Displaying drugs 201 - 225 of 14555 in total
Labetalol
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730]
Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide ... 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up ... 25% of the mixture. ... [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Labetalol HCl in Dextrose ... Labetalol HCl in Sodium Chloride …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up ... 25% of the mixture. ... [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Labetalol HCl in Dextrose ... Labetalol HCl in Sodium Chloride …
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … of the PIGA gene. ... [A262566] Factor B is a positive regulator of the alternative complement pathway, where it activates ... the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … of the PIGA gene. ... [A262566] Factor B is a positive regulator of the alternative complement pathway, where it activates ... the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor …
Daptomycin
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … 21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1- ... carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28 …
Matched Description: … [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil ... Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive ... [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name …
Matched Products: … Daptomycin in Sodium Chloride ... CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... XAPTO 350 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Matched Description: … [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil ... Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive ... [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name …
Matched Products: … Daptomycin in Sodium Chloride ... CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... XAPTO 350 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Ivosidenib
Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of cancer cells. Ivosidenib was granted accelerated approval by the FDA...
Approved
Investigational
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-{1-[(2S)-1-(4-cyanopyridin-2-yl)-5-oxopyrrolidin-2-yl]-N-(5-fluoropyridin-3 …
Matched Description: … Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. ... [A248745] Ivosidenib was granted accelerated approval by the FDA in July 2018 for the treatment of ... [L46287] It was fully approved by the EMA in May 2023.[L46596] …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Heterocyclic Compounds, 1-Ring ... Isocitrate Dehydrogenase 1 Inhibitor ... Isocitrate Dehydrogenase-1 Inhibitors …
Matched Description: … Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. ... [A248745] Ivosidenib was granted accelerated approval by the FDA in July 2018 for the treatment of ... [L46287] It was fully approved by the EMA in May 2023.[L46596] …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Heterocyclic Compounds, 1-Ring ... Isocitrate Dehydrogenase 1 Inhibitor ... Isocitrate Dehydrogenase-1 Inhibitors …
Fentanyl
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone.
Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 1-phenethyl-4-N-propionylanilinopiperidine ... 1-Phenethyl-4-(N-phenylpropionamido)piperidine ... N-(1-phenethyl-4-piperidyl)propionanilide …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose ... Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... DUROGESIC SMAT 12 A 2.1MG ... DUROGESIC SMAT 25 A 4.2MG …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose ... Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... DUROGESIC SMAT 12 A 2.1MG ... DUROGESIC SMAT 25 A 4.2MG …
Vemurafenib
Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Iupac: … N-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide …
Matched Description: … [A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF. ... After approval, Roche in collaboration with Genentech launched a broad development program. [L1012] ... 17, 2011, under the company Hoffmann La Roche. …
Matched Categories: … combinations of sulfonamides ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … [A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF. ... After approval, Roche in collaboration with Genentech launched a broad development program. [L1012] ... 17, 2011, under the company Hoffmann La Roche. …
Matched Categories: … combinations of sulfonamides ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Crotamiton
Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.
Approved
Matched Description: … It is a colorless to slightly yellowish oil, having a faint amine-like odor. ... Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A-Bite Cream ... DERMITON % 10 LOSYON, 1 ŞIŞE …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A-Bite Cream ... DERMITON % 10 LOSYON, 1 ŞIŞE …
Infigratinib
Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational
Matched Iupac: … 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea …
Matched Description: … By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib ... [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR ... cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) fusion or another rearrangement …
Matched Salts cas: … 1310746-10-1 …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Receptor, Fibroblast Growth Factor, Type 1, antagonists & inhibitors …
Matched Description: … By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib ... [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR ... cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) fusion or another rearrangement …
Matched Salts cas: … 1310746-10-1 …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Receptor, Fibroblast Growth Factor, Type 1, antagonists & inhibitors …
Triclocarban
Triclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer...
Approved
Matched Synonyms: … 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Matched Description: … In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products ... It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products ... Triclocarban, with the chemical formula C13H9Cl3N2O [L2675] is an antibacterial agent that is particularly …
Matched Products: … NEXT 1 Anti-bacterial ... Next 1 Anti-Bacterial Sport ... Cuticura Medicated Soap Unscented 1% …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Matched Description: … In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products ... It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products ... Triclocarban, with the chemical formula C13H9Cl3N2O [L2675] is an antibacterial agent that is particularly …
Matched Products: … NEXT 1 Anti-bacterial ... Next 1 Anti-Bacterial Sport ... Cuticura Medicated Soap Unscented 1% …
Abatacept
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … Although approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different ... Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated ... of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. …
Matched Products: … ORENCIA Injection 125mg/ml in Prefilled Syringe …
Matched Products: … ORENCIA Injection 125mg/ml in Prefilled Syringe …
Dyphylline
Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Description: … It is typically used in the management of asthma, cardiac dyspnea, and bronchitis. ... Dyphylline is a theophylline derivative with broncho- and vasodilator properties. …
Matched Mixtures name: … ESPEKTAN A ŞURUP, 100 ML …
Matched Categories: … combinations of xanthines …
Matched Mixtures name: … ESPEKTAN A ŞURUP, 100 ML …
Matched Categories: … combinations of xanthines …
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem ... -7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Matched Salts cas: … 153773-82-1 …
Matched Products: … ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... ERTAGRAM® 1 G ... INVANZ 1 G IM/IV ENEJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Matched Salts cas: … 153773-82-1 …
Matched Products: … ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... ERTAGRAM® 1 G ... INVANZ 1 G IM/IV ENEJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Ketoconazole
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Iupac: … -1-yl]ethan-1-one ... 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin …
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol ... [A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in …
Matched Mixtures name: … Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% …
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Nizoral A-D ... A-BE LOTION ... FAZOL® SHAMPOO 1% …
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol ... [A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in …
Matched Mixtures name: … Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% …
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Nizoral A-D ... A-BE LOTION ... FAZOL® SHAMPOO 1% …
Zalcitabine
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Synonyms: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … elongation of DNA chains, thus resulting in the termination of viral DNA growth. ... A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by ... The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … elongation of DNA chains, thus resulting in the termination of viral DNA growth. ... A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by ... The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Oftasceine
Oftasceine is also referred to as Fluorexon. It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. It is a fluorescent dye or luminescent agent.
