Displaying drugs 1226 - 1250 of 15697 in total
Levonordefrin
Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Approved
Matched Iupac: … 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol …
Matched Description: … Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry. …
Matched Mixtures name: … Scandonest 2% L ... Isocaine HCl Inj 2% ... Carbocaine 2% With Neo-cobefrin …
Matched Description: … Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry. …
Matched Mixtures name: … Scandonest 2% L ... Isocaine HCl Inj 2% ... Carbocaine 2% With Neo-cobefrin …
Curcuma aromatica root oil
Curcuma aromatica root oil is obtained from the roots of Curcuma aromatica, or more commonly called wild tumeric, via steamed distillation. Curcuma aromatica belongs to the family Zingiberaceae. The wild ginger has been used as a cosmetic herbal where its rhizomes exhibit a distinct fragrance and color. The major constituents...
Approved
Matched Description: … The wild ginger has been used as a cosmetic herbal where its rhizomes exhibit a distinct fragrance and …
Droxidopa
Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. There is a...
Approved
Investigational
Matched Iupac: … (2S,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid …
Matched Description: … Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. ... It is approved for use in Japan and is currently in trials in the U.S. ... There is a deficit of noradrenaline as well as of dopamine in Parkinson's disease and it has been proposed …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
Matched Description: … Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. ... It is approved for use in Japan and is currently in trials in the U.S. ... There is a deficit of noradrenaline as well as of dopamine in Parkinson's disease and it has been proposed …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
Dibenzepin
Dibenzepin is approved for use in Europe.
Approved
Matched Iupac: … 9-[2-(dimethylamino)ethyl]-2-methyl-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen …
Matched Description: … Dibenzepin is approved for use in Europe. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Description: … Dibenzepin is approved for use in Europe. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Troglitazone
Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.
Approved
Investigational
Withdrawn
Matched Iupac: … 5-({4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-yl)methoxy]phenyl}methyl)-1,3-thiazolidine …
Matched Description: … Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. …
Matched Categories: … Drugs Used in Diabetes ... Heterocyclic Compounds, 2-Ring …
Matched Description: … Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. …
Matched Categories: … Drugs Used in Diabetes ... Heterocyclic Compounds, 2-Ring …
Cyanocobalamin Co-60
Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons.
Approved
Withdrawn
Matched Iupac: … (60Co)cobalt(3+) (2R,3S,4S,6Z,8S,9S,11Z,14S,16Z,18R,19R)-4,9,14-tris(2-carbamoylethyl)-3,8,19-tris(carbamoylmethyl ... [15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-ide iminomethanide ... )-18-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl) ... oxolan-3-yl phosphonato]oxy}propyl]carbamoyl}ethyl)-2,3,6,8,13,13,16,18-octamethyl-20,21,22,23-tetraazapentacyclo …
Matched Description: … market in the US for unknown reasons. ... Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the …
Matched Description: … market in the US for unknown reasons. ... Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the …
Lumefantrine co-artemether
Lumefantrine Co-Artemether (Riamet) has been investigated for the treatment of Malaria, Malaria, Falciparum, Malaria in Pregnancy, Uncomplicated Malaria, and Uncomplicated Knowlesi Malaria. Lumefantrine Co-Artemether is a tablet formulation of artemether and lumefantrine, a well-tolerated, fast-acting and effective blood schizontocidal drug that serves primarily in the treatment of uncomplicated falciparum malaria...
Approved
Investigational
Matched Description: … and a decrease in recrudescence rate. ... Unlike artemether, lumefantrine has a slower onset of action, resulting in clearance of residual parasites ... Lumefantrine Co-Artemether (Riamet) has been investigated for the treatment of Malaria, Malaria, Falciparum …
Iodide I-123
Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland. After incorporation, a gamma camera is used to detect...
Approved
Matched Description: … Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for ... Radioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h ( ... hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared …
Matched Salts cas: … 41927-88-2 …
Matched Salts cas: … 41927-88-2 …
Technetium Tc-99m succimer
Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA), is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorders. It works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma...
Approved
Matched Description: … >99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA),[A245643] is a ... radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in patients ... [L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Mirikizumab
Mirikizumab is a monoclonal antibody developed by Eli Lilly intended to treat ulcerative colitis. It inhibits the actions of interleukin-23 (IL-23), a pro-inflammatory cytokine that activates pathways contributing to the development of inflammatory diseases.[L46237,L46257]
Mirikizumab is approved in Japan and received a positive opinion from the EMA's Committee for Medicinal...
Approved
Investigational
Matched Description: … EMA's Committee for Medicinal Products for Human Use in March 2023. ... [L46237,L46257]
Mirikizumab is approved in Japan[L46252] and received a positive opinion from the ... was eventually approved in the US in October 2023[L48651] for the treatment of adult patients with moderate-to-severely …
Plicamycin
Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued plicamycin in 2000.
Approved
Investigational
Withdrawn
Matched Iupac: … (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5S,6R)-4-{[(2S ... ,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan ... -2-yl]oxy}-6-{[(2S,4R,5R,6R)-4-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan ... -2-yl]oxy}-8,9-dihydroxy-7-methyl-1,2,3,4-tetrahydroanthracen-1-one …
Matched Description: … The manufacturer discontinued plicamycin in 2000. ... It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … The manufacturer discontinued plicamycin in 2000. ... It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sitaxentan
Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008. In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity.
