Displaying drugs 1126 - 1150 of 1588 in total
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) ... Alteplase,recombinant ... Alteplase, recombinant …
Matched Description: … Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. …
Matched Description: … Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. …
Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen
Approved
Investigational
Matched Name: … Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen …
Vonicog alfa
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Von willebrand factor (recombinant) ... Von willebrand factor, recombinant, human …
Matched Description: … Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. …
Matched Description: … Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. …
Somatrogon
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … Recombinant human growth hormone long acting (fused w beta chains of HCG) ... CTP-SOMATROPIN FUSION PROTEIN ... -SUBUNIT) FUSION PROTEIN WITH SOMATOTROPIN (HUMAN) FUSION PROTEIN WITH 118-145-CHORIONIC GONADOTROPIN …
Matched Description: … [A241515,L39362] The glycosylation and the presence of CTPs in the protein sequence prolongs the half-life ... longer-acting forms of growth hormone were developed to improve patient adherence and thus, improve the therapeutic ... Somatrogon is a long-acting recombinant human growth hormone. …
Matched Categories: … Recombinant Human Growth Hormone …
Matched Description: … [A241515,L39362] The glycosylation and the presence of CTPs in the protein sequence prolongs the half-life ... longer-acting forms of growth hormone were developed to improve patient adherence and thus, improve the therapeutic ... Somatrogon is a long-acting recombinant human growth hormone. …
Matched Categories: … Recombinant Human Growth Hormone …
Interferon beta-1b
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Synonyms: … Interferon beta 1b (recombinant) ... Interferon beta-1b,recombinant ... Recombinant interferon beta-1b …
Matched Categories: … Recombinant Human Interferon beta …
Matched Categories: … Recombinant Human Interferon beta …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Interferon alfa-2a,recombinant ... Interferon alfa-2a, recombinant ... Interferon alfa-2a (recombinant) …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). …
Catridecacog
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Factor XIII A-Subunit (Recombinant) ... Recombinant Coagulation Factor XIII ... Coagulation Factor XIII A-Subunit (recombinant) …
Matched Description: … technology where the target protein is grown in yeast and then isolated, the human form is isolated ... Tretten is manufactured as an intracellular, soluble protein in yeast (Saccharomyces cerevisiae) production ... Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of …
Matched Description: … technology where the target protein is grown in yeast and then isolated, the human form is isolated ... Tretten is manufactured as an intracellular, soluble protein in yeast (Saccharomyces cerevisiae) production ... Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of …
Somatotropin
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Synonyms: … Somatropin recombinant ... Recombinant human growth hormone ... Somatropin (recombinant DNA origin) …
Matched Description: … It has an identical primary protein structure to endogenous human growth hormone. ... of recombinant HGH. ... [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone …
Matched Categories: … Recombinant Human Growth Hormone …
Matched Description: … It has an identical primary protein structure to endogenous human growth hormone. ... of recombinant HGH. ... [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone …
Matched Categories: … Recombinant Human Growth Hormone …
Tagraxofusp
Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia coli.[A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018...
Approved
Investigational
Matched Synonyms: … Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor …
Matched Description: … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic …
Matched Categories: … Narrow Therapeutic Index Drugs ... Recombinant Proteins ... Recombinant Fusion Proteins …
Matched Description: … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic …
Matched Categories: … Narrow Therapeutic Index Drugs ... Recombinant Proteins ... Recombinant Fusion Proteins …
Desirudin
Desirudin is a direct inhibitor of human thrombin. It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide...
Approved
Matched Synonyms: … Desirudin recombinant ... 63-Desulfohirudin (recombinant) …
Matched Description: … It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant …
Matched Description: … It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant …
Rasburicase
Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Synonyms: … Recombinant urate oxidase …
Matched Description: … Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces …
Matched Categories: … Recombinant Proteins …
Matched Description: … Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces …
Matched Categories: … Recombinant Proteins …
Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup a. The vaccine contains N. meningitis serogroup a capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Investigational
Matched Synonyms: … Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains* N. meningitis* serogroup y capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Synonyms: … Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains N. meningitis serogroup W-135 capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Synonyms: … Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Interferon alfa-2b
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Interferon alfa-2b (recombinant) ... Interferon alfa-2b, recombinant …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). …
Matched Categories: … Narrow Therapeutic Index Drugs …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). …
Matched Categories: … Narrow Therapeutic Index Drugs …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … Velmanase alfa has an amino acid sequence of the monomeric protein identical to the naturally occurring ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy ... by the European Commission in March 2018 under the market name Lamzede [L39754] as the first human recombinant …
Matched Categories: … Recombinant Human Lysosomal alpha-Mannosidase …
Matched Description: … Velmanase alfa has an amino acid sequence of the monomeric protein identical to the naturally occurring ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy ... by the European Commission in March 2018 under the market name Lamzede [L39754] as the first human recombinant …
Matched Categories: … Recombinant Human Lysosomal alpha-Mannosidase …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. …
Laronidase
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Synonyms: … Human Recombinant alpha-L-iduronidase …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes …
Aldesleukin
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Recombinant human interleukin-2 ... Recombinant interleukin-2 human …
Matched Description: … Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E ... This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not …
Matched Categories: … Narrow Therapeutic Index Drugs …
Matched Description: … Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E ... This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not …
Matched Categories: … Narrow Therapeutic Index Drugs …
Lepirudin
Lepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct thrombin inhibitor.[L41539,L41569] Natural hirudin is an endogenous anticoagulant found in Hirudo medicinalis leeches. Lepirudin is produced in yeast cells and is identical to natural hirudin except for the absence of sulfate on...
Approved
Withdrawn
Matched Synonyms: … Lepirudin recombinant …
Matched Description: … Lepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct …
Matched Description: … Lepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct …
Follitropin
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … Follotropin recombinant ... Recombinant human follicle stimulating hormone beta ... Recombinant human follicle-stimulating hormone (r-HFSH) …
Matched Description: … Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which ... The nomenclature “beta” differentiates it from another recombinant human FSH product that was marketed …
Matched Description: … Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which ... The nomenclature “beta” differentiates it from another recombinant human FSH product that was marketed …
Insulin lispro
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Synonyms: … Insulin lispro recombinant ... Insulin lispro protamine recombinant …
Matched Description: … Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... Insulin lispro is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain …
Matched Description: … Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... Insulin lispro is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain …
Insulin glargine
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin glargine recombinant …
Matched Description: … [L34964] Insulin glargine is produced by recombinant DNA technology using a non-pathogenic laboratory ... Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... The resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4 allowing …
Matched Description: … [L34964] Insulin glargine is produced by recombinant DNA technology using a non-pathogenic laboratory ... Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... The resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4 allowing …
AstraZeneca COVID-19 Vaccine
The AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2.[L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another...
Approved
Investigational
Matched Synonyms: … ChAdOx1-S [recombinant] …
Matched Description: … manufacturer Advent Srl, consists of a replication-deficient adenovirus capable of producing the spike (S) protein …
Matched Description: … manufacturer Advent Srl, consists of a replication-deficient adenovirus capable of producing the spike (S) protein …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … Wap four-disulfide core domain protein 4 ... Recombinant secretory leucocyte protease inhibitor ... Recombinant secretory leukocyte protease inhibitor …
Displaying drugs 1126 - 1150 of 1588 in total