [A224449] Other earlier treatments for these patients included gastric bypass surgery. ... Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin …
Matched Description: … attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in ... [A224449] Other earlier treatments for these patients included gastric bypass surgery. ... Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin …
Vericiguat
Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Iupac: … methyl N-(4,6-diamino-2-{5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin …
Matched Description: … a relatively long half-life and allowing for once-daily dosing. ... [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis ... Verquvo - for use in certain patients with systolic heart failure. …
Matched Categories: … Vasodilators Used in Cardiac Diseases …
Matched Description: … a relatively long half-life and allowing for once-daily dosing. ... [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis ... Verquvo - for use in certain patients with systolic heart failure. …
Matched Categories: … Vasodilators Used in Cardiac Diseases …
Magaldrate
Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Approved
Withdrawn
Matched Iupac: … pentaaluminium(3+) decamagnesium(2+) hydrate hentriacontahydroxide disulfate …
Matched Description: … Magaldrate has been discontinued in the US market. ... Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and …
Matched Categories: … Drugs for Acid Related Disorders …
Matched Description: … Magaldrate has been discontinued in the US market. ... Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and …
Matched Categories: … Drugs for Acid Related Disorders …
Corticotropin
Corticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis.
Approved
Investigational
Vet approved
Matched Description: … It is an important player in the hypothalamic-pituitary-adrenal axis. ... Corticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by …
Matched Categories: … Corticosteroids for Systemic Use …
Matched Categories: … Corticosteroids for Systemic Use …
Lomitapide
Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial hypercholesterolemia (HoFH) patients. It is marketed under the name Juxtapid (R).
Approved
Investigational
Matched Iupac: … N-(2,2,2-trifluoroethyl)-9-(4-{4-[4'-(trifluoromethyl)-[1,1'-biphenyl]-2-amido]piperidin-1-yl}butyl)- …
Matched Description: … Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Description: … Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Niraparib
Niraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. Niraparib is selective towards PARP-1 and PARP-2. First approved by the FDA on March 27, 2017, niraparib is used to treat epithelial ovarian, fallopian tube, or...
Approved
Investigational
Matched Iupac: … 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide …
Matched Description: … By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. ... [L43277] Niraparib is selective towards PARP-1 and PARP-2. …
Matched Categories: … MATE 2 Substrates with a Narrow Therapeutic Index ... MATE 2 Inhibitors ... MATE 2 Substrates ... MATE 1 Substrates with a Narrow Therapeutic Index ... Heterocyclic Compounds, 2-Ring …
Matched Description: … By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. ... [L43277] Niraparib is selective towards PARP-1 and PARP-2. …
Matched Categories: … MATE 2 Substrates with a Narrow Therapeutic Index ... MATE 2 Inhibitors ... MATE 2 Substrates ... MATE 1 Substrates with a Narrow Therapeutic Index ... Heterocyclic Compounds, 2-Ring …
Acetohydroxamic acid
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics...
Approved
Matched Description: … Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure ... In the urine, it acts as an antagonist of the bacterial enzyme urease. ... It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary …
Lidoflazine
Approved
Experimental
Matched Iupac: … 2-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-N-(2,6-dimethylphenyl)acetamide …
Gluconic Acid
Commonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Approved
Investigational
Matched Description: … Commonly found in salts with sodium and calcium. …
Matched Mixtures name: … Plasma-Lyte A ... Isolyte S in Dextrose ... PLASMA-LYTE A INJECTION …
Matched Mixtures name: … Plasma-Lyte A ... Isolyte S in Dextrose ... PLASMA-LYTE A INJECTION …
Mestranol
The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Approved
Matched Iupac: … 3aS,3bR,9bS,11aS)-1-ethynyl-7-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. …
Matched Mixtures name: … LUTORAL-E …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Description: … The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. …
Matched Mixtures name: … LUTORAL-E …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Bepotastine
Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe Seiyaku Co., Ltd. under the brand name Talion. It is available...
Approved
Matched Iupac: … 4-{4-[(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidin-1-yl}butanoic acid …
Matched Description: … Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus ... Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. ... It is available in oral and opthalmic dosage forms in Japan. …
Matched Description: … Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus ... Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. ... It is available in oral and opthalmic dosage forms in Japan. …
Dacomitinib
Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Iupac: … (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide …
Matched Description: … [L4810] Some evidence in the literature suggests the therapeutic potential of dacomitinib in the epithelial ... Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … [L4810] Some evidence in the literature suggests the therapeutic potential of dacomitinib in the epithelial ... Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Obiltoxaximab
Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin. Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa.