Approved
Matched Description: … It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. ... It is a fluorescent dye or luminescent agent. …
Delandistrogene moxeparvovec
Delandistrogene moxeparvovec is an adeno-associated virus vector-based gene therapy developed by Sarepta Therapeutics. It was granted accelerated approval by the FDA on June 22, 2023, as the first gene therapy to treat Duchenne Muscular Dystrophy (DMD). DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading...
Approved
Investigational
Matched Description: … [L47026] DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading ... It was granted accelerated approval by the FDA on June 22, 2023, as the first gene therapy to treat Duchenne ... serotype rh74 (AAVrh74) based vector containing the microdystrophin transgene under the control of a …
Isradipine
Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. Isradipine binds to calcium channels with high affinity and specificity...
Approved
Investigational
Matched Description: … the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells ... blocking agent of the DHP class. ... Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Esmolol
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate …
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker ... It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride ... BREVIBLOC FLAKON 10 MG/ML IV KULLANIM İÇİN FLAKON, 1 ADET …
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker ... It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride ... BREVIBLOC FLAKON 10 MG/ML IV KULLANIM İÇİN FLAKON, 1 ADET …
Rilonacept
Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Synonyms: … interleukin-1 (IL-1) trap ... IL-1 TRAP ... IL-1-TRAP …
Matched Description: … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein ... linked to the Fc portion of immunoglobulin G1. …
Matched Categories: … Interleukin-1 Blockers ... Receptors, Interleukin-1 Type I ... Interleukin-1 Receptor Accessory Protein …
Matched Description: … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein ... linked to the Fc portion of immunoglobulin G1. …
Matched Categories: … Interleukin-1 Blockers ... Receptors, Interleukin-1 Type I ... Interleukin-1 Receptor Accessory Protein …
Caffeine
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Synonyms: … 1-methyltheobromine …
Matched Description: … by the FDA in 1999. ... Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory ... This correlates to about 1 in 10 births. …
Matched Mixtures name: … DOLEX® FORTE NF ... DOLEX® FORTE NF ... Pancold A …
Matched Categories: … combinations of xanthines …
Matched Products: … KAFESIT 20 MG/ML IV ENJEKSIYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Matched Description: … by the FDA in 1999. ... Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory ... This correlates to about 1 in 10 births. …
Matched Mixtures name: … DOLEX® FORTE NF ... DOLEX® FORTE NF ... Pancold A …
Matched Categories: … combinations of xanthines …
Matched Products: … KAFESIT 20 MG/ML IV ENJEKSIYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Tezacaftor
Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class. It was developed by Vertex Pharmaceuticals and FDA approved in combination with ivacaftor to manage cystic fibrosis. This drug was approved by the FDA on February 12, 2018. Cystic Fibrosis is an autosomal recessive disorder caused...
Approved
Investigational
Matched Iupac: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)-N-{1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan ... -2-yl)-1H-indol-5-yl}cyclopropane-1-carboxamide …
Matched Description: … Alterations in the CFTR gene result in altered production, misfolding, or function of the protein and ... in the gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, an ion channel ... Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Alterations in the CFTR gene result in altered production, misfolding, or function of the protein and ... in the gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, an ion channel ... Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Simethicone
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Approved
Matched Description: … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas ... [A228308]
Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952 ... [A228308] It has a favourable safety profile as it is not systemically absorbed. …
Matched Mixtures name: … ซีมาเจล 1 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Lefax 42 mg Kautabletten …
Matched Mixtures name: … ซีมาเจล 1 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Lefax 42 mg Kautabletten …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Description: … Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration …
Matched Mixtures name: … PERINDO/IN RAT T 5/1.25 ... PERINDO/IN RAT T 5/1.25 ... PERINDO IN 1A PHA4/1.25MG …
Matched Categories: … Agents Acting on the Renin-Angiotensin System …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Description: … Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration …
Matched Mixtures name: … PERINDO/IN RAT T 5/1.25 ... PERINDO/IN RAT T 5/1.25 ... PERINDO IN 1A PHA4/1.25MG …
Matched Categories: … Agents Acting on the Renin-Angiotensin System …
Finasteride
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Synonyms: … (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide …
Matched Description: … aim to target the underlying disease by blocking the effects of the primary androgen involved in benign ... Finasteride is an orally active drug that was first approved by the FDA in 1992 for the treatment of ... It works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting …
Matched Categories: … Drugs Used in Benign Prostatic Hypertrophy …
Matched Products: … Sandoz Finasteride A ... Finasterid A-med 5 mg Filmtabletten ... แฮริฟิน - 1 …
Matched Description: … aim to target the underlying disease by blocking the effects of the primary androgen involved in benign ... Finasteride is an orally active drug that was first approved by the FDA in 1992 for the treatment of ... It works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting …
Matched Categories: … Drugs Used in Benign Prostatic Hypertrophy …
Matched Products: … Sandoz Finasteride A ... Finasterid A-med 5 mg Filmtabletten ... แฮริฟิน - 1 …
Displaying drugs 201 - 225 of 14555 in total