Approved
Investigational
Withdrawn
Matched Iupac: … N-(4-chloro-3-methyl-1,2-oxazol-5-yl)-2-[2-(6-methyl-2H-1,3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide …
Matched Description: … Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension ... (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008. ... In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity. …
Matched Salts cas: … 210421-74-2 …
Matched Categories: … Antihypertensives for Pulmonary Arterial Hypertension …
Matched Description: … Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension ... (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008. ... In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity. …
Matched Salts cas: … 210421-74-2 …
Matched Categories: … Antihypertensives for Pulmonary Arterial Hypertension …
Lurasidone
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Iupac: … (1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}-4-azatricyclo …
Matched Description: … pending approval for the treatment of bipolar disorder in the United States. ... Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Salts cas: … 367514-88-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
Matched Description: … pending approval for the treatment of bipolar disorder in the United States. ... Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Salts cas: … 367514-88-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
Dofetilide
Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Approved
Investigational
Matched Iupac: … N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide …
Matched Description: … FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation ... Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration ( ... and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter …
Matched Categories: … OCT2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation ... Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration ( ... and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter …
Matched Categories: … OCT2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Starch, corn
Corn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. Starch...
Approved
Nutraceutical
Matched Description: … found in topical drugs as a skin protectant. ... Corn starch may be added in some food products as a thickening agent or anti-caking agent, and is sometimes ... Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Imiquimod
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched Synonyms: … 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine ... 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline …
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Description: … Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. ... Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Description: … Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. ... Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bumadizone
Bumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis and gout . Its use is restricted to these conditions, due to risks this drug poses .
Approved
Matched Iupac: … 2-(N,N'-diphenylhydrazinecarbonyl)hexanoic acid …
Matched Description: … Bumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic ... , and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis and gout …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Description: … Bumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic ... , and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis and gout …
Matched Categories: … Non COX-2 selective NSAIDS …
Pralsetinib
Pralsetinib, similar to the previously approved selpercatinib, is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A219751, L15986] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers, including non-small cell lung cancer. Although multikinase inhibitors, including cabozantinib, ponatinib,...
Approved
Investigational
Matched Iupac: … -1H-pyrazol-3-yl)amino]pyrimidin-2-yl}cyclohexane-1-carboxamide ... (1s,4s)-N-[(1S)-1-[6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl]ethyl]-1-methoxy-4-{4-methyl-6-[(5-methyl …
Matched Description: … [A202049, A202055, L15986] Although a phase 1/2 trial of pralsetinib termed ARROW (NCT03037385) is ... including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and [vandetanib], have shown efficacy in ... specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes. …
Matched Categories: … MATE 2 Inhibitors …
Matched Description: … [A202049, A202055, L15986] Although a phase 1/2 trial of pralsetinib termed ARROW (NCT03037385) is ... including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and [vandetanib], have shown efficacy in ... specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes. …
Matched Categories: … MATE 2 Inhibitors …
Hydroxyzine
Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Iupac: … 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethan-1-ol …
Matched Description: … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment ... Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane ... L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in …
Matched Salts cas: … 2192-20-3 …
Matched Products: … HIDROXIZINACLOHIDRATO 100 MG / 2 MLSOLUCION INYECTABLE …
Matched Description: … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment ... Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane ... L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in …
Matched Salts cas: … 2192-20-3 …
Matched Products: … HIDROXIZINACLOHIDRATO 100 MG / 2 MLSOLUCION INYECTABLE …
Remoxipride
Remoxipride is an atypical antipsychotic agent that is specific for dopamine D2 receptors. It gained approval in the UK in 1989 but was withdrawn in 1993 after it was found to be associated with an increased incidence of aplastic anemia.[A215422,A215512]
Approved
Withdrawn
Matched Iupac: … 3-bromo-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2,6-dimethoxybenzamide …
Matched Description: … Remoxipride is an atypical antipsychotic agent that is specific for dopamine D2 receptors. ... [A215422] It gained approval in the UK in 1989 but was withdrawn in 1993 after it was found to be associated …
Matched Description: … Remoxipride is an atypical antipsychotic agent that is specific for dopamine D2 receptors. ... [A215422] It gained approval in the UK in 1989 but was withdrawn in 1993 after it was found to be associated …
Phthalylsulfathiazole
Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
Approved
Matched Iupac: … 2-({4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}carbamoyl)benzoic acid …
Matched Description: … It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006]. ... Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. …
Matched Description: … It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006]. ... Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. …
Dexchlorpheniramine maleate
Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.
Approved
Matched Iupac: … (2Z)-but-2-enedioic acid; [(3S)-3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. …
Matched Products: … SOMIN TAB 2 mg ... POLARAX TABLET 2 mg ... DEXTRAMINE TABLET 2 mg …
Matched Description: … Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. …
Matched Products: … SOMIN TAB 2 mg ... POLARAX TABLET 2 mg ... DEXTRAMINE TABLET 2 mg …
Tannic acid
Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine....
Approved
Matched Iupac: … (2R,3R,4S,5R)-4,5,6-tris[3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyloxy)benzoyloxy]-2-{[3,4-dihydroxy-5- ... (3,4,5-trihydroxybenzoyloxy)benzoyloxy]methyl}oxan-3-yl 3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyloxy)benzoate …
Matched Description: … It acts as a weak acid. ... Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. ... In the old days it was used as antidote against different poisons. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … It acts as a weak acid. ... Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. ... In the old days it was used as antidote against different poisons. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 1226 - 1250 of 15697 in total