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Displaying drugs 226 - 250 of 14555 in total
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... of the virus) which results in an immunological defense against future exposure to the virus, or "antigen ... These vaccines provide protection from influenza by exposing the immune system to the virus (or parts …
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Approved
Investigational
Nutraceutical
Matched Description: … A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain ... It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. …
Matched Mixtures name: … The Classeum Co., Ltd. ... The Classeum Co., Ltd. ... The Classeum Co., Ltd. …
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2­ ol ... 1-(2­ hydroxypropyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … [A245503, A245508] In September 2017, FDA approved secnidazole under the market name Solosec for the ... to form a radical anion, thereby damaging and killing the target pathogen. ... treatment of trichomoniasis and bacterial vaginosis. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SECNICHEN POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... SECNIDAZOL PPS (POLVO PARA RECONSTITUIR A SUSPENSIÓN) ... SECNIPEN 750 MG POLVO PARA RECOSTRUIR A SUSPENSION ORAL …
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Synonyms: … (2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl …
Matched Description: … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild ... It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Synonyms: … (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol ... 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... projection system in the brain arising from the locus ceruleus. …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride ... Norepinephrine Bitartrate In 5% Dextrose Injection ... NORADRENALINA 1 MG / ML …
Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed...
Approved
Nutraceutical
Matched Iupac: … en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-1-ene ... 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1- …
Matched Description: … [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. ... Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene ... [T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS). …
Matched Mixtures name: … Formula #1 ... PNV Tabs 29-1 ... Trinatal Rx 1
Matched Categories: … Vitamin A
Matched Products: … Beta A 10000 Cap ... BETA-CAROTENE 15 MGPROVITAMIN A 25.000 IU …
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … [label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate ... still produces significant adverse effects in the GI tract. ... acting as a potent COX inhibitor similar in structure to [naproxen]. …
Matched Products: … DOLORSIN 1 G …
Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … [L1113] By the FDA, inositol is considered in the list of specific substances affirmed as generally recognized ... because even though its presence is vital in the body, a deficiency in this molecule does not translate ... Inositol is a collection of nine different stereoisomers but the name is usually used to describe only …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Hoa 1 ... Vege 1 Daily Tab …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Iupac: … 7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia-1- …
Matched Description: … [L49293] The beta-lactam ring of cefixime inhibits bacterial cell wall synthesis by binding to the penicillin-binding ... is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding ... final 3D structure of the bacterial cell wall which in turn inhibit bacterial cell wall peptidoglycan …
Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other...
Approved
Investigational
Matched Iupac: … 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-[(oxan-4-yl)amino]pyrazine …
Matched Description: … Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors ... [A40036] It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit ... -driven myelosuppression observed in other therapies. …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Matched Description: … It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for ... cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used ... (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424) …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Solutions Affecting the Electrolyte Balance …
Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles ... Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside In 0.9% Sodium Chloride …
Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues ... [L14513] In the past, octreotide has been administered solely by injection. ... [L14501] Octreotide is a long-acting drug with pharmacologic activities that mimic those of the natural …
Matched Products: … Siroctid 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,5 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,05 mg/ml Injektionslösung in einer Fertigspritze …
Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Approved
Investigational
Matched Description: … Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. ... Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of ... Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease. …
Matched Products: … VPRIV 400 ÜNİTE İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Iupac: … 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propyl-1H,4H-imidazo[4,3-f][1,2,4]triazin …
Matched Description: … the penis, resulting in an erection. ... in the smooth muscle cells of the corpus cavernosum. ... [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Drugs Used in Erectile Dysfunction …
Matched Products: … Vardenafil 1 A Pharma 5 mg - Filmtabletten ... Vardenafil 1 A Pharma 10 mg - Filmtabletten ... Vardenafil 1 A Pharma 20 mg - Filmtabletten …
Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Iupac: … (E)-3,3'-dioxo-1H,1'H,3H,3'H-[2,2'-biindolylidene]-5,5'-disulfonic acid …
Matched Description: … Indigotindisulfonic acid is a blue-colored dye with a variety of uses. ... [A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to ... This compound is an acid-base indicator and is used in the production of food colorants and pH tests. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Testosterone undecanoate is the ester prodrug of testosterone and has a mid-chain fatty acid at the carbon 17β position. It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone. There are oral and intramuscular formulations available for testosterone undecanoate: both formulations are indicated for...
Approved
Investigational
Matched Iupac: … phenanthren-1-yl undecanoate ... 9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Testosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the ... [L35970,L8932,L41355] Testosterone is a critical male hormone that is responsible for the normal ... growth and development of the male sex organs and for the maintenance of secondary sex characteristics …
Matched Products: … NEBIDO 250 MG/ML IM ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET …
Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly used Lewis acid....
Approved
Investigational
Matched Description: … In antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15% ... Aluminum chloride is a chemical compound with the chemical formula AlCl3. ... It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Hemox A
Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Description: … Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular ... [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. ... It is reported to exhibit potency that is 50-450 times higher than that of the first generation VEGFR …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Products: … INLYTA (TABLETS 1 MG) ... Axitinib STADA 1 mg Filmtabletten ... INLYTA ® 1 MG TABLETA RECUBIERTA …
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Description: … Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet ... Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical ... polypeptide chains that are bound together by disulfide bonds. …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … use in the stimulation of follicular development. ... surge, in females triggers ovulation and the development of the corpous luteum. ... It is a heterodimeric glycoprotein made up of monomeric units. …
Matched Mixtures name: … PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Products: … LUVERIS 75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Description: … The primary structure of the alpha-chain of r-hCG is identical to that of the alpha-chain of hCG, FSH …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Products: … OVITRELLE 250 MCG/0,5 ML KULLANIMA HAZIR ŞIRINGADA ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. Caused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are...
Approved
Investigational
Matched Description: … of life and increase the risk of mortality from cardiovascular disease. ... [L12144,L12147] It was developed by Esperion Therapeutics Inc. and approved by the FDA on February 21 ... [L12153] About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are insufficiently managed …
Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease.
Approved
Investigational
Matched Description: … Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery ... Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Diagnostic Uses of Chemicals …
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- …
Matched Description: … [L41715] The Vantas product was approved by the FDA in October 2004 for the palliative treatment of this ... As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by ... the FDA in May 2007). …
Displaying drugs 226 - 250 of 14555 in total