Approved
Matched Description: … Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of ... Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Categories: … Antiinfectives for Systemic Use …
Plecanatide
Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age
Approved
Investigational
Matched Iupac: … (4S)-4-{[(2S)-2-{[(2S)-2-amino-1-hydroxy-3-(C-hydroxycarbonimidoyl)propylidene]amino}-3-carboxy-1-hydroxypropylidene ... }-22-(2-carboxyethyl)-3,6,9,12,15,18,21,24,30,33,36-undecahydroxy-10-[(C-hydroxycarbonimidoyl)methyl] ... ]amino}-4-{[(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-38-{[(1S)-1-carboxy-3-methylbutyl]-C-hydroxycarbonimidoyl ... -32-[(1R)-1-hydroxyethyl]-4-methyl-19-(2-methylpropyl)-7,13-bis(propan-2-yl)-27,28,40,41-tetrathia-2,5,8,11,14,17,20,23,31,34,37 ... -undecaazabicyclo[14.13.13]dotetraconta-2,5,8,11,14,17,20,23,30,33,36-undecaen-25-yl]-C-hydroxycarbonimidoyl …
Matched Description: … Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation ... It should not be used in children less than six years of age, and should be avoided in patients six years …
Matched Categories: … Drugs for Constipation ... Guanylate Cyclase-C Agonist ... Guanylyl Cyclase C Agonists …
Matched Description: … Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation ... It should not be used in children less than six years of age, and should be avoided in patients six years …
Matched Categories: … Drugs for Constipation ... Guanylate Cyclase-C Agonist ... Guanylyl Cyclase C Agonists …
Propantheline
A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Approved
Matched Iupac: … methylbis(propan-2-yl)[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium …
Matched Description: … A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment ... At high doses it has nicotinic effects resulting in neuromuscular blocking. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Drugs for Functional Gastrointestinal Disorders …
Matched Description: … A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment ... At high doses it has nicotinic effects resulting in neuromuscular blocking. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Drugs for Functional Gastrointestinal Disorders …
Baloxavir marboxil
Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of baloxavir with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl...
Approved
Investigational
Matched Iupac: … {[(3R)-2-[(2S)-12,13-difluoro-9-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl]-9,12 …
Matched Description: … More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza ... [A251760] Baloxavir marboxil was first globally approved in Japan in February 2018,[A39895] followed ... by the US approval in October, 2018. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADET ... XOFLUZA 40 MG FİLM KAPLI TABLET, 2 ADET …
Matched Description: … More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza ... [A251760] Baloxavir marboxil was first globally approved in Japan in February 2018,[A39895] followed ... by the US approval in October, 2018. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADET ... XOFLUZA 40 MG FİLM KAPLI TABLET, 2 ADET …
Sodium stibogluconate
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Iupac: … trisodium (3R,4S,5R)-1-{[(3R,4S,5R)-3-carboxylato-5-[(1R)-1,2-dihydroxyethyl]-1-oxido-2,6,7-trioxa-1- ... 2.2.1]heptan-1-yl]oxy}-5-[(1R)-1,2-dihydroxyethyl]-1-hydroxy-2,6,7-trioxa-1-stibabicyclo[2.2.1]heptane-3- …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration ... Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). ... Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration ... Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). ... Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world …
Tioconazole
Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Iupac: … 1-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole …
Matched Description: … Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus ... In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability. …
Matched Mixtures name: … TRİVAG 300 MG / 200 MG/ 100 MG OVÜL, 3 ADET ... GYNOMAX XL 200 MG/ 300 MG/100 MG VAJINAL OVÜL, 3 ADET …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Matched Description: … Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus ... In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability. …
Matched Mixtures name: … TRİVAG 300 MG / 200 MG/ 100 MG OVÜL, 3 ADET ... GYNOMAX XL 200 MG/ 300 MG/100 MG VAJINAL OVÜL, 3 ADET …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Rifaximin
Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of...
Approved
Investigational
Matched Description: … It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction ... Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not ... pass the gastrointestinal wall into the circulation as is common for other types of orally administered …
Matched Categories: … Antibiotics for Topical Use …
Matched Products: … RIFAXIMINA 2% ... RIFAXIGAL® 100MG/5ML POLVO PARA RECONSTITUIR A SUSPENSION ORAL ... RIFAX 2% - POLVO PARA RECONSTITUIR SUSPENSIONORAL …
Matched Categories: … Antibiotics for Topical Use …
Matched Products: … RIFAXIMINA 2% ... RIFAXIGAL® 100MG/5ML POLVO PARA RECONSTITUIR A SUSPENSION ORAL ... RIFAX 2% - POLVO PARA RECONSTITUIR SUSPENSIONORAL …
Belzutifan
Belzutifan is an inhibitor of hypoxia-inducible factor 2α (HIF-2α) used in the treatment of von Hippel-Lindau (VHL) disease-associated cancers. The HIF-2α protein was first identified in the 1990s by researchers at UT Southwestern Medical Center as a key player in the growth of certain cancers. Initially considered to be undruggable,...
Approved
Investigational
Matched Iupac: … 3-{[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methanesulfonyl-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile …
Matched Description: … Center as a key player in the growth of certain cancers. ... [L36105] Initially considered to be undruggable, a binding pocket was eventually discovered in the HIF ... -2α molecule which allowed for compounds to bind and inhibit these proteins. …
Matched Categories: … MATE 2 Inhibitors …
Matched Description: … Center as a key player in the growth of certain cancers. ... [L36105] Initially considered to be undruggable, a binding pocket was eventually discovered in the HIF ... -2α molecule which allowed for compounds to bind and inhibit these proteins. …
Matched Categories: … MATE 2 Inhibitors …
Displaying drugs 1201 - 1225 of 15697 